Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Vanessa J. Auld"'
Glial cells in the peripheral nerve wrap axons to insulate them and ensure efficient conduction of neuronal signals. In the myelin sheath, it is proposed that the autotypic tight junctions and adherens junctions form glia-glia complexes that stabiliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::290513f156e1a5cdcecaa97b3785649b
https://doi.org/10.1101/2022.11.01.514384
https://doi.org/10.1101/2022.11.01.514384
Glia are essential to protecting and enabling nervous system function and a key glial function is the formation of the glial sheath around peripheral axons. Each peripheral nerve in theDrosophilalarva is ensheathed by three glial layers, which struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16db80e152772d8fe57d8680f28952f7
https://doi.org/10.1101/2022.07.12.499769
https://doi.org/10.1101/2022.07.12.499769
Autor:
Vanessa J. Auld, Zohreh Sharifkhodaei
Publikováno v:
Genome. 64:97-108
Epithelial junctions ensure cell–cell adhesion and establish permeability barriers between cells. At the corners of epithelia, the tricellular junction (TCJ) is formed by three adjacent epithelial cells and generates a functional barrier. In Drosop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd3790403ff0f43a327d5d4c8888fb80
https://doi.org/10.1139/gen-2020-0026
https://doi.org/10.1139/gen-2020-0026
Autor:
Mojgan Padash Barmchi, Mary Gilbert, Miranda Thomas, Lawrence Banks, Bing Zhang, Vanessa J Auld
Publikováno v:
PLoS Pathogens, Vol 12, Iss 8, p e1005789 (2016)
Cervical cancer is one of the leading causes of cancer death in women worldwide. The causative agents of cervical cancers, high-risk human papillomaviruses (HPVs), cause cancer through the action of two oncoproteins, E6 and E7. The E6 oncoprotein coo
Externí odkaz:
https://doaj.org/article/e7f86b6f1ba147aba87c128b9312591a
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153259 (2016)
The mammalian MAGI proteins play important roles in the maintenance of adherens and tight junctions. The MAGI family of proteins contains modular domains such as WW and PDZ domains necessary for scaffolding of membrane receptors and intracellular sig
Externí odkaz:
https://doaj.org/article/b92966b92e8040069515aeee9570529a
Publikováno v:
The Journal of Neuroscience. 40:3360-3373
TheDrosophilanervous system is ensheathed by a layer of outer glial cells, the perineurial glia, and a specialized extracellular matrix, the neural lamella. The function of perineurial glial cells and how they interact with the extracellular matrix a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79dc4a5658edfbed1d363fabf2232422
https://doi.org/10.1523/jneurosci.1397-19.2020
https://doi.org/10.1523/jneurosci.1397-19.2020
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37876 (2012)
Glia are integral participants in synaptic physiology, remodeling and maturation from blowflies to humans, yet how glial structure is coordinated with synaptic growth is unknown. To investigate the dynamics of glial development at the Drosophila larv
Externí odkaz:
https://doaj.org/article/96c24a6f9a5d442dba7a6e781fa66f3f
C-terminal Src kinase (Csk) regulates the tricellular junction protein Gliotactin independent of Src
Autor:
Gayathri Samarasekera, Vanessa J. Auld
Publikováno v:
Molecular Biology of the Cell
The tricellular junction (TCJ) forms at the convergence of three neighboring epithelia. The targeting of Gliotactin, an essential TCJ protein, to the TCJ is controlled by phosphorylation and endocytosis. C-terminal Src kinase controls endocytosis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94d90844957527f9d9539344d25cfcea
https://doi.org/10.1091/mbc.e17-04-0251
https://doi.org/10.1091/mbc.e17-04-0251
Publikováno v:
Development.
Junctional complexes that mediate cell adhesion are key to epithelial integrity, cell division and permeability barriers formation. In Drosophila the scaffolding proteins Scribble (Scrib) and Discs-large (Dlg) are key regulators of epithelial polarit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d47dbb4f95b9f2cbfbff373b9dd93dcb
https://doi.org/10.1242/dev.174763
https://doi.org/10.1242/dev.174763
Publikováno v:
Development. 141:3072-3083
Many aspects of glial development are regulated by extracellular signals, including those from the extracellular matrix (ECM). Signals from the ECM are received by cell surface receptors, including the integrin family. Previously, we have shown that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::839805e4f9a78a0f3e05627b771812d3
https://doi.org/10.1242/dev.101972
https://doi.org/10.1242/dev.101972