Effect of ketotifen fumarate on experimental autoimmune orchitis and torsion of the spermatic cord

Autor: Diego Moreno, Cristian M Sobarzo, Livia Lustig, Marcelo G Rodríguez Peña, Vanesa Anabella Guazzone

Publikováno v: Asian Journal of Andrology, Vol 22, Iss 1, Pp 112-117 (2020)

The aim of this work was to study effects of ketotifen fumarate (KF) on prevention of tissue damage in testes of rats with experimental autoimmune orchitis (EAO) and on the contralateral testis in a model of prolonged testicular cord torsion (TCT). R

Externí odkaz: https://doaj.org/article/bd36ec66cbb84ddbaa979e63ae9285a4

Relevance of angiogenesis in autoimmune testis inflammation

Autor: Vanesa Anabella Guazzone, Cristian Marcelo Sobarzo, Livia Lustig, Gisela Soledad Gualdoni, Cecilia Valeria Pérez, Luis Alberto Haro Durand, Patricia Verónica Jacobo, María Susana Theas

Publikováno v: Molecular human reproduction. 27(2)

Experimental autoimmune orchitis (EAO) is a useful model to study organ-specific autoimmunity and chronic testicular inflammation. This model reflects testicular pathological changes reported in immunological infertility in men. Progression of EAO in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73cbb760a36789acbaa0e62f9646abd5
https://pubmed.ncbi.nlm.nih.gov/33313783

Role of indoleamine 2,3-dioxygenase in testicular immune-privilege

Autor: Patricia Verónica Jacobo, Cecilia Valeria Pérez, Monica Beatriz Frungieri, Livia Lustig, Cristian Marcelo Sobarzo, Christian Höcht, Marcelo Hill, Vanesa Anabella Guazzone, Maria Eugenia Matzkin, Ignacio Anegon, Gisela Soledad Gualdoni

Publikováno v: Scientific Reports
Scientific Reports, 2019, 9 (1), pp.15919. ⟨10.1038/s41598-019-52192-8⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Male meiotic germ cell including the spermatozoa represent a great challenge to the immune system, as they appear long after the establishment of normal immune tolerance mechanisms. The capacity of the testes to tolerate autoantigenic germ cells as w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb5ed2a24542f378976c2a99d4e9971
https://www.hal.inserm.fr/inserm-02375586

Impaired male fertility and abnormal epididymal epithelium differentiation in mice lacking CRISP1 and CRISP4

Autor: Mariana Weigel Muñoz, Sylvie Breton, Masahito Ikawa, Patricia S. Cuasnicú, Livia Lustig, Maria A. Battistone, Vanesa Anabella Guazzone, Guillermo Carvajal, Nicolás Gastón Brukman, Miyata Haruhiko

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-19 (2018)
Scientific Reports
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Carvajal, G., Brukman, N.G., Weigel Muñoz, M. et al. Impaired male fertility and abnormal epididymal epithelium differentiation in mice lacking CRISP1 and CRISP4. Sci Rep 8, 17531 (2018). https://doi.org/10.1038/s41598-018-35719-3
Epididymal Cy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e585ace584e75467c2fdf39f9b4f24
https://www.nature.com/articles/s41598-018-35719-3

Up regulation of nitric oxide synthase–nitric oxide system in the testis of rats undergoing autoimmune orchitis

Autor: María Susana Theas, Patricia Verónica Jacobo, Livia Lustig, Cecilia Valeria Pérez, S. Jarazo-Dietrich, Vanesa Anabella Guazzone

Publikováno v: Immunobiology. 217:778-787

Background Male reproductive tract infection and inflammation are important aetiological factors of infertility. Experimental Autoimmune Orchitis (EAO) is a model of chronic inflammation useful to study mechanisms of inflammatory reactions leading to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f59717a5879a03a265e065a1a1fd351
https://doi.org/10.1016/j.imbio.2012.04.007