Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Vanessa Lakis"'
Autor:
Aimee L. Davidson, Uwe Dressel, Sarah Norris, Daffodil M. Canson, Dylan M. Glubb, Cristina Fortuno, Georgina E. Hollway, Michael T. Parsons, Miranda E. Vidgen, Oliver Holmes, Lambros T. Koufariotis, Vanessa Lakis, Conrad Leonard, Scott Wood, Qinying Xu, Amy E. McCart Reed, Hilda A. Pickett, Mohammad K. Al-Shinnag, Rachel L. Austin, Jo Burke, Elisa J. Cops, Cassandra B. Nichols, Annabel Goodwin, Marion T. Harris, Megan J. Higgins, Emilia L. Ip, Catherine Kiraly-Borri, Chiyan Lau, Julia L. Mansour, Michael W. Millward, Melissa J. Monnik, Nicholas S. Pachter, Abiramy Ragunathan, Rachel D. Susman, Sharron L. Townshend, Alison H. Trainer, Simon L. Troth, Katherine M. Tucker, Mathew J. Wallis, Maie Walsh, Rachel A. Williams, Ingrid M. Winship, Felicity Newell, Emma Tudini, John V. Pearson, Nicola K. Poplawski, Helen G. Mar Fan, Paul A. James, Amanda B. Spurdle, Nicola Waddell, Robyn L. Ward
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-16 (2023)
Abstract Background Many families and individuals do not meet criteria for a known hereditary cancer syndrome but display unusual clusters of cancers. These families may carry pathogenic variants in cancer predisposition genes and be at higher risk f
Externí odkaz:
https://doaj.org/article/e7517b7792c7450392b54b67bde9ca87
Autor:
Marjan M. Naeini, Felicity Newell, Lauren G. Aoude, Vanessa F. Bonazzi, Kalpana Patel, Guy Lampe, Lambros T. Koufariotis, Vanessa Lakis, Venkateswar Addala, Olga Kondrashova, Rebecca L. Johnston, Sowmya Sharma, Sandra Brosda, Oliver Holmes, Conrad Leonard, Scott Wood, Qinying Xu, Janine Thomas, Euan Walpole, G. Tao Mai, Stephen P. Ackland, Jarad Martin, Matthew Burge, Robert Finch, Christos S. Karapetis, Jenny Shannon, Louise Nott, Robert Bohmer, Kate Wilson, Elizabeth Barnes, John R. Zalcberg, B. Mark Smithers, John Simes, Timothy Price, Val Gebski, Katia Nones, David I. Watson, John V. Pearson, Andrew P. Barbour, Nicola Waddell
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Oesophageal adenocarcinoma is a poor prognosis cancer and the molecular features underpinning response to treatment remain unclear. We investigate whole genome, transcriptomic and methylation data from 115 oesophageal adenocarcinoma patients
Externí odkaz:
https://doaj.org/article/10a795104a0f4275aaca1728299e2389
Autor:
David Fielding, Vanessa Lakis, Andrew J. Dalley, Haarika Chittoory, Felicity Newell, Lambros T. Koufariotis, Ann-Marie Patch, Stephen Kazakoff, Farzad Bashirzadeh, Jung Hwa Son, Kimberley Ryan, Daniel Steinfort, Jonathan P. Williamson, Michael Bint, Carl Pahoff, Phan Tien Nguyen, Scott Twaddell, David Arnold, Christopher Grainge, Andrew Pattison, David Fairbairn, Shailendra Gune, Jemma Christie, Oliver Holmes, Conrad Leonard, Scott Wood, John V. Pearson, Sunil R. Lakhani, Nicola Waddell, Peter T. Simpson, Katia Nones
Publikováno v:
Cancers, Vol 16, Iss 4, p 785 (2024)
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is often the only source of tumor tissue from patients with advanced, inoperable lung cancer. EBUS-TBNA aspirates are used for the diagnosis, staging, and genomic testing to
Externí odkaz:
https://doaj.org/article/02291aae325b4ccbaf4b055c87c30b96
Autor:
David Fielding, Andrew J. Dalley, Mahendra Singh, Lakshmy Nandakumar, Vanessa Lakis, Haarika Chittoory, David Fairbairn, Ann-Marie Patch, Stephen H. Kazakoff, Kaltin Ferguson, Farzad Bashirzadeh, Michael Bint, Carl Pahoff, Jung Hwa Son, Kimberley Ryan, Alan Hodgson, Sowmya Sharma, John V. Pearson, Nicola Waddell, Sunil R. Lakhani, Gunter Hartel, Peter T. Simpson, Katia Nones
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionTumour Mutation Burden (TMB) is a potential biomarker for immune cancer therapies. Here we investigated parameters that might affect TMB using duplicate cytology smears obtained from endobronchial ultrasound transbronchial needle aspirati
Externí odkaz:
https://doaj.org/article/f59f51c4cc2242a2aa208dda6ce9e2fd
Autor:
Jenette Creaney, Ann-Marie Patch, Venkateswar Addala, Sophie A. Sneddon, Katia Nones, Ian M. Dick, Y. C. Gary Lee, Felicity Newell, Ebony J. Rouse, Marjan M. Naeini, Olga Kondrashova, Vanessa Lakis, Apostolos Nakas, David Waller, Annabel Sharkey, Pamela Mukhopadhyay, Stephen H. Kazakoff, Lambros T. Koufariotis, Aimee L. Davidson, Priya Ramarao-Milne, Oliver Holmes, Qinying Xu, Conrad Leonard, Scott Wood, Sean M. Grimmond, Raphael Bueno, Dean A. Fennell, John V. Pearson, Bruce W. Robinson, Nicola Waddell
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-18 (2022)
