Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Vanessa B. Sequeira"'
Autor:
Peter W. Gunning, Timothy P. Cripe, Wolfgang Weninger, Ian Dixon, Vivienne E. Reeve, David Winlaw, Edna C. Hardeman, Stephen J. Palmer, Galina Schevzov, Adam McCluskey, Timothy A. Hill, Thomas Fath, Munif Allanson, Tanya L. Butler, Vanessa B. Sequeira, Paula R.B.B. Nascimento, Jun Zeng, Herbert Treutlein, Gregg Kottyan, Melissa Desouza, Teresa Bonello, Nikolas K. Haass, Justine R. Stehn
The actin cytoskeleton is a potentially vulnerable property of cancer cells, yet chemotherapeutic targeting attempts have been hampered by unacceptable toxicity. In this study, we have shown that it is possible to disrupt specific actin filament popu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26aeb0a4df2ed1d4a6bcc28ad80f73a4
https://doi.org/10.1158/0008-5472.c.6505788
https://doi.org/10.1158/0008-5472.c.6505788
Autor:
Peter W. Gunning, Timothy P. Cripe, Wolfgang Weninger, Ian Dixon, Vivienne E. Reeve, David Winlaw, Edna C. Hardeman, Stephen J. Palmer, Galina Schevzov, Adam McCluskey, Timothy A. Hill, Thomas Fath, Munif Allanson, Tanya L. Butler, Vanessa B. Sequeira, Paula R.B.B. Nascimento, Jun Zeng, Herbert Treutlein, Gregg Kottyan, Melissa Desouza, Teresa Bonello, Nikolas K. Haass, Justine R. Stehn
PDF file - 1137K, Supplementary Figure 1: Tropomyosin siRNA knockdown is isoform specific and does not result in any compensation. Supplementary Figure 2: TR100 nullifies the impact of Tm5NM1 on actin filament depolymerization kinetics. Supplementary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a67470c9b0ede032a904e3d83d8998e
https://doi.org/10.1158/0008-5472.22401237
https://doi.org/10.1158/0008-5472.22401237
Autor:
Warusavithana Gunawardena Manori De Silva, Rebecca S. Mason, Gary M. Halliday, A. Dilley, Vanessa B. Sequeira, Mark S. Rybchyn, Katie M. Dixon, Bianca Y McCarthy
Publikováno v:
Journal of Investigative Dermatology. 138:1146-1156
Inadequately repaired post-UV DNA damage results in skin cancers. DNA repair requires energy but skin cells have limited capacity to produce energy after UV insult. We examined whether energy supply is important for DNA repair after UV exposure, in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::844f9ddbf9d10ddb99225999bf33b868
https://doi.org/10.1016/j.jid.2017.11.037
https://doi.org/10.1016/j.jid.2017.11.037
Autor:
Anthony J. Kee, Vanessa B. Sequeira, Peter W. Gunning, Elizabeth A. Musgrove, Benjamin T. Kile, Bin Wang, Thomas Fath, Christine A. Lucas, Galina Schevzov, Edna C. Hardeman, Jason D. Coombes, Rony Seger, Alexandra Cretu, Justine R. Stehn, Richard K. Assoian, Jeff Hook, Tamar Hanoch, Irina Pleines
Publikováno v:
Molecular Biology of the Cell
Tropomyosin Tm5NM1 regulates cell proliferation and organ size. It mediates this effect by regulating the interaction of pERK and Imp7, leading to the regulation of pERK nuclear translocation. This demonstrates a role for a specific population of act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0eaefb18ac98351e9568cc50c89e79b
https://doi.org/10.1091/mbc.e14-10-1453
https://doi.org/10.1091/mbc.e14-10-1453
Autor:
Ian Dixon, Vanessa B. Sequeira, Gregg Kottyan, Thomas Fath, Jun Zeng, Timothy P. Cripe, Vivienne E. Reeve, Tanya L. Butler, Edna C. Hardeman, David S. Winlaw, Galina Schevzov, Melissa Desouza, Paula R. B. B. Nascimento, Stephen J. Palmer, Timothy A. Hill, Adam McCluskey, Herbert R. Treutlein, Peter W. Gunning, Munif Allanson, Nikolas K. Haass, Justine R. Stehn, Wolfgang Weninger, Theresa Bonello
Publikováno v:
Cancer Research. 73:5169-5182
