Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Vanessa Gómez-Vallejo"'
Autor:
Claudia Esposito, María Gómez, Balbino Yagüe, Sandra Yeste, Raquel F. Reinoso, Vanessa Gómez-Vallejo, Gemma Arsequell, Jordi Llop
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S400- (2023)
Externí odkaz:
https://doaj.org/article/dda1f41f60c14788bd22630631f90857
Autor:
Sameer M. Joshi, Thomas C. Wilson, Zibo Li, Sean Preshlock, Vanessa Gómez-Vallejo, Véronique Gouverneur, Jordi Llop, Gemma Arsequell
Publikováno v:
Molecules, Vol 29, Iss 2, p 488 (2024)
The small-molecule iododiflunisal (IDIF) is a transthyretin (TTR) tetramer stabilizer and acts as a chaperone of the TTR-Amyloid beta interaction. Oral administration of IDIF improves Alzheimer’s Disease (AD)-like pathology in mice, although the me
Externí odkaz:
https://doaj.org/article/49e31f0bd8c144acb9b7ec8bd1defc30
Autor:
Luka Rejc, Vanessa Gómez-Vallejo, Ana Joya, Gemma Arsequell, Ander Egimendia, Pilar Castellnou, Xabier Ríos-Anglada, Unai Cossío, Zuriñe Baz, Leyre Iglesias, Estibaliz Capetillo-Zarate, Pedro Ramos-Cabrer, Abraham Martin, Jordi Llop
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-14 (2022)
Abstract Background Validation of new biomarkers of Alzheimer disease (AD) is crucial for the successful development and implementation of treatment strategies. Additional to traditional AT(N) biomarkers, neuroinflammation biomarkers, such as translo
Externí odkaz:
https://doaj.org/article/891cd9332c3e445593fa1436c0d14dde
Autor:
Rebeca Diez-Alarcia, Carolina Muguruza, Guadalupe Rivero, Aintzane García-Bea, Vanessa Gómez-Vallejo, Luis F. Callado, Jordi Llop, Abraham Martín, J. Javier Meana
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The status of serotonin 5HT2A receptors (5HT2ARs) in schizophrenia has been controversial. In vivo positron emission tomography neuroimaging and in vitro post-mortem binding studies have reported conflicting results about 5HT2AR densit
Externí odkaz:
https://doaj.org/article/ab7a5744879b4c13a57c83edf01eeb7b
Autor:
Rossana Passannante, Vanessa Gómez-Vallejo, Maialen Sagartzazu-Aizpurua, Laura Vignau Arsuaga, Pablo Marco-Moreno, Garazi Aldanondo, Ainara Vallejo-Illarramendi, Pablo Aguiar, Unai Cossío, Abraham Martín, Jonas Bergare, Lee Kingston, Charles S. Elmore, Miguel Angel Morcillo, Pablo Ferrón, Jesus M. Aizpurua, Jordi Llop
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 253 (2023)
Background and objective: The determination of pharmacokinetic properties of new chemical entities is a key step in the process of drug development. Positron emission tomography (PET) is an ideal technique to obtain both biodistribution and pharmacok
Externí odkaz:
https://doaj.org/article/ed7d132499034dc9b7f57f0c9ecdfc0f
Autor:
María Ardaya, Ana Joya, Daniel Padro, Sandra Plaza-García, Vanessa Gómez-Vallejo, Mercedes Sánchez, Maider Garbizu, Unai Cossío, Carlos Matute, Fabio Cavaliere, Jordi Llop, Abraham Martín
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
In vivo positron emission tomography of neuroinflammation has mainly focused on the evaluation of glial cell activation using radiolabeled ligands. However, the non-invasive imaging of neuroinflammatory cell proliferation has been scarcely evaluated
Externí odkaz:
https://doaj.org/article/33ac99b852334670a98664c95a457e99
Autor:
Krishna R. Pulagam, Lorena Colás, Daniel Padro, Sandra Plaza-García, Vanessa Gómez-Vallejo, Makoto Higuchi, Jordi Llop, Abraham Martín
Publikováno v:
EJNMMI Research, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Background In vivo positron-emission tomography (PET) imaging of transporter protein (TSPO) expression is an attractive and indispensable tool for the diagnosis and therapy evaluation of neuroinflammation after cerebral ischemia. Despite sev
Externí odkaz:
https://doaj.org/article/0b3ceeaa5a3d4aa2b4b760708a44832a
Publikováno v:
Molecules, Vol 20, Iss 5, Pp 7495-7508 (2015)
Dicarba-closo-dodecaboranes, commonly known as carboranes, possess unique physico-chemical properties and can be used as hydrophobic moieties during the design of new drugs or radiotracers. In this work, we report the synthesis of two analogues of 2-
Externí odkaz:
https://doaj.org/article/a219019e3bf744d383147a93b586f239
Autor:
Krishna R. Pulagam, Kiran B. Gona, Vanessa Gómez-Vallejo, Jan Meijer, Carolin Zilberfain, Irina Estrela-Lopis, Zuriñe Baz, Unai Cossío, Jordi Llop
Publikováno v:
Molecules, Vol 24, Iss 19, p 3609 (2019)
Background: Boron Neutron Capture Therapy (BNCT) is a binary approach to cancer therapy that requires accumulation of boron atoms preferentially in tumour cells. This can be achieved by using nanoparticles as boron carriers and taking advantage of th
Externí odkaz:
https://doaj.org/article/c32cceb230c94316b4e4cdef69b72b12
Autor:
Silvia Alonso-de Castro, Emmanuel Ruggiero, Aitor Lekuona Fernández, Unai Cossío, Zuriñe Baz, Dorleta Otaegui, Vanessa Gómez-Vallejo, Daniel Padro, Jordi Llop, Luca Salassa
Publikováno v:
Inorganics, Vol 7, Iss 5, p 60 (2019)
Lanthanide-doped upconverting nanoparticles (UCNPs) transform near infrared light (NIR) into higher-energy UV and visible light by multiphotonic processes. Owing to such unique feature, UCNPs have found application in optical imaging and have been in
Externí odkaz:
https://doaj.org/article/47b6dea9fd0746f08f65724d3907bb71