Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Vanessa Kermer"'
PDF file, 42KB, supplemental data, S2, HPLC analysis data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e48fb36c63412b70f03e0aee846f76e
https://doi.org/10.1158/1535-7163.22496644
https://doi.org/10.1158/1535-7163.22496644
Autor:
Dafne Müller, Roland E. Kontermann, Anastasiia Bondarieva, Markus Harder, Nora Hornig, Vanessa Kermer
PDF - 170KB, Combined effect of IL-15 and scFv_4-1BBL on the proliferation (A) and IFN-γ release (B) of activated T cells and PBMCs, respectively.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ec8dbac7d72b4673251b58ee596a40
https://doi.org/10.1158/1535-7163.22503421.v1
https://doi.org/10.1158/1535-7163.22503421.v1
Autor:
Dafne Müller, Roland E. Kontermann, Anastasiia Bondarieva, Markus Harder, Nora Hornig, Vanessa Kermer
PDF - 49KB, Comparison of the cytokine activity of RD_IL-15_scFv and scFv_RD_IL-15.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d1787361bd4265ba41047e969f14b46
https://doi.org/10.1158/1535-7163.22503415.v1
https://doi.org/10.1158/1535-7163.22503415.v1
Autor:
Dafne Müller, Roland E. Kontermann, Anastasiia Bondarieva, Markus Harder, Nora Hornig, Vanessa Kermer
PDF - 61KB, Functional activity of RD_IL-15_scFv_m4-1BBL.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46e98379bc1ea3fb3f9eff9c69ec9ee2
https://doi.org/10.1158/1535-7163.22503418.v1
https://doi.org/10.1158/1535-7163.22503418.v1
Cytokines driving the immune response are powerful tools for cancer immunotherapy, but their application is generally limited by severe systemic toxicity. Targeted approaches by means of antibody–cytokine fusion proteins might enable focus on the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::411b2565ddfbeed1b334ce93fe2d6326
https://doi.org/10.1158/1535-7163.c.6535351
https://doi.org/10.1158/1535-7163.c.6535351
PDF file, 64KB, supplemental data, S1, Cloning, expression and purification of the recombinant fusion proteins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b38e938e259d5a6c711991e43fc8a6e2
https://doi.org/10.1158/1535-7163.22496641
https://doi.org/10.1158/1535-7163.22496641
Autor:
Katharina Frey, Dafne Müller, Nora Hornig, Philipp Diebolder, Roland E. Kontermann, Vanessa Kermer
Publikováno v:
Journal of Immunotherapy. 35:418-429
Initiation of a tumor-directed immune response and appropriate modulation of its progress are key issues in cancer immunotherapy. Combinatorial strategies addressing both aspects might therefore be especially suitable. Here, we report a targeted appr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6e1434925ae56ae5c8f091f78312737
https://doi.org/10.1097/cji.0b013e3182594387
https://doi.org/10.1097/cji.0b013e3182594387
Autor:
Nora Hornig, Anastasiia Bondarieva, Vanessa Kermer, Roland E. Kontermann, Markus Harder, Dafne Müller
Publikováno v:
Molecular cancer therapeutics. 13(1)
Influencing the cytokine receptor network that modulates the immune response holds great potential for cancer immunotherapy. Although encouraging results have been obtained by focusing on individual members of the common γ-chain (γc) receptor famil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c15f69fc41ebeea9686c2a5754becc
https://pubmed.ncbi.nlm.nih.gov/24198185
https://pubmed.ncbi.nlm.nih.gov/24198185
Publikováno v:
Cancer immunology, immunotherapy : CII. 62(8)
Combinatory strategies are becoming of increasing interest in cancer immunotherapy. Costimulation by individual members of the immunoglobulin-like (Ig)- and TNF superfamily have already shown promising antitumor potential, thus prompting the explorat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3658ba486e985deea780c36f584079c9
https://pubmed.ncbi.nlm.nih.gov/23715927
https://pubmed.ncbi.nlm.nih.gov/23715927
Publikováno v:
Molecular cancer therapeutics. 11(6)
Cytokines driving the immune response are powerful tools for cancer immunotherapy, but their application is generally limited by severe systemic toxicity. Targeted approaches by means of antibody–cytokine fusion proteins might enable focus on the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3be2b295e95f4916cfcba73f799dff
https://pubmed.ncbi.nlm.nih.gov/22491823
https://pubmed.ncbi.nlm.nih.gov/22491823