Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Vanessa Hsei"'
Publikováno v:
Pharmaceutical Research. 19:1753-1756
Angiogenesis plays a critical role in several physiologic and pathologic processes, particularly in tumor growth, invasion, and metastasis (1). New blood vessels provide tumors with nutrients necessary for growth and also remove metabolic waste from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9137f904d2bb5d286c7115cfc4ac28b
https://doi.org/10.1023/a:1020778001267
https://doi.org/10.1023/a:1020778001267
Autor:
Rene Ekert, Jun Liu, Wai Lee Wong, Vanessa Hsei, Gilbert A. Keller, Kathy D. Miller, Steven Sherwood, Mark X. Sliwkowski, David A. Lawrence, Gloria Meng, Laura DeForge, Jacques Gaudreault, Avi Ashkenazi, Amy Hurst, Leonard G. Presta
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 170(9)
Some Abs are more efficacious after being cross-linked to form dimers or multimers, presumably as a result of binding to and clustering more surface target to either amplify or diversify cellular signaling. To improve the therapeutic potency of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8af05856762cfb851aa079e0608ad4
https://pubmed.ncbi.nlm.nih.gov/12728922
https://pubmed.ncbi.nlm.nih.gov/12728922
Publikováno v:
Pharmaceutical research. 19(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d5cbac34f27c8d96307a725d5c4f0122
https://pubmed.ncbi.nlm.nih.gov/12458683
https://pubmed.ncbi.nlm.nih.gov/12458683
Autor:
Walter Galan, Steven R. Leong, Iphigenia Koumenis, Caroline Hebert, Gerardo A. Zapata, Vanessa Hsei, Daniel Tumas, James Deveney, Peter Gribling, Anan Chuntharapai, Patrick McKay, Wyne P. Lee, Daljit S. Narindray, K. Jin Kim, Laura DeForge, Marcel Reichert, Audrey Fan, Brian Wagner, Brad Snedecor, Monika B. Schoenhoff, Victoria Hale, Zahra Shahrokh, Tania Gonzalez, Leonard G. Presta, Han Chen
Publikováno v:
Cytokine. 16(3)
A neutralizing anti-interleukin-(IL-)8 monoclonal antibody was humanized by grafting the complementary determining regions onto the human IgG framework. Subsequent alanine scanning mutagenesis and phage display enabled the production of an affinity m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de36f52f17b26b6fca42c29dd3847113
https://pubmed.ncbi.nlm.nih.gov/11741351
https://pubmed.ncbi.nlm.nih.gov/11741351