Controlling the lag-time and release kinetics of press-coated tablets using process parameters and tablet geometry

Autor: Léo, Picart, Vincent, Mazel, Aline, Moulin, Vanessa, Bourgeaux, Pierre, Tchoreloff

Publikováno v: International Journal of Pharmaceutics. 627:122252

Press-coated tablets are an advantageous technology to achieve delayed releases of active ingredients. They are characterized by a core-shell structure, that makes it possible to tune the lag-time and release kinetics in order to meet the chronothera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a90e839831211729fc02aff928fa3999
https://doi.org/10.1016/j.ijpharm.2022.122252

Liquid chromatography coupled to tandem mass spectrometry for the analysis of inositol hexaphosphate after solid-phase extraction

Autor: Blandine Rougemont, Jérôme Lemoine, Catherine Fonbonne, Arnaud Salvador, Vanessa Bourgeaux

Publikováno v: Journal of Liquid Chromatography and Related Technologies
Journal of Liquid Chromatography and Related Technologies, Taylor & Francis: STM, Behavioural Science and Public Health Titles, 2016, 39 (8), pp.408-414. ⟨10.1080/10826076.2016.1169427⟩

International audience; Inositol hexaphosphate, a naturally occurring component in cereals and plants, is the main reserve and principal carrier of phosphate. Inositol hexaphosphate is also found in biological fluids such as urine, plasma, or whole b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::766eac4336ad03a6e65b8a3717ebb23b
https://doi.org/10.1080/10826076.2016.1169427

Abstract 2258: Erymethionase (methionine-gamma-lyase encapsulated into red blood cells) potentiates anti-PD-1 therapy in TNBC syngeneic mouse model

Autor: Karine Sénéchal, Sylvie Maubant, Marie Leblanc, Séverine Ciré, Fanny Gallix, Aurély Andrivon, Olivier Duchamp, Fabrice Viviani, Françoise Horand, Alexander Scheer, Vanessa BOURGEAUX

Publikováno v: Cancer Research. 79:2258-2258

Background : Anti-PD-1 immunotherapy, although efficient in several cancer indications; has shown some limitations due to the appearance of resistance mechanisms. More specifically, the overexpression of A2A receptor (adenosine receptor) on the surfa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dff311883fa2c33db73f47563049efad
https://doi.org/10.1158/1538-7445.am2019-2258

International seminar on the red blood cells as vehicles for drugs

Autor: Kurt C Gunter, Françoise Horand, Robert S. Franco, José M. Lanao, Emmanuelle Dufour, Elena I. Sinauridze, Alice Banz, Olexii A Skorokhod, Elena Kosenko, Yann Godfrin, Victor Vitvitsky, Vanessa Bourgeaux, Bridget E. Bax

Publikováno v: Expert Opinion on Biological Therapy. 12:127-133

The first human transfusion was performed by the pioneer Dr Jean-Baptiste Denis in France in 1667 and now, three centuries later, around 50 millions blood units are transfused every year, saving millions of lives. Today, there is a new application fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::818b2ab60470131b366373e187bc8390
https://doi.org/10.1517/14712598.2012.631909

Inositol hexaphosphate-loaded red blood cells prevent in vitro sickling

Autor: Dominique Rigal, Gaëlle Delcambre, Anne-Marie Chevrier, Vanessa Bourgeaux, Olivier Hequet, Yannick Campion, Yann Godfrin

Publikováno v: Transfusion. 50:2176-2184

BACKGROUND: Hypoxia is a major cause of painful vaso-occlusive crisis in sickle cell disease (SCD). Simple transfusion and red blood cell (RBC) exchange are commonly used as preventive therapies whose aim is to dilute hemoglobin (Hb)S-containing RBCs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b0abb4221569f08c86680905782c38ce
https://doi.org/10.1111/j.1537-2995.2010.02663.x