The actin cytoskeleton is a potentially vulnerable property of cancer cells, yet chemotherapeutic targeting attempts have been hampered by unacceptable toxicity. In this study, we have shown that it is possible to disrupt specific actin filament popu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::545b1b013ef30ef626cb7dd9fd014836
https://doi.org/10.1158/0008-5472.can-12-4501
https://doi.org/10.1158/0008-5472.can-12-4501
Autor:
Eric J. Song, Katie M. Dixon, Vanessa B. Sequeira, Sally E. Carter, Clare Gordon-Thomson, Wannit Tongkao-on, Mark S. Rybchyn, Rebecca S. Mason
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 14, Iss 1, Pp 1964-1977 (2013)
International Journal of Molecular Sciences, Vol 14, Iss 1, Pp 1964-1977 (2013)
Exposure to sunlight is the major cause of skin cancer. Ultraviolet radiation (UV) from the sun causes damage to DNA by direct absorption and can cause skin cell death. UV also causes production of reactive oxygen species that may interact with DNA t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::862622d11a9b8d8170d6deb242733838
https://doi.org/10.3390/ijms14011964
https://doi.org/10.3390/ijms14011964
Autor:
Rebecca S. Mason, Clare Gordon-Thomson, Vivienne E. Reeve, Wannit Tongkao-on, Eric J. Song, Tan Luu, Katie M. Dixon, Vanessa B. Sequeira, Sally E. Carter
Publikováno v:
Dermato-endocrinology
As skin cancer is one of the most costly health issues in many countries, particularly in Australia, the possibility that vitamin D compounds might contribute to prevention of this disease is becoming increasingly more attractive to researchers and h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c154665c58dade05fb948d76061e2db
https://doi.org/10.4161/derm.23939
https://doi.org/10.4161/derm.23939
Autor:
Katie M. Dixon, Vanessa B. Sequeira, Rebecca S. Mason, Ritu Mohan, Shivashni Deo, Gary H. Posner
Publikováno v:
Photochemical & Photobiological Sciences. 11:1825-1830
We have previously demonstrated that the active vitamin D hormone, 1α,25-dihydroxyvitamin D3 (1,25(OH)(2)D(3)) and a cis-locked non-genomic analogue, protect skin cells from ultraviolet radiation (UV)-induced skin cell loss, DNA damage, immunosuppre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cb6a544a63f1085fbff57b1cceb038d
https://doi.org/10.1039/c2pp25208b
https://doi.org/10.1039/c2pp25208b
Autor:
Vivienne E. Reeve, Clare Gordon-Thomson, Peter J. Malloy, Mark S. Rybchyn, Vanessa B. Sequeira, Rebecca S. Mason, Gary M. Halliday, Anthony W. Norman, David Feldman, Wannit Tongkao-on, Ilka Nemere
Publikováno v:
Molecular Endocrinology. 26:574-582
UV radiation (UVR) is essential for formation of vitamin D(3), which can be hydroxylated locally in the skin to 1α,25-dihydroxyvitamin D(3) [1,25-(OH)(2)D(3)]. Recent studies implicate 1,25-(OH)(2)D(3) in reduction of UVR-induced DNA damage, particu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fad8c4edcda12e4e14ce47d7a581bc2c
https://doi.org/10.1210/me.2011-1161
https://doi.org/10.1210/me.2011-1161
Autor:
Vivienne E. Reeve, Katie M. Dixon, Anthony W. Norman, Rebecca S. Mason, Vanessa B. Sequeira, Ritu Mohan, Mark S. Rybchyn, Gary M. Halliday
Publikováno v:
Cancer Prevention Research. 4:1485-1494
Exposure to ultraviolet radiation (UVR) can lead to a range of deleterious responses in the skin. An important form of damage is the DNA photolesion cyclobutane pyrimidine dimer (CPD). CPDs can be highly mutagenic if not repaired prior to cell divisi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1364937947a2954258ef919d34dabe
https://doi.org/10.1158/1940-6207.capr-11-0165
https://doi.org/10.1158/1940-6207.capr-11-0165