Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Vanessa E Hennessy"'
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Posttraumatic stress disorder (PTSD) is characterised by dysregulated hypothalamic-pituitary-adrenal axis activity and altered glucocorticoid receptor sensitivity. Early treatment with glucocorticoids may reduce PTSD risk, although the effec
Externí odkaz:
https://doaj.org/article/7cb3d0e17947423f8235111b51ccaedd
Autor:
Ravi K. Das, Grace Gale, Katie Walsh, Vanessa E. Hennessy, Georges Iskandar, Luke A. Mordecai, Brigitta Brandner, Merel Kindt, H. Valerie Curran, Sunjeev K. Kamboj
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Memories linking environmental cues to alcohol reward are involved in the development and maintenance of heavy drinking. Here, the authors show that a single dose of ketamine, given after retrieval of alcohol-reward memories, disrupts the reconsolida
Externí odkaz:
https://doaj.org/article/606a0f7b9edd4aabbf1cf2a46ff7ac24
Autor:
Ravi K. Das, Grace Gale, Katie Walsh, Vanessa E. Hennessy, Georges Iskandar, Luke A. Mordecai, Brigitta Brandner, Merel Kindt, H. Valerie Curran, Sunjeev K. Kamboj
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/c787016e8a7d40eca5c9a8f956710887
Autor:
Ravi K. Das, Luzia Troebinger, Sunjeev K. Kamboj, Giulia Piazza, Georges Iskandar, Vanessa E Hennessy, Hannah Zhao, Emma Cawley
Publikováno v:
International Journal of Neuropsychopharmacology
Background Nitrous oxide (N2O) is an anesthetic gas with both therapeutic and abuse potential. Because N2O is an NMDA receptor (NMDAR) antagonist, its effects are expected to resemble those of the prototypical NMDAR antagonist, ketamine. In this stud
Autor:
Grace Gale, Vanessa E Hennessy, Emily Thomas, Koa Sher Ni, Katie Walsh, L E Stemerding, Ravi K. Das, Sunjeev K. Kamboj
Publikováno v:
Psychological Medicine. 51:2875-2885
BackgroundAlcohol use disorders can be conceptualised as a learned pattern of maladaptive alcohol-consumption behaviours. The memories encoding these behaviours centrally contribute to long-term excessive alcohol consumption and are therefore an impo
Autor:
Brigitta Brandner, Ravi K. Das, Katie Walsh, Grace Gale, H. Valerie Curran, Georges Iskandar, Luke Mordecai, Merel Kindt, Vanessa E Hennessy, Sunjeev K. Kamboj
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
Maladaptive reward memories (MRMs) are involved in the development and maintenance of acquired overconsumption disorders, such as harmful alcohol and drug use. The process of memory reconsolidation - where stored memories become briefly labile upon r
BackgroundAlcohol use disorders can be conceptualised as a learned pattern of maladaptive alcohol-consumption behaviours. The memories encoding these behaviours centrally contribute to long-term excessive alcohol consumption and are a key therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf44871b17acf2bf7a6453a2467033ce
Autor:
Georges Iskandar, Merel Kindt, Valerie Curran, Sunjeev K. Kamboj, Grace Gale, Brigitta Brandner, Ravi K. Das, Katie Walsh, Luke Mordecai, Vanessa E Hennessy
Publikováno v:
Nature Communications, 10:5187. Nature Publishing Group
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Maladaptive reward memories (MRMs) are involved in the development and maintenance of acquired overconsumption disorders, such as harmful alcohol and drug use. The process of memory reconsolidation - where stored memories become briefly labile upon r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0def291244ff1e31a806811a82d5b11e
https://dare.uva.nl/personal/pure/en/publications/ketamine-can-reduce-harmful-drinking-by-pharmacologically-rewriting-drinking-memories(4c260b8a-6a99-4f8e-8c75-bf6c09050e72).html
https://dare.uva.nl/personal/pure/en/publications/ketamine-can-reduce-harmful-drinking-by-pharmacologically-rewriting-drinking-memories(4c260b8a-6a99-4f8e-8c75-bf6c09050e72).html
Publikováno v:
Journal of Visualized Experiments : JoVE
Maladaptive reward memories (MRMs) can become unstable following retrieval under certain conditions, allowing their modification by subsequent new learning. However, robust (well-rehearsed) and chronologically old MRMs, such as those underlying subst