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of 8
pro vyhledávání: '"Vanessa, Plouffe"'
Autor:
Vanessa Plouffe, Nguyen-Vi Mohamed, Jessica Rivest-McGraw, Johanne Bertrand, Michel Lauzon, Nicole Leclerc
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36873 (2012)
It is well established that tau pathology propagates in a predictable manner in Alzheimer's disease (AD). Moreover, tau accumulates in the cerebrospinal fluid (CSF) of AD's patients. The mechanisms underlying the propagation of tau pathology and its
Externí odkaz:
https://doaj.org/article/b45e93e0ccc849088cd3a00359c783f9
Autor:
Gaudeline Rémillard-Labrosse, Nicole Leclerc, Nguyen-Vi Mohamed, Vanessa Plouffe, Emmanuel Planel
Publikováno v:
Scientific Reports
Recent studies have demonstrated that human tau can be secreted by neurons and non-neuronal cells, an event linked to the propagation of tau pathology in the brain. In the present study, we confirmed that under physiological conditions, one tau-posit
Publikováno v:
The European journal of neuroscience. 37(12)
It is well documented that neurofibrillary tangles composed of aggregated tau protein propagate in a predictable pattern in Alzheimer's disease (AD). The mechanisms underlying the propagation of tau pathology are still poorly understood. Recent studi
Autor:
Nguyen-Vi Mohamed, Vanessa Plouffe, Jessica Rivest-McGraw, Johanne Bertrand, Michel Lauzon, Nicole Leclerc
Publikováno v:
Alzheimer's & Dementia. 8
Publikováno v:
Journal of Neurochemistry.
J. Neurochem. (2010) 114, 1353–1367. Abstract In tauopathies including Alzheimer’s disease, the axonal microtubule-associated protein tau becomes hyperphosphorylated at pathological epitopes and accumulates in the somato-dendritic compartment. Ho
Autor:
Johanne, Bertrand, Patrick, Sénéchal, Mathieu, Zummo-Soucy, Vanessa, Plouffe, Nicole, Leclerc
Publikováno v:
Journal of neurochemistry. 114(5)
In tauopathies including Alzheimer's disease, the axonal microtubule-associated protein tau becomes hyperphosphorylated at pathological epitopes and accumulates in the somato-dendritic compartment. However, it remains unclear whether tau becomes phos
Publikováno v:
Neuroscience. 168(2)
Tau, an axonal microtubule-associated protein, becomes hyperphosphorylated in several neurodegenerative diseases including Alzheimer disease (AD). In AD brain, tau is phosphorylated at pathological multiple-site epitopes recognized by the antibodies
Autor:
Nguyen-Vi Mohamed, Nicole Leclerc, Vanessa Plouffe, Johanne Bertrand, Jessica Rivest-McGraw, Michel Lauzon
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 5, p e36873 (2012)
PLoS ONE, Vol 7, Iss 5, p e36873 (2012)
It is well established that tau pathology propagates in a predictable manner in Alzheimer's disease (AD). Moreover, tau accumulates in the cerebrospinal fluid (CSF) of AD's patients. The mechanisms underlying the propagation of tau pathology and its