Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Vanessa Del Pozo"'
Autor:
Vanessa Del Pozo, Andrew J. Robles, Shaun D. Fontaine, Qianqian Liu, Joel E. Michalek, Peter J. Houghton, Raushan T. Kurmasheva
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103725- (2022)
Summary: Current therapy is ineffective for relapsed and metastatic Ewing sarcoma (EwS) owing to development of drug resistance. Macromolecular prodrugs potentially lead to lower drug exposure in normal tissues and reduced toxicity. We evaluated the
Externí odkaz:
https://doaj.org/article/a700b93a76404d3aa394fc229d679c04
Autor:
Francisco F. De-Miguel, Carolina Leon-Pinzon, Susana G. Torres-Platas, Vanessa del-Pozo, Guillermo A. Hernández-Mendoza, Dilia Aguirre-Olivas, Bruno Méndez, Sharlen Moore, Celeste Sánchez-Sugía, Marco Antonio García-Aguilera, Alejandro Martínez-Valencia, Guillermo Ramírez-Santiago, J. Miguel Rubí
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Streams of action potentials or long depolarizations evoke a massive exocytosis of transmitters and peptides from the surface of dendrites, axons and cell bodies of different neuron types. Such mode of exocytosis is known as extrasynaptic for occurri
Externí odkaz:
https://doaj.org/article/c54c87672497474abf074f792a571bb0
Autor:
Angelina V. Vaseva, Peter J. Houghton, Kris C. Wood, Myron S. Ignatius, William D. Figg, Cody J. Peer, Sara M. Zimmerman, Anna T. Rogojina, Yidong Chen, Kunal Baxi, Long Wang, Terry J. Shackleford, Craig M. Goodwin, Marielle E. Yohe, Vanessa Del Pozo, Natalia Garcia
Oncogenic RAS signaling is an attractive target for fusion-negative rhabdomyosarcoma (FN-RMS). Our study validates the role of the ERK MAPK effector pathway in mediating RAS dependency in a panel of H/NRASQ61X mutant RMS cells and correlates in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41f8284cff2d8a98fdac0344310698ee
https://doi.org/10.1158/1535-7163.c.6543340
https://doi.org/10.1158/1535-7163.c.6543340
Autor:
Angelina V. Vaseva, Peter J. Houghton, Kris C. Wood, Myron S. Ignatius, William D. Figg, Cody J. Peer, Sara M. Zimmerman, Anna T. Rogojina, Yidong Chen, Kunal Baxi, Long Wang, Terry J. Shackleford, Craig M. Goodwin, Marielle E. Yohe, Vanessa Del Pozo, Natalia Garcia
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d3e61604c7ec0285e0bd4364f173cc
https://doi.org/10.1158/1535-7163.22522342
https://doi.org/10.1158/1535-7163.22522342
Autor:
Angelina V. Vaseva, Peter J. Houghton, Kris C. Wood, Myron S. Ignatius, William D. Figg, Cody J. Peer, Sara M. Zimmerman, Anna T. Rogojina, Yidong Chen, Kunal Baxi, Long Wang, Terry J. Shackleford, Craig M. Goodwin, Marielle E. Yohe, Vanessa Del Pozo, Natalia Garcia
Supplementary figures and legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a5ff6f98e44014e486437be70565a6
https://doi.org/10.1158/1535-7163.22522345.v1
https://doi.org/10.1158/1535-7163.22522345.v1
Autor:
Sara Zimmerman, Terry J Shackleford, Yi Chen, Anna T Rogojina, Kris C. Wood, Angelina V. Vaseva, Cody J. Peer, William D. Figg, Kunal Baxi, Long Wang, Natalia Garcia, Myron S. Ignatius, Craig M. Goodwin, Vanessa Del Pozo, Peter J. Houghton, Marielle E. Yohe
Publikováno v:
Molecular Cancer Therapeutics. 21:170-183
Oncogenic RAS signaling is an attractive target for fusion-negative rhabdomyosarcoma (FN-RMS). Our study validates the role of the ERK MAPK effector pathway in mediating RAS dependency in a panel of H/NRASQ61X mutant RMS cells and correlates in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::473927580cc24e9cdc412c6bd6a92d2f
https://doi.org/10.1158/1535-7163.mct-21-0194
https://doi.org/10.1158/1535-7163.mct-21-0194
Autor:
Vanessa Del Pozo, Andrew J. Robles, Shaun Fontaine, Qianqian Liu, Joel E. Michalek, Peter J. Houghton, Raushan Kurmasheva
Publikováno v:
Cancer Research. 82:1086-1086
Introduction: The Ewing family of sarcomas is the fourth most common highly malignant childhood cancer. Current standard therapy is relatively ineffective for relapsed and metastatic Ewing sarcoma predominantly due to development of resistance to che
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df8ba30c9b074ad31459c00a968699ff
https://doi.org/10.1158/1538-7445.am2022-1086
https://doi.org/10.1158/1538-7445.am2022-1086
Autor:
Natalia, Garcia, Vanessa, Del Pozo, Marielle E, Yohe, Craig M, Goodwin, Terry J, Shackleford, Long, Wang, Kunal, Baxi, Yidong, Chen, Anna T, Rogojina, Sara M, Zimmerman, Cody J, Peer, William D, Figg, Myron S, Ignatius, Kris C, Wood, Peter J, Houghton, Angelina V, Vaseva
Publikováno v:
Mol Cancer Ther
Oncogenic RAS signaling is an attractive target for fusion-negative rhabdomyosarcoma (FN-RMS). Our study validates the role of the ERK MAPK effector pathway in mediating RAS dependency in a panel of H/NRASQ61X-mutant RMS cells and correlates in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb8165807d213ed82a1bf0f5bee4290a
https://pubmed.ncbi.nlm.nih.gov/34737198
https://pubmed.ncbi.nlm.nih.gov/34737198
Autor:
Abhik M Bandyopadhyay, Samson Ghilu, Edward Favours, Vanessa Del Pozo, Raushan T. Kurmasheva, Stephen W. Erickson, Malcolm A. Smith, Gerard McGeehan, Peter J. Houghton, Doris A. Phelps
Publikováno v:
Pediatr Blood Cancer
Background VTP-50469 is a potent inhibitor of the menin-MLL1 interaction and is implicated in signaling downstream of EWSR1-FLI1. Procedure VTP-50469 was evaluated against seven Ewing sarcoma (EwS) xenograft models and in vitro against EwS cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db00accf02389958ed0ca3d7e017003f
https://europepmc.org/articles/PMC10286575/
https://europepmc.org/articles/PMC10286575/
Autor:
Chen-Yin Ou, Michael Toledano, Jonathan T. Grunwald, Anatoly Slepenkin, Domenica Vanessa Del Pozo, Enrico Gratton, Delia F. Tifrea, Kieu Thai La, Jonathan Chong, Yiyan Li, Melody N Toosky, Tam Vu, Ellena M. Peterson, Lingshun Kong, Hemanth Cherukury, Jan Zimak, Susan S. Huang, Timothy J Abram, Byron Shen, Weian Zhao, Louai Labanieh
Publikováno v:
Lab Chip
Lab on a chip, vol 20, iss 3
Lab on a chip, vol 20, iss 3
Sepsis due to antimicrobial resistant pathogens is a major health problem worldwide. The inability to rapidly detect and thus treat bacteria with appropriate agents in the early stages of infections leads to excess morbidity, mortality, and healthcar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7ed023bbe92dc7845f58113581f988
https://pubmed.ncbi.nlm.nih.gov/31872202
https://pubmed.ncbi.nlm.nih.gov/31872202