Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Vanessa Leone"'
Autor:
Jason Y. Zhang, Bingqing Xie, Hugo Barba, Urooba Nadeem, Asadolah Movahedan, Nini Deng, Melanie Spedale, Mark D’Souza, Wendy Luo, Vanessa Leone, Eugene B. Chang, Betty Theriault, Dinanath Sulakhe, Dimitra Skondra
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9676 (2022)
Studies have begun to reveal significant connections between the gut microbiome and various retinal diseases, including age-related macular degeneration (AMD). As critical supporting tissues of the retina, the retinal pigment epithelium (RPE) and und
Externí odkaz:
https://doaj.org/article/3f38d3bad162490ea8f13cbb2a6a8f24
Autor:
David Dao, Bingqing Xie, Urooba Nadeem, Jason Xiao, Asad Movahedan, Mark D’Souza, Vanessa Leone, Seenu M. Hariprasad, Eugene B. Chang, Dinanath Sulakhe, Dimitra Skondra
Publikováno v:
Cells, Vol 10, Iss 8, p 2119 (2021)
The relationship between retinal disease, diet, and the gut microbiome has shown increasing importance over recent years. In particular, high-fat diets (HFDs) are associated with development and progression of several retinal diseases, including age-
Externí odkaz:
https://doaj.org/article/65e436620ed548da9deb4328db649453
Autor:
Jun Miyoshi, Alexandria M. Bobe, Sawako Miyoshi, Yong Huang, Nathaniel Hubert, Tom O. Delmont, A. Murat Eren, Vanessa Leone, Eugene B. Chang
Publikováno v:
Cell Reports, Vol 20, Iss 2, Pp 491-504 (2017)
Factors affecting the developing neonatal gut microbiome and immune networks may increase the risk of developing complex immune disorders such as inflammatory bowel diseases (IBD). In particular, peripartum antibiotics have been suggested as risk fac
Externí odkaz:
https://doaj.org/article/f695e3d6247343a181c2510cb18a6bd7
Autor:
Xiang Zhong, Jiayao Yu, Katya Frazier, Xiaocheng Weng, Yi Li, Candace M. Cham, Kyle Dolan, Xiaorong Zhu, Nathaniel Hubert, Yun Tao, Fanfei Lin, Kristina Martinez-Guryn, Yong Huang, Tian Wang, Jianzhao Liu, Chuan He, Eugene B. Chang, Vanessa Leone
Publikováno v:
Cell Reports, Vol 25, Iss 7, Pp 1816-1828.e4 (2018)
Summary: Transcriptional regulation of circadian rhythms is essential for lipid metabolic homeostasis, disruptions of which can lead to metabolic diseases. Whether N6-methyladenosine (m6A) mRNA methylation impacts circadian regulation of lipid metabo
Externí odkaz:
https://doaj.org/article/5744aa4a5b6148c38cfecc26aa273e7c
Autor:
Jun Miyoshi, Vanessa Leone, Kentaro Nobutani, Mark W. Musch, Kristina Martinez-Guryn, Yunwei Wang, Sawako Miyoshi, Alexandria M. Bobe, A. Murat Eren, Eugene B. Chang
Publikováno v:
PeerJ, Vol 6, p e5166 (2018)
Murine models are widely used to explore host-microbe interactions because of the challenges and limitations inherent to human studies. However, microbiome studies in murine models are not without their nuances. Inter-individual variations in gut mic
Externí odkaz:
https://doaj.org/article/7e9eb28bfa1a4216bf60557308a105df
Autor:
Christian C Evans, Kathy J LePard, Jeff W Kwak, Mary C Stancukas, Samantha Laskowski, Joseph Dougherty, Laura Moulton, Adam Glawe, Yunwei Wang, Vanessa Leone, Dionysios A Antonopoulos, Dan Smith, Eugene B Chang, Mae J Ciancio
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92193 (2014)
Diet-induced obesity (DIO) is a significant health concern which has been linked to structural and functional changes in the gut microbiota. Exercise (Ex) is effective in preventing obesity, but whether Ex alters the gut microbiota during development
Externí odkaz:
https://doaj.org/article/f035416cc0fa4d47b8e7a6a371378eb1
Autor:
Sarah Schulz, Marina Iglesias-Cans, Alexander Krah, Ozkan Yildiz, Vanessa Leone, Doreen Matthies, Gregory M Cook, José D Faraldo-Gómez, Thomas Meier
Publikováno v:
PLoS Biology, Vol 11, Iss 6, p e1001596 (2013)
The anaerobic bacterium Fusobacterium nucleatum uses glutamate decarboxylation to generate a transmembrane gradient of Na⁺. Here, we demonstrate that this ion-motive force is directly coupled to ATP synthesis, via an F₁F₀-ATP synthase with a no
Externí odkaz:
https://doaj.org/article/314e0a549c3d4d76bf081a570d2bb2f2
Publikováno v:
PLoS Computational Biology, Vol 5, Iss 3, p e1000309 (2009)
Trans/cis prolyl isomerisation is involved in several biological processes, including the development of numerous diseases. In the HIV-1 capsid protein (CA), such a process takes place in the uncoating and recruitment of the virion and is catalyzed b
Externí odkaz:
https://doaj.org/article/43140c9b582c48639039a75d52ebd180
Autor:
Anne-Marie C Overstreet, Brady Anderson, McKenzie Burge, Xiaorong Zhu, Yun Tao, Candace Cham, Brenna Michaud, Soyar Horam, Naseer Sangwan, Mohammed Dwidar, Xuefeng Liu, Akeem Santos, Chelsea Finney, Zhanghan Dai, Vanessa Leone, Jeannette S Messer
Publikováno v:
bioRxiv
Mucosal barriers provide the first line of defense between internal body surfaces and microbial threats from the outside world. (1) In the colon, the barrier consists of two layers of mucus and a single layer of tightly interconnected epithelial cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c92eb6340e278c99491424c1539e8b
https://europepmc.org/articles/PMC10312563/
https://europepmc.org/articles/PMC10312563/
Autor:
Vanessa Leone, Richard T. Bradshaw, Caroline Koshy, Paul Suhwan Lee, Cristina Fenollar-Ferrer, Veronika Heinz, Christine Ziegler, Lucy R. Forrest
Membrane transporters mediate the passage of molecules across membranes and are essential for cellular function. While the transmembrane region of these proteins is responsible for substrate transport, often the cytoplasmic regions are required for m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d09239865b721eb31e1e6f93f1ff45fd
https://doi.org/10.1101/2022.06.05.494857
https://doi.org/10.1101/2022.06.05.494857