Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Vanessa Cossu"'
Autor:
Sonia Carta, Vanessa Cossu, Francesca Vitale, Matteo Bauckneht, Maddalena Ghelardoni, Anna Maria Orengo, Serena Losacco, Daniela Gaglio, Silvia Bruno, Sabrina Chiesa, Silvia Ravera, Gianmario Sambuceti, Cecilia Marini
Publikováno v:
Heliyon, Vol 10, Iss 19, Pp e38718- (2024)
Cancer growth requires high amount of nicotinamide adenine dinucleotide phosphate (NADPH) to feed the anabolic reactions and preserve the redox balance. NADPH level is largely preserved by the oxidative arm of the pentose phosphate pathway (PPP). Her
Externí odkaz:
https://doaj.org/article/dd6e2cf5aebb49fb8baef7a33a24872e
Autor:
Sonia Carta, Maddalena Ghelardoni, Francesca Vitale, Silvia Ravera, Vanessa Cossu, Nadia Bertola, Serena Losacco, Jonathan Martinelli, Edoardo Dighero, Mattia Riondato, Anna Maria Orengo, Matteo Bauckneht, Sabrina Chiesa, Gianmario Sambuceti, Cecilia Marini
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 7, p 251 (2024)
Background: Selective deprivation of glutamine has been shown to accelerate the generation of reactive oxygen species (ROS) and to impair the activity of a specific pentose phosphate pathway (PPP) located within the endoplasmic reticulum (ER). The co
Externí odkaz:
https://doaj.org/article/21bf04acc7884dafb72bc80d59567d52
Autor:
Matteo Bauckneht, Cecilia Marini, Vanessa Cossu, Cristina Campi, Mattia Riondato, Silvia Bruno, Anna Maria Orengo, Francesca Vitale, Sonia Carta, Silvia Chiola, Sabrina Chiesa, Alberto Miceli, Francesca D’Amico, Giuseppe Fornarini, Carlo Terrone, Michele Piana, Silvia Morbelli, Alessio Signori, Paola Barboro, Gianmario Sambuceti
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background Positron Emission Tomography (PET) imaging with Prostate-Specific Membrane Antigen (PSMA) and Fluorodeoxyglucose (FDG) represent promising biomarkers for risk-stratification of Prostate Cancer (PCa). We verified whether the expres
Externí odkaz:
https://doaj.org/article/6cd832d06026417086a422455d891893
Autor:
Enrica Balza, Sebastiano Carlone, Sonia Carta, Patrizia Piccioli, Vanessa Cossu, Cecilia Marini, Gianmario Sambuceti, Anna Rubartelli, Patrizia Castellani
Publikováno v:
Cancer Medicine, Vol 11, Iss 1, Pp 183-193 (2022)
Abstract Triple negative breast cancers (TNBCs) are very aggressive and have a poor prognosis due to lack of efficacious therapies. The only effective treatment is chemotherapy that however is frequently hindered by the occurrence of drug resistance.
