Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Vanessa J. Briscoe"'
Publikováno v:
Expert opinion on investigational drugs. 28(4)
DPP-4 inhibitors have pleomorphic effects that extend beyond the anti-hyperglycemic labeled use of the drug. DPP-4 inhibitors have demonstrated promising renal protective effects in T2DM and T1DM and protective effects against immune destruction of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93c089b9cb09520cd2587e465c9623e2
https://pubmed.ncbi.nlm.nih.gov/30848158
https://pubmed.ncbi.nlm.nih.gov/30848158
Autor:
Stephen N. Davis, Vanessa J. Briscoe
Publikováno v:
Expert review of endocrinologymetabolism. 1(4)
Inhaled human insulin (Exubera®) has been approved by the FDA and other regulatory bodies for treatment in Type 1 and 2 diabetes in the USA. It is the first alternative to injectable insulin since the discovery of the insulin compound to treat diabe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e3932630e86fb6552161529f7efc4a7
https://pubmed.ncbi.nlm.nih.gov/30290460
https://pubmed.ncbi.nlm.nih.gov/30290460
Autor:
Sofio Dumbadze, Stephen N. Davis, Vanessa J. Briscoe, Maka S. Hedrington, Donna B. Tate, Maia Mikeladze, Evan Thayer
Publikováno v:
Diabetes. 67
In this study we have tested the hypothesis that levels of epinephrine simulating those occurring during hypoglycemia of 70, 60, or 50 mg/dl will result in pro-coagulant and pro-atherothrombotic responses and endothelial dysfunction. 32 healthy human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6515e17c94aaa30255741ca7bae9a53
https://doi.org/10.2337/db18-198-or
https://doi.org/10.2337/db18-198-or
Autor:
Lisa M. Younk, Maka S. Hedrington, Zhihui Wang, Donna B. Tate, M. Antoinette Richardson, Wendell Nicholson, Nino G. Joy, Stephen N. Davis, Vanessa J. Briscoe
Publikováno v:
Diabetes Care
OBJECTIVE To determine the pharmacokinetic and pharmacodynamic dose-response effects of insulin glargine administered subcutaneously in individuals with type 2 diabetes. RESEARCH DESIGN AND METHODS Twenty obese type 2 diabetic individuals (10 male an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db2163d8e2b52eaa6ef0c3fa72525c0a
https://doi.org/10.2337/dc09-2011
https://doi.org/10.2337/dc09-2011
Publikováno v:
Expert Opinion on Drug Metabolism & Toxicology. 6:225-235
Importance of the field: Type 2 diabetes mellitus (T2DM) is increasingly prevalent throughout the world; controlling glycemia is an important part of preventing serious complications of diabetes. Sulfonylureas have been used in the treatment of type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f874fc26624085d21d47831f719954
https://doi.org/10.1517/17425250903512955
https://doi.org/10.1517/17425250903512955
Autor:
Vanessa J. Briscoe, Nino G. Joy, Donna B. Tate, Maka S. Hedrington, Stephen N. Davis, Andrew C. Ertl
Publikováno v:
Diabetes Care
OBJECTIVE Recent large randomized trials have linked adverse cardiovascular and cerebrovascular events with hypoglycemia. However, the integrated physiological and vascular biological mechanisms occurring during hypoglycemia have not been extensively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0483f7eab34d1cfe13e7f13a080d0f21
http://europepmc.org/articles/PMC2890354
http://europepmc.org/articles/PMC2890354
Publikováno v:
Diabetes
OBJECTIVE Antecedent hypoglycemia can blunt neuroendocrine and autonomic nervous system responses to next-day exercise in type 1 diabetes. The aim of this study was to determine whether antecedent increase of plasma cortisol is a mechanism responsibl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84d9d54c6c9b8f60143fc4f5c9a5c825
http://europepmc.org/articles/PMC2731524
http://europepmc.org/articles/PMC2731524
Publikováno v:
Diabetes. 58:701-709
OBJECTIVE—The physiology of counterregulatory responses during hypoglycemia in intensively treated type 2 diabetic subjects is largely unknown. Therefore, the specific aims of the study tested the hypothesis that 1) 6 months of intensive therapy to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbcfe1683efc30edb894dc689b0644ae
https://doi.org/10.2337/db08-1230
https://doi.org/10.2337/db08-1230
Publikováno v:
Diabetes
OBJECTIVE—Previous work has demonstrated that chronic administration of the serotonin reuptake inhibitor (SSRI) fluoxetine augments counterregulatory responses to hypoglycemia in healthy humans. However, virtually no information exists regarding th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0efe085119e0cef69da6bc376158c7a8
http://europepmc.org/articles/PMC2584138
http://europepmc.org/articles/PMC2584138
Publikováno v:
Diabetes
OBJECTIVE—Hypoglycemia commonly occurs in intensively-treated diabetic patients. Repeated hypoglycemia blunts counterregulatory responses, thereby increasing the risk for further hypoglycemic events. Currently, physiologic approaches to augment cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26bdf280b4bc98881ad9cf606730116b
http://europepmc.org/articles/PMC2518497
http://europepmc.org/articles/PMC2518497