Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Vanessa Daza-Cajigal"'
Autor:
Miguel G. Uriol-Rivera, Aina Obrador-Mulet, Maria Rosa Juliá, Vanessa Daza-Cajigal, Olga Delgado-Sanchez, Angel Garcia Alvarez, Ana Gomez-Lobon, Paula Carrillo-Garcia, Carlos Saus-Sarrias, Cristina Gómez-Cobo, Daniel Ramis-Cabrer, Joan Gasco Company, Javier Molina-Infante, The Balear IgA Research and Treatment Project
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract There is no established treatment for progressive IgA nephropathy refractory to steroids and immunosuppressant drugs (r-IgAN). Interleukin 17 (IL-17) blockade has garnered interest in immune-mediated diseases involving the gut-kidney axis. H
Externí odkaz:
https://doaj.org/article/ed42bbc09b42496f80578904f9f518a7
Autor:
Vanessa Daza-Cajigal, Marina Segura-Guerrero, María López-Cueto, Ángel Robles-Marhuenda, Carmen Camara, Teresa Gerra-Galán, Ricardo Gómez-de-la-Torre, Carmen L. Avendaño-Monje, Silvia Sánchez-Ramón, María J. Bosque-Lopez, Adriana Quintero-Duarte, María L. Bonet-Vidal, Jaime Pons
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
PurposeThe clinical spectrum of common variable immunodeficiency (CVID) includes predisposition to infections, autoimmune/inflammatory complications and malignancy. Liver disease is developed by a proportion of patients with CVID, but limited evidenc
Externí odkaz:
https://doaj.org/article/057458d5d3214923908fad621ff1e9e1
Autor:
Vanessa Daza-Cajigal, Adriana S. Albuquerque, Dan F. Young, Michael J. Ciancanelli, Dale Moulding, Ivan Angulo, Valentine Jeanne-Julien, Jérémie Rosain, Ekaterina Minskaia, Jean-Laurent Casanova, Stéphanie Boisson-Dupuis, Jacinta Bustamante, Richard E. Randall, Timothy D. McHugh, Adrian J. Thrasher, Siobhan O. Burns
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
PurposeJanus kinase-1 (JAK1) tyrosine kinase mediates signaling from multiple cytokine receptors, including interferon alpha/beta and gamma (IFN-α/β and IFN-γ), which are important for viral and mycobacterial protection respectively. We previously
Externí odkaz:
https://doaj.org/article/374acd87d948410d9f0bc8583651442c
Autor:
Pamela P. Lee, Damián Lobato-Márquez, Nayani Pramanik, Andrea Sirianni, Vanessa Daza-Cajigal, Elizabeth Rivers, Alessia Cavazza, Gerben Bouma, Dale Moulding, Kjell Hultenby, Lisa S. Westerberg, Michael Hollinshead, Yu-Lung Lau, Siobhan O. Burns, Serge Mostowy, Mona Bajaj-Elliott, Adrian J. Thrasher
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Wiskott-Aldrich syndrome protein (WASp) is essential for controlling the cytoskeleton, but its function in innate immunity is unclear. Here the authors show that WASp deficiency is associated with dysregulated septin cage formation, excessive inflamm
Externí odkaz:
https://doaj.org/article/7f189439f64c4318ac3cf0baaa3c3614
Autor:
Davide Eletto, Siobhan O. Burns, Ivan Angulo, Vincent Plagnol, Kimberly C. Gilmour, Frances Henriquez, James Curtis, Miguel Gaspar, Karolin Nowak, Vanessa Daza-Cajigal, Dinakantha Kumararatne, Rainer Doffinger, Adrian J. Thrasher, Sergey Nejentsev
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