Externí odkaz:
https://doaj.org/article/01a314b1254e4be3aa2b0995e978c641
Autor:
Sonia Spinelli, Lucrezia Guida, Mario Passalacqua, Mirko Magnone, Vanessa Cossu, Gianmario Sambuceti, Cecilia Marini, Laura Sturla, Elena Zocchi
Publikováno v:
Antioxidants, Vol 12, Iss 9, p 1692 (2023)
The cross-kingdom stress hormone abscisic acid (ABA) and its mammalian receptors LANCL1 and LANCL2 regulate the response of cardiomyocytes to hypoxia by activating NO generation. The overexpression of LANCL1/2 increases transcription, phosphorylation
Externí odkaz:
https://doaj.org/article/4dc2e87cc10b4478ab8cb3949999c275
Autor:
Vanessa Cossu, Marcella Bonanomi, Matteo Bauckneht, Silvia Ravera, Nicole Righi, Alberto Miceli, Silvia Morbelli, Anna Maria Orengo, Patrizia Piccioli, Silvia Bruno, Daniela Gaglio, Gianmario Sambuceti, Cecilia Marini
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Abstract The relevant role of pentose phosphate pathway (PPP) in cancer metabolic reprogramming has been usually outlined by studying glucose-6-phosphate dehydrogenase (G6PD). However, recent evidence suggests an unexpected role for a less characteri
Externí odkaz:
https://doaj.org/article/dcc05ac72c4a498785c00b45a4a47e1d
Autor:
Cecilia Marini, Vanessa Cossu, Tiziana Bonifacino, Matteo Bauckneht, Carola Torazza, Silvia Bruno, Patrizia Castellani, Silvia Ravera, Marco Milanese, Consuelo Venturi, Sebastiano Carlone, Patrizia Piccioli, Laura Emionite, Silvia Morbelli, Anna Maria Orengo, Maria Isabella Donegani, Alberto Miceli, Stefano Raffa, Stefano Marra, Alessio Signori, Katia Cortese, Federica Grillo, Roberto Fiocca, Giambattista Bonanno, Gianmario Sambuceti
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-16 (2020)
Abstract Background We recently reported that enhanced [18F]-fluorodeoxyglucose (FDG) uptake in skeletal muscles predicts disease aggressiveness in patients with amyotrophic lateral sclerosis (ALS). The present experimental study aimed to assess whet
Externí odkaz:
https://doaj.org/article/6776dde55de34117aebe900fc801c0e9
Autor:
Matteo Bauckneht, Rita Lai, Alberto Miceli, Daniela Schenone, Vanessa Cossu, Maria Isabella Donegani, Stefano Raffa, Anna Borra, Stefano Marra, Cristina Campi, Annamaria Orengo, Anna Maria Massone, Alberto Tagliafico, Claudia Caponnetto, Corrado Cabona, Angelina Cistaro, Adriano Chiò, Silvia Morbelli, Flavio Nobili, Gianmario Sambuceti, Michele Piana, Cecilia Marini
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Purpose Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease leading to neuromuscular palsy and death. We propose a computational approach to [18F]-fluorodeoxyglucose (FDG) PET/CT images to analyze the structure and metabolic p
Externí odkaz:
https://doaj.org/article/86aba4cbc2844679a68dc65ae94bce39
Autor:
Matteo Bauckneht, Vanessa Cossu, Patrizia Castellani, Patrizia Piccioli, Anna Maria Orengo, Laura Emionite, Francesco Di Giulio, Maria Isabella Donegani, Alberto Miceli, Stefano Raffa, Anna Borra, Selene Capitanio, Silvia Morbelli, Giacomo Caviglia, Silvia Bruno, Silvia Ravera, Davide Maggi, Gianmario Sambuceti, Cecilia Marini
Publikováno v:
Molecular Metabolism, Vol 31, Iss , Pp 98-108 (2020)
Objectives: The present study aims to verify the relationship between glucose consumption and uptake of 18F-2-deoxy-glucose (FDG) in the skeletal muscle (SM) of experimental models of streptozotocin-induced diabetes mellitus (STZ-DM). Methods: The st
Externí odkaz:
https://doaj.org/article/7e16363c210046f9aabb89e69b04f921
Autor:
Francesco Lanfranchi, Francesca D'Amico, Stefano Raffa, Michele Pennone, Maria Isabella Donegani, Alberto Miceli, Silvia Chiola, Sara Maggio, Carlo Delucchi, Vanessa Cossu, Silvia Morbelli, Matteo Bauckneht, Gianmario Sambuceti, Cecilia Marini
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Objective: Sympathetic nervous system (SNS) reaction to exercise is gender dependent. Nevertheless, clinically applicable methods to identify this difference are still missing. An organ largely sensitive to SNS is the spleen whose response to exercis
Externí odkaz:
https://doaj.org/article/6af20507e5dd44769854986ad03cf093