Výsledky vyhledávání - "Vanechten, J."

Cytogenetics of primary testicular nonseminoma, residual mature teratoma, and growing teratoma lesion in individual patients

Autor: vanEchten, J, Sleijfer, DT, Wiersema, J, deJong, B, Schraffordt Koops, H.

Publikováno v: Cancer Genetics and Cytogenetics, 96(1), 1-6. ELSEVIER SCIENCE INC

Residual mature teratoma (RMT) is often left behind when metastases of primary nonseminomatous germ cell tumors (NSs) are treated with chemotherapy. RMT is composed of fully differentiated somatic tissue. A growing teratoma (GTE) lesion may occur aft

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::59e874348a84817a8ef85a5ce23167a7
https://research.rug.nl/en/publications/1d01b99e-87b0-4713-850e-de8c06b6003f

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Comparative genomic hybridization of germ cell tumors of the adult testis: Confirmation of karyotypic findