Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Vanessa Frederick"'
Autor:
Alyssa D Fronk, Miguel A Manzanares, Paulina Zheng, Adam Geier, Kendall Anderson, Shaleigh Stanton, Hasan Zumrut, Sakshi Gera, Robin Munch, Vanessa Frederick, Priyanka Dhingra, Gayatri Arun, Martin Akerman
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 6, Pp 676-701 (2024)
Abstract Splice-switching oligonucleotides (SSOs) are antisense compounds that act directly on pre-mRNA to modulate alternative splicing (AS). This study demonstrates the value that artificial intelligence/machine learning (AI/ML) provides for the id
Externí odkaz:
https://doaj.org/article/af0776e556f747fd855724c15473a6ed
Autor:
Miguel A Manzanares, Priyanka Dhingra, Kendall Anderson, Vanessa Frederick, Adam Geier, Alyssa Casill, Martin Akerman, Gayatri Arun
Publikováno v:
Cancer Research. 82:P5-17
Aberrant splicing is a major hallmark of cancer, affecting tumor progression, metastasis, and therapy resistance. The oncogenic activity of specific cis splicing errors and trans-acting splicing factor misregulation in patient tumors have been demons
Autor:
Alyssa D Fronk, Miguel A Manzanares, Paulina Zheng, Adam Geier, Kendall Anderson, Vanessa Frederick, Shaleigh Smith, Sakshi Gera, Robin Munch, Mahati Are, Priyanka Dhingra, Gayatri Arun, Martin Akerman
This study demonstrates the value that artificial intelligence/machine learning (AI/ML) provides for the identification of novel and verifiable splice-switching oligonucleotide (SSO) targetsin-silico. SSOs are antisense compounds that act directly on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28b9bcb7d19b234dfd363b5fc824d646
https://doi.org/10.1101/2022.10.14.512313
https://doi.org/10.1101/2022.10.14.512313
Autor:
Miguel A. Manzanares, Alyssa Casill, Kendall Anderson, Priyanka Dhingra, Vanessa Frederick, Adam Geier, Martin Akerman, Gayatri Arun
Publikováno v:
Cancer Research. 82:1873-1873
Accumulating evidence highlights aberrant splicing as a disease-driving event in cancer, affecting tumor progression, metastasis, and therapy resistance. Multiple studies have described the tumor-promoting activity of specific aberrant cis-splicing v
Autor:
Miguel A. Manzanares, Dhingra Priyanka, Kendall Anderson, Vanessa Frederick, Adam Geier, Alyssa Casill, Martin Akerman, Gayatri Arun
Publikováno v:
Molecular Cancer Therapeutics. 20:P170-P170
Splicing dysregulation is a major hallmark of cancer, affecting tumor progression, metastasis, and therapy resistance. Multiple studies have demonstrated the oncogenic activity of specific cis splicing errors and trans-acting splicing factor misregul
Autor:
John Shannahan, Vanessa Fredericks
Publikováno v:
The Journal of Classics Teaching, Vol 23, Pp 138-146 (2022)
Relatively little literature specific to the discipline of History aims to translate theory into practice in regard to designing effective online and flipped learning experiences. This article synthesises current literature into practical advice and
Externí odkaz:
https://doaj.org/article/3e4c62f70ced430eb13d67062d8352d5