Výsledky vyhledávání - "Vanessa F Merino"

Akademický článek

Epigenetic regulation of cell type-specific expression patterns in the human mammary epithelium.

Autor: Reo Maruyama, Sibgat Choudhury, Adam Kowalczyk, Marina Bessarabova, Bryan Beresford-Smith, Thomas Conway, Antony Kaspi, Zhenhua Wu, Tatiana Nikolskaya, Vanessa F Merino, Pang-Kuo Lo, X Shirley Liu, Yuri Nikolsky, Saraswati Sukumar, Izhak Haviv, Kornelia Polyak

Publikováno v: PLoS Genetics, Vol 7, Iss 4, p e1001369 (2011)

Differentiation is an epigenetic program that involves the gradual loss of pluripotency and acquisition of cell type-specific features. Understanding these processes requires genome-wide analysis of epigenetic and gene expression profiles, which have

Externí odkaz: https://doaj.org/article/d4b3642e06ac4e1f994d1ffc664b3e25

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Akademický článek

Induction of cell cycle arrest and inflammatory genes by combined treatment with epigenetic, differentiating, and chemotherapeutic agents in triple-negative breast cancer

Autor: Vanessa F. Merino, Soonweng Cho, Nguyen Nguyen, Helen Sadik, Athira Narayan, Conover Talbot, Leslie Cope, Xian C. Zhou, Zhe Zhang, Balázs Győrffy, Saraswati Sukumar

Publikováno v: Breast Cancer Research, Vol 20, Iss 1, Pp 1-14 (2018)

Abstract Background A combination of entinostat, all-trans retinoic acid, and doxorubicin (EAD) induces cell death and differentiation and causes significant regression of xenografts of triple-negative breast cancer (TNBC). Methods We investigated th

Externí odkaz: https://doaj.org/article/5284294d994a43a388f911c008aff921

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