Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Vanessa Kainz"'
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103929 (2014)
Dynamic thalamic regulation of sensory signals allows the cortex to adjust better to rapidly changing behavioral, physiological and environmental demands. To fulfill this role, thalamic neurons must themselves be subjected to constantly changing modu
Externí odkaz:
https://doaj.org/article/817e9bae51ba4f36a15b38d32b9ce483
Publikováno v:
Cytokine. 113:238-247
Human macrophages produce vascular endothelial growth factor A (VEGFA) for angiogenesis in diabetic retinopathy (DR). The regulatory function of IL-27 on human macrophages is not well understood. In particular, the effect of IL-27 on VEGFA response i
Autor:
Joanna Vrouvlianis, Xiaoqiu Wu, Christie L. Bell, Viral Kansara, Q Medley, Henry Y. Wu, Qian Huang, Hui Li, Terri L. McGee, Barrett Leehy, Vanessa Kainz, Melissa Prentiss, YongYao Xu, A.P. da Cunha, Qin Zhang, Chad E Bigelow, Nalini Rangaswamy
Publikováno v:
Current Eye Research. 43:553-565
The concept of tissue-dependent cytokine hierarchy has been demonstrated in a number of diseases, but it has not been investigated in ophthalmic diseases. Here, we evaluated the functional hierarchy of interleukin-1β (IL-1β), IL-6, IL-17A, and tumo
Autor:
Lino Becerra, Rami Burstein, Vanessa Kainz, Pei-Ching Chang, Gabi Barmettler, David Borsook, James Bishop
Publikováno v:
Pain
Migraine is a debilitating condition; however, the pharmacological effects on central nervous system networks after successful therapy are poorly understood. Defining this neurocircuitry is critical to our understanding of the disorder and for the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5820fbe2c8477cfb89cfacc5384f6b0
https://europepmc.org/articles/PMC7193782/
https://europepmc.org/articles/PMC7193782/
Advances in our understanding of the human pain experience have shifted much of the focus of pain research from the periphery to the brain. Current hypotheses suggest that the progression of migraine depends on abnormal functioning of neurons in mult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ff85c4d2bc62edd632a7746b0f3f98
https://europepmc.org/articles/PMC5731648/
https://europepmc.org/articles/PMC5731648/
Publikováno v:
Neuroscience. 248:359-368
Migraine attacks are typically described as unilateral, throbbing pain that is usually accompanied by nausea, vomiting, and exaggerated sensitivities to light, noise and smell. The headache phase of a migraine attack is mediated by activation of the
Autor:
Michael S. Gold, Rami Burstein, Vanessa Kainz, XiChun Zhang, Catherine Buettner, Moshe Jakubowski
Publikováno v:
Epilepsy & Behavior. 28:243-248
We proposed recently that induction of delayed activation of trigeminovascular neurons by cortical spreading depression (CSD) can explain the delayed onset of headache after the migraine aura ("aura"). This prompted us to search for ways to block the
Publikováno v:
Annals of Neurology. 73:741-750
Objective To examine changes in the response properties of meningeal nociceptors that might lead to migraine pain and examine endogenous processes that could play a role in mediating them using a clinically relevant model of migraine triggering, name
Publikováno v:
Pain. 152:140-149
The proinflammatory cytokine TNF-alpha has been shown to promote activation and sensitization of primary afferent nociceptors. The downstream signaling processes that play a role in promoting this neuronal response remain however controversial. Incre
Publikováno v:
Journal of Neuroscience. 30:8807-8814
Attacks of migraine with aura represent a phenomenon in which abnormal neuronal activity in the cortex produces sensory disturbances (aura) some 20-40 min before the onset of headache. The purpose of this study was to determine whether cortical sprea