Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Vanessa Hogan"'
Autor:
Michael Clarke, Vanessa Hogan, Deborah Buck, Jing Shen, Christine Powell, Chris Speed, Peter Tiffin, John Sloper, Robert Taylor, Mahmoud Nassar, Kerry Joyce, Fiona Beyer, Richard Thomson, Luke Vale, Elaine McColl, Nick Steen
Publikováno v:
Health Technology Assessment, Vol 19, Iss 39 (2015)
Introduction: The evidence base for the treatment of strabismus (squint) is poor. Our main aim is to improve this evidence base for the treatment of a common type of childhood squint {intermittent exotropia, [X(T)]}. We conducted an external pilot st
Externí odkaz:
https://doaj.org/article/aa534be6b147492084471bb47242701f
Autor:
Steve Iliffe, Amy Waugh, Marie Poole, Claire Bamford, Katie Brittain, Carolyn Chew-Graham, Chris Fox, Cornelius Katona, Gill Livingston, Jill Manthorpe, Nick Steen, Barbara Stephens, Vanessa Hogan, Louise Robinson, for the CAREDEM research team
Publikováno v:
Health Technology Assessment, Vol 18, Iss 52 (2014)
Background: People with dementia and their families need support in different forms, but currently services are often fragmented with variable quality of care. Case management offers a way of co-ordinating services along the care pathway and therefor
Externí odkaz:
https://doaj.org/article/408fd7d238b746d2b2ee5af0899a5524
Publikováno v:
European Journal of Paediatric Neurology. 20:560-565
Objective To establish the efficacy and tolerability of inhaled 5% carbon dioxide/95% oxygen as a treatment for paediatric non-convulsive status epilepticus (NCSE). Methods In an open label clinical trial, children in NCSE were given high flow inhale
Autor:
Peter Tiffin, Michael P. Clarke, Vanessa Hogan, Robert Taylor, Christine Powell, Chris Speed, Deborah Buck, John J. Sloper
Publikováno v:
Clinical Trials. 12:384-393
Background Intermittent exotropia is the most common form of divergent strabismus (squint) in children. Evidence regarding its optimum management is limited. A pilot randomised controlled trial has recently been completed (Surgery versus Active Monit
Autor:
David F. Choy, Jason A. Hackney, Jacob M van Laar, Y K Onno Teng, Sarah K. Kummerfeld, Vanessa Hogan, Michael J. Townsend, Cecile T.J. Holweg
Publikováno v:
Annals of the Rheumatic Diseases. 71:1888-1894
ObjectivePersonalised healthcare is contingent on the identification of biomarkers that represent disease relevant pathways and predict drug response. The authors aimed to develop a gene expression signature in synovial tissue that could enrich clini
Publikováno v:
Arthritis & Rheumatism. 63:795-799
Objective To describe the cellular source of transforming growth factor β (TGFβ) in the dermis of patients with systemic sclerosis (SSc). Methods We performed electron microscopy (EM) with immunogold labeling on skin biopsy specimens from 7 patient
Autor:
Helen A. L. Tuppen, Zofia M.A. Chrzanowska-Lightowlers, Robert W. Taylor, David R. Thorburn, Michael Clarke, Vanessa Hogan, Lisa Worgan, Anita M. Devlin, Charlotte L. Alston, Emma L. Blakely, Gabriele Saretzki, Simon Jones, Langping He, Robert McFarland, Mazhor Al-Dosary, A. A. M. Morris, Sahar Mansour
Publikováno v:
Brain
Isolated complex I deficiency is the most frequently observed oxidative phosphorylation defect in children with mitochondrial disease, leading to a diverse range of clinical presentations, including Leigh syndrome. For most patients the genetic cause
Publikováno v:
The Open Arthritis Journal. 3:32-36
There is increasing evidence that B cells can play important roles in the pathogenesis of various autoimmune diseases, either by autoantibody secretion, production of proinflammatory cytokines or autoantigen presentation. An in- creasing number of B
Autor:
Mark McLaughlin, Douglass M. Turnbull, Ian R. Griffiths, Saadia A. Karim, Julia M. Edgar, Vanessa Hogan, Kathryn White, Philip P. Nichols, Alison McGill
Publikováno v:
Journal of Neuroscience Research. 87:452-459
We used the Plp1-overexpressing transgenic mouse model to investigate whether progressive demyelination of axons results in adaptive changes involving mitochondria within the axons. These models have myelinated axons from birth but gradually lose mye
Autor:
Vanessa J. Davies, Stuart James Moat, Philip P. Nichols, Vanessa Hogan, Michael A. Wride, David G. Brownstein, Michael E. Boulton, Wan Fen Yip, Andrew John Hollins, Marcela Votruba, Malgorzata Piechota, Kathryn E. White, Kathryn Ann Powell, Jennifer Rhian Davies
Publikováno v:
Brain. 131:368-380
Opa3 mRNA is expressed in all tissues examined to date, but currently the function of the OPA3 protein is unknown. Intriguingly, various mutations in the OPA3 gene lead to two similar diseases in humans: autosomal dominant inherited optic atrophy and