JAK1 mediates intracellular signalling from multiple cytokine receptors. Here, Elettoet al. identify JAK1 mutations that disrupt multiple signalling pathways and are associated with primary immunodeficiency, atypical mycobacterial infection susceptib
Externí odkaz:
https://doaj.org/article/d9da547a9dd54017bbcb99a3dd2ffae4
Autor:
Vanessa Daza-Cajigal, Adriana S. Albuquerque, Joanna Pearson, Jennifer Hinley, Andrew S. Mason, Jens Stahlschmidt, Adrian J. Thrasher, Vibhash Mishra, Jennifer Southgate, Siobhan O. Burns
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Inherited Primary Immunodeficiency (PID) disorders are associated with increased risk of malignancy that may relate to impaired antitumor immune responses or a direct role for PID germline mutations in tumorigenesis. We recently identified germline l
Externí odkaz:
https://doaj.org/article/f4a913741e234cc5acc5d4b3790636dc
Autor:
Kerry Dobbs, Giovanna Tabellini, Enrica Calzoni, Ornella Patrizi, Paula Martinez, Silvia Clara Giliani, Daniele Moratto, Waleed Al-Herz, Caterina Cancrini, Morton Cowan, Jacob Bleesing, Claire Booth, David Buchbinder, Siobhan O. Burns, Talal A. Chatila, Janet Chou, Vanessa Daza-Cajigal, Lisa M. Ott de Bruin, Maite Teresa de la Morena, Gigliola Di Matteo, Andrea Finocchi, Raif Geha, Rakesh K. Goyal, Anthony Hayward, Steven Holland, Chiung-Hui Huang, Maria G. Kanariou, Alejandra King, Blanka Kaplan, Anastasiya Kleva, Taco W. Kuijpers, Bee Wah Lee, Vassilios Lougaris, Michel Massaad, Isabelle Meyts, Megan Morsheimer, Benedicte Neven, Sung-Yun Pai, Nima Parvaneh, Alessandro Plebani, Susan Prockop, Ismail Reisli, Jian Yi Soh, Raz Somech, Troy R. Torgerson, Yae-Jean Kim, Jolan E. Walter, Andrew R. Gennery, Sevgi Keles, John P. Manis, Emanuela Marcenaro, Alessandro Moretta, Silvia Parolini, Luigi D. Notarangelo
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Externí odkaz:
https://doaj.org/article/4d51d92b2058445c88fe2aadfd3afece
Autor:
Kerry Dobbs, Giovanna Tabellini, Enrica Calzoni, Ornella Patrizi, Paula Martinez, Silvia Clara Giliani, Daniele Moratto, Waleed Al-Herz, Caterina Cancrini, Morton Cowan, Jacob Bleesing, Claire Booth, David Buchbinder, Siobhan O. Burns, Talal A. Chatila, Janet Chou, Vanessa Daza-Cajigal, Lisa M. Ott de Bruin, Maite Teresa de la Morena, Gigliola Di Matteo, Andrea Finocchi, Raif Geha, Rakesh K. Goyal, Anthony Hayward, Steven Holland, Chiung-Hui Huang, Maria G. Kanariou, Alejandra King, Blanka Kaplan, Anastasiya Kleva, Taco W. Kuijpers, Bee Wah Lee, Vassilios Lougaris, Michel Massaad, Isabelle Meyts, Megan Morsheimer, Benedicte Neven, Sung-Yun Pai, Nima Parvaneh, Alessandro Plebani, Susan Prockop, Ismail Reisli, Jian Yi Soh, Raz Somech, Troy R. Torgerson, Yae-Jaen Kim, Jolan E. Walter, Andrew R. Gennery, Sevgi Keles, John P. Manis, Emanuela Marcenaro, Alessandro Moretta, Silvia Parolini, Luigi D. Notarangelo
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Mutations of the recombinase-activating genes 1 and 2 (RAG1 and RAG2) in humans are associated with a broad range of phenotypes. For patients with severe clinical presentation, hematopoietic stem cell transplantation (HSCT) represents the only curati
Externí odkaz:
https://doaj.org/article/882eccf644f04a0a9df352439dfff1bd