Abstract Background Malignant pleural mesothelioma (MPM) has a poor overall survival with few treatment options. Whole genome sequencing (WGS) combined with the immune features of MPM offers the prospect of identifying changes that could inform futur
Externí odkaz:
https://doaj.org/article/5bdff0d20d9746a283a822d97c8462e5
Autor:
Vanessa F. Bonazzi, Olga Kondrashova, Deborah Smith, Katia Nones, Asmerom T. Sengal, Robert Ju, Leisl M. Packer, Lambros T. Koufariotis, Stephen H. Kazakoff, Aimee L. Davidson, Priya Ramarao-Milne, Vanessa Lakis, Felicity Newell, Rebecca Rogers, Claire Davies, James Nicklin, Andrea Garrett, Naven Chetty, Lewis Perrin, John V. Pearson, Ann-Marie Patch, Nicola Waddell, Pamela M. Pollock
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-19 (2022)
Abstract Background Endometrial cancer (EC) is a major gynecological cancer with increasing incidence. It comprises four molecular subtypes with differing etiology, prognoses, and responses to chemotherapy. In the future, clinical trials testing new
Externí odkaz:
https://doaj.org/article/4b680dfc6fbc449d935cd19fb75a3b51
Autor:
Jamie R. Kutasovic, Katia Nones, Vanessa Lakis, Lambros T. Koufariotis, Kaltin Ferguson, Amy E. McCart Reed, Peter T. Simpson, Sunil R. Lakhani, Helen Mar Fan, Megan Higgins, Janene Davies, Diane Payton, Lucinda Taege
Publikováno v:
Human Pathology Reports, Vol 30, Iss , Pp 300678- (2022)
Lipoblastoma-like tumour of the vulva (LLTV) is a rare soft tissue neoplasm with only nineteen reported cases to date. The clinical behaviour in all cases has been benign, with a small number of local recurrences and no incidences of metastasis descr
Externí odkaz:
https://doaj.org/article/efd40250613b4258a27005c1a6033fee
Autor:
David Fielding, FRACP, MD, Andrew J. Dalley, PhD, Mahendra Singh, FRCPA, Lakshmy Nandakumar, FRCPA, Katia Nones, PhD, Vanessa Lakis, MBioinf, Haarika Chittoory, MBiotech, Kaltin Ferguson, Farzad Bashirzadeh, FRACP, Michael Bint, FRACP, Carl Pahoff, FRACP, Jung Hwa Son, RN, Alan Hodgson, CT ASC, Sowmya Sharma, FRCPA, David Godbolt, FRCPA, Kylie Coleman, CT ASC, Lenore Whitfield, CT ASC, Nicola Waddell, PhD, Sunil R. Lakhani, FRCPA, Gunter Hartel, PhD, Peter T. Simpson, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 3, Iss 10, Pp 100403- (2022)
Introduction: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS TBNA) is an important means of obtaining a tissue for advanced lung cancer. Optimizing the EBUS TBNA needling technique is important to maintain procedural simplicit
Externí odkaz:
https://doaj.org/article/a6f1ee6dc77241f38149b13163b10713
Autor:
Vanessa Lakis, Rita T. Lawlor, Felicity Newell, Ann-Marie Patch, Andrea Mafficini, Anguraj Sadanandam, Lambros T. Koufariotis, Rebecca L. Johnston, Conrad Leonard, Scott Wood, Borislav Rusev, Vincenzo Corbo, Claudio Luchini, Sara Cingarlini, Luca Landoni, Roberto Salvia, Michele Milella, David Chang, Peter Bailey, Nigel B. Jamieson, Fraser Duthie, Marie-Claude Gingras, Donna M. Muzny, David A. Wheeler, Richard A. Gibbs, Massimo Milione, APGI, ARC-Net, Paolo Pederzoli, Jaswinder S. Samra, Anthony J. Gill, Amber L. Johns, John V. Pearson, Andrew V. Biankin, Sean M. Grimmond, Nicola Waddell, Katia Nones, Aldo Scarpa
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Lakis et al. report novel findings related to the epigenetic landscape of pancreatic neuroendocrine cancer. This relatively large cohort provides functional insights into the epigenetic wiring of pancreatic neuroendocrine tumor sub-types with the pot
Externí odkaz:
https://doaj.org/article/a00f8e4047594060951453f3f2ee9216
Autor:
Felicity Newell, James S. Wilmott, Peter A. Johansson, Katia Nones, Venkateswar Addala, Pamela Mukhopadhyay, Natasa Broit, Carol M. Amato, Robert Van Gulick, Stephen H. Kazakoff, Ann-Marie Patch, Lambros T. Koufariotis, Vanessa Lakis, Conrad Leonard, Scott Wood, Oliver Holmes, Qinying Xu, Karl Lewis, Theresa Medina, Rene Gonzalez, Robyn P. M. Saw, Andrew J. Spillane, Jonathan R. Stretch, Robert V. Rawson, Peter M. Ferguson, Tristan J. Dodds, John F. Thompson, Georgina V. Long, Mitchell P. Levesque, William A. Robinson, John V. Pearson, Graham J. Mann, Richard A. Scolyer, Nicola Waddell, Nicholas K. Hayward
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Acral melanoma occurs on the soles of the feet, palms of the hands and in nail beds. Here, the authors reports the genomic landscape of 87 acral melanomas and find that some tumors harbor a UV signature and that the tumors are diverse at the levels o
Externí odkaz:
https://doaj.org/article/953bcceaafac4fed9eb837e6a8612ce4