An international observational study assessing conservative management in hemorrhoidal disease: results of CHORALIS (aCute HemORrhoidal disease evALuation International Study)

Autor: Philippe Godeberge, Zoltan Csiki, Mykhailo Zakharash, Elly Nyaim Opot, Yuri A Shelygin, Trung Tin Nguyen, Ashraf Amir, Ibrahima Konate, Moses Momoh, Joanna Chirol, Vanessa Blanc-Guillemaud, Ren Donglin

Publikováno v: Journal of Comparative Effectiveness Research, Vol 13, Iss 10 (2024)

Aim: Real-world evidence on the management of hemorrhoidal disease (HD) is limited. This international study collected clinical practice data on the effectiveness of conservative treatments for acute HD on symptoms and quality of life (QoL), provid

Externí odkaz: https://doaj.org/article/f68d8789acb142e384f2461ca83b1c75

Generalizability of randomized controlled trials in heart failure with reduced ejection fraction

Autor: Maureen Cronin, Claire Baudier, Megan Molnar, Marinus J.C. Eijkemans, Folkert W. Asselbergs, Jasper J. Brugts, Yvonne Mei Fong Lim, Ilonca Vaartjes, Arno W. Hoes, Alicia Uijl, Vanessa Blanc-Guillemaud, Gianluigi Savarese, Christoph Gerlinger, Diederick E. Grobbee, Stefan Koudstaal, Hans-Peter Brunner-La Rocca, Tomasz Dyszynski, Lars Lund, Fabrice Couvelard, Eleni Vradi, Benoit Tyl, Kiliana Suzart-Woischnik, Sandra Waechter

Publikováno v: European Heart Journal-Quality of Care and Clinical Outcomes, 8(7), 761-769. Oxford University Press
European Heart Journal
Lim, Y M F, Molnar, M, Vaartjes, I, Savarese, G, Eijkemans, M J C, Uijl, A, Vradi, E, Suzart-Woischnik, K, Brugts, J J, Brunner-la Rocca, H-P, Blanc-Guillemaud, V, Couvelard, F, Baudier, C, Dyszynski, T, Waechter, S, Lund, L H, Hoes, A W, Tyl, B, Asselbergs, F W, Gerlinger, C, Grobbee, D E, Cronin, M & Koudstaal, S 2022, ' Generalizability of randomized controlled trials in heart failure with reduced ejection fraction ', European Heart Journal-Quality of Care and Clinical Outcomes, vol. 8, no. 7, pp. 761-769 . https://doi.org/10.1093/ehjqcco/qcab070
European heart journal. Quality of care & clinical outcomes, 8(7). Oxford University Press
European heart journal. Quality of care & clinical outcomes, 8(7), 761-769. Oxford University Press

Background Heart failure (HF) trials have stringent inclusion and exclusion criteria, but limited data exist regarding generalizability of trials. We compared patient characteristics and outcomes between patients with HF and reduced ejection fraction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a41f3d97613f038aff102862804f0b
https://doi.org/10.1093/ehjqcco/qcab070

Time course of microvalve pathophysiology in high pressure low flow model of venous insufficiency and the role of micronized purified flavonoid fraction

Autor: Vanessa Blanc-Guillemaud, Fatima Z. G. A. Cyrino, Eliete Bouskela

Publikováno v: International angiology : a journal of the International Union of Angiology. 40(5)

BACKGROUND The aim of this study was to characterize, in an experimental model, the mechanisms involved in the initiation of venous insufficiency at the level of microvenous valve and whether they can be influenced by early treatment with micronized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::620c60a86a90e7fb7cd2723cf29086e7
https://pubmed.ncbi.nlm.nih.gov/34282857

Protective Effects of Micronized Purified Flavonoid Fraction (MPFF) on a Novel Experimental Model of Chronic Venous Hypertension

Autor: Maria das Graças Coelho de Souza, Vanessa Blanc-Guillemaud, Jorge José de Carvalho, Eliete Bouskela, Fatima Zga Cyrino

Publikováno v: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery. 55(5)

OBJECTIVES To assess protective effects of micronized purified flavonoid fraction (MPFF) on microcirculation in an original chronic model of hind limb venous hypertension with low blood flow in small animals. METHODS Vein ligatures were performed on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35d2968e766f4d16ed86173410675e7c
https://pubmed.ncbi.nlm.nih.gov/29588131

Terutroban, a Thromboxane/Prostaglandin Endoperoxide Receptor Antagonist, Increases Survival in Stroke-Prone Rats by Preventing Systemic Inflammation and Endothelial Dysfunction: Comparison with Aspirin and Rosuvastatin

Autor: Luigi Sironi, Elena Nobili, Elena Tremoli, Alice Pignieri, Cristina Banfi, Maura Brioschi, Anita Gianella, Uliano Guerrini, Laurence Lerond, Paolo Gelosa, R. Ballerio, Laura Castiglioni, Vanessa Blanc-Guillemaud

Publikováno v: Journal of Pharmacology and Experimental Therapeutics. 334:199-205

This study investigated the efficacy of terutroban, a specific thromboxane/prostaglandin endoperoxide receptor antagonist, on stroke incidence in spontaneously hypertensive strokeprone rats (SHRSP). The effects of terutroban were compared with those

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd0b1b54f83f19a22360803d0120935
https://doi.org/10.1124/jpet.110.165787