Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Vanessa Klapp"'
Targeting mRNA translation aberrations: A novel approach for therapy in chronic lymphocytic leukemia
Publikováno v:
Cancer Communications, Vol 43, Iss 12, Pp 1373-1376 (2023)
Externí odkaz:
https://doaj.org/article/cfbdd2fc7dad421da286dc5422792a12
Autor:
Vanessa Klapp, Aitziber Buqué, Norma Bloy, Ai Sato, Takahiro Yamazaki, Xi Kathy Zhou, Silvia C. Formenti, Lorenzo Galluzzi, Giulia Petroni
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-10 (2023)
Abstract Background Preclinical evidence from us and others demonstrates that the anticancer effects of cyclin-dependent kinase 4/6 (CDK4/6) inhibitors can be enhanced with focal radiation therapy (RT), but only when RT is delivered prior to (rather
Externí odkaz:
https://doaj.org/article/2b53eb703bf9446c8d4b1b0cd0e30b9f
Autor:
Anne Largeot, Vanessa Klapp, Elodie Viry, Susanne Gonder, Iria Fernandez Botana, Arnaud Blomme, Mohaned Benzarti, Sandrine Pierson, Chloé Duculty, Petra Marttila, Marina Wierz, Ernesto Gargiulo, Giulia Pagano, Ning An, Najla El Hachem, Daniel Perez Hernandez, Supriya Chakraborty, Loic Ysebaert, Jean-Hugues François, Susan Cortez, Guy Berchem, Dimitar G Efremov, Gunnar Dittmar, Martyna Szpakowska, Andy Chevigne, Petr V. Nazarov, Thomas Helleday, Pierre Close, Johannes Meiser, Basile Stamatopoulos, Laurent Désaubry, Jérôme Paggetti, Etienne Moussay
Publikováno v:
HemaSphere, Vol 7, p e52627ab (2023)
Externí odkaz:
https://doaj.org/article/cadb7e0ab439425bb2d02339f658e7b0
Autor:
Vanessa Klapp, Beatriz Álvarez-Abril, Giuseppe Leuzzi, Guido Kroemer, Alberto Ciccia, Lorenzo Galluzzi
Publikováno v:
Cancer Discovery. :OF1-OF25
Genomic stability in normal cells is crucial to avoid oncogenesis. Accordingly, multiple components of the DNA damage response (DDR) operate as bona fide tumor suppressor proteins by preserving genomic stability, eliciting the demise of cells with un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3526781af48f68a15e9832dd9f56ec82
https://doi.org/10.1158/2159-8290.cd-22-1220
https://doi.org/10.1158/2159-8290.cd-22-1220
Publikováno v:
Essays in Biochemistry.
Focal radiation therapy (RT) has been successfully employed to clinically manage multiple types of cancer for more than a century. Besides being preferentially cytotoxic for malignant cells over their nontransformed counterparts, RT elicits numerous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3265bf9f6b635592e85ea12597aa917a
https://doi.org/10.1042/ebc20220248
https://doi.org/10.1042/ebc20220248
Autor:
Anne Largeot, Vanessa Klapp, Elodie Viry, Susanne Gonder, Iria Fernandez Botana, Arnaud Blomme, Mohaned Benzarti, Sandrine Pierson, Chloé Duculty, Petra Marttila, Marina Wierz, Ernesto Gargiulo, Giulia Pagano, Ning An, Najla El Hachem, Daniel Perez Hermandez, Supriya Chakraborty, Loïc Ysebaert, Jean-Hugues François, Susan Denisse Cortez Clemente, Guy Berchem, Dimitar G Efremov, Gunnar Dittmar, Martyna Szpakowska, Andy Chevigne, Petr V Nazarov, Thomas Helleday, Pierre Close, Johannes Meiser, Basile Stamatopoulos, Laurent Désaubry, Jerome Paggetti, Etienne Moussay
Publikováno v:
Blood Journal.
Dysregulation of mRNA translation, including preferential translation of mRNA with complex 5'-UTRs such as the MYC oncogene, is recognized as an important mechanism in cancer. In this study, we show that both human and murine chronic lymphocytic leuk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3f45f16ca8ae2c852c2d7f49b221a91
https://doi.org/10.1182/blood.2022017839
https://doi.org/10.1182/blood.2022017839
Autor:
Lorenzo Galluzzi, Alberto Ciccia, Guido Kroemer, Giuseppe Leuzzi, Beatriz Álvarez-Abril, Vanessa Klapp
NHEJ and inflammation in cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a525ee1c47143b9e327debdb31131d
https://doi.org/10.1158/2159-8290.22574596
https://doi.org/10.1158/2159-8290.22574596
Autor:
Lorenzo Galluzzi, Alberto Ciccia, Guido Kroemer, Giuseppe Leuzzi, Beatriz Álvarez-Abril, Vanessa Klapp
BER and inflammation in cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc378a25141a51ccb13e004382ba204d
https://doi.org/10.1158/2159-8290.22574602.v1
https://doi.org/10.1158/2159-8290.22574602.v1
Autor:
Lorenzo Galluzzi, Alberto Ciccia, Guido Kroemer, Giuseppe Leuzzi, Beatriz Álvarez-Abril, Vanessa Klapp
PARP signaling and inflammation in cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4254cd79f0ad1231a9af402f04131d01
https://doi.org/10.1158/2159-8290.22574590.v1
https://doi.org/10.1158/2159-8290.22574590.v1
Autor:
Lorenzo Galluzzi, Alberto Ciccia, Guido Kroemer, Giuseppe Leuzzi, Beatriz Álvarez-Abril, Vanessa Klapp
DDR signaling and inflammation in cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::548a6bd4e43e1c27a01779d627d8fc66
https://doi.org/10.1158/2159-8290.22574587
https://doi.org/10.1158/2159-8290.22574587