Výsledky vyhledávání - "Vanessa F.M. Carvalho"

Optimization of composition and obtainment parameters of biocompatible nanoemulsions intended for intraductal administration of piplartine (piperlongumine) and mammary tissue targeting

Autor: Vanessa F.M. Carvalho, Sandra Costa-Fernandez, Edilberto R. Silveira, Giovanna Cassone Salata, Alexandre A. Steiner, Luciana B. Lopes, Gabriel Lima Barros de Araujo, Letícia V. Costa-Lotufo, Marlus Chorilli, Jenyffer Kelly Rocha De Matos

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2019-10-06T05:45:57Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-08-15 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Coor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23193bf481a34dd68f2d4cd48225c286

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Multifunctional nanoemulsions for intraductal delivery as a new platform for local treatment of breast cancer

Autor: Letícia V. Costa-Lotufo, Luciana B. Lopes, Giovanna Cassone Salata, Amanda Migotto, Kelly Ishida, Fernanda Marchetto da Silva, Vanessa F.M. Carvalho, Chao Yun Irene Yan, Alexandre A. Steiner

Publikováno v: Drug Delivery, Vol 25, Iss 1, Pp 654-667 (2018)
Drug Delivery
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Considering that breast cancer usually begins in the lining of the ducts, local drug administration into the ducts could target cancers and pre-tumor lesions locally while reducing systemic adverse effects. In this study, a cationic bioadhesive nanoe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e810f797d32d66a5caaf9bdcc468cd6a

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Development of a method for quantitative determination of the cytotoxic agent piplartine (piperlongumine) in multiple skin layers

Autor: Letícia V. Costa-Lotufo, Edilberto R. Silveira, Vanessa F.M. Carvalho, Luciana B. Lopes, Daniela V. Giacone

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

This study reports the development of a simple and reproducible method, with high rates of recovery, to extract the cytotoxic agent piplartine from skin layers, and a sensitive and rapid UV-HPLC method for its quantification. Considering the potentia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e982ffbea5319bc447c631e576a7fbbf

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Potential of Peptide-Based Enhancers for Transdermal Delivery

Autor: Luciana B. Lopes, Vanessa F.M. Carvalho, Débora P. de Lemos

Publikováno v: Current Pharmaceutical Design. 21:2814-2822

The skin presents several advantages as an administration route, including the possibility of localizing drugs in the tissue and overcoming the first-pass effect. However, its use is limited by the barrier function of the tissue, which is provided ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb62a447022e3d80f77d7ca73a474324
https://doi.org/10.2174/1381612821666150428143243

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Evidence That P-glycoprotein Inhibitor (Elacridar)-Loaded Nanocarriers Improve Epidermal Targeting of an Anticancer Drug via Absorptive Cutaneous Transporters Inhibition

Autor: Luciana B. Lopes, Soraia K.P. Costa, Daniela V. Giacone, Vanessa F.M. Carvalho

Publikováno v: Journal of pharmaceutical sciences. 107(2)

Because P-glycoprotein (P-gp) plays an absorptive role in the skin, its pharmacological inhibition represents a strategy to promote cutaneous localization of anticancer agents that serve as its substrates, improving local efficacy while reducing syst

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ee5903995e5445de8484670473df6d
https://pubmed.ncbi.nlm.nih.gov/28935591

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Co-encapsulation of paclitaxel and C6 ceramide in tributyrin-containing nanocarriers improve co-localization in the skin and potentiate cytotoxic effects in 2D and 3D models

Autor: Letícia V. Costa-Lotufo, Débora P. de Lemos, Silvya Stuchi Maria-Engler, Vanessa F.M. Carvalho, Thalita B. Zanoni, Luciana B. Lopes, Daniela V. Giacone, Amanda Migotto

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Considering that tumor development is generally multifactorial, therapy with a combination of agents capable of potentiating cytotoxic effects is promising. In this study, we co-encapsulated C6 ceramide (0.35%) and paclitaxel (0.50%) in micro and nan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9696368fe8438e6a942e4512942a4c
https://pubmed.ncbi.nlm.nih.gov/28735040

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Transportan in nanocarriers improves skin localization and antitumor activity of paclitaxel

Autor: Dominique Pepe, Melissa Mccall, Vanessa F.M. Carvalho, Débora P. de Lemos, Luciana B. Lopes

Publikováno v: International Journal of Nanomedicine
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Dominique Pepe,1 Vanessa FM Carvalho,2 Melissa McCall,1 Débora P de Lemos,2 Luciana B Lopes1,2 1Department of Pharmaceutical Sciences, Albany College of Pharmacy and Health Sciences, Albany, NY, USA; 2Department of Pharmacology, Institute of Biomedi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d922558f53f186af9b070c155cfc5f98
https://doi.org/10.2147/ijn.s97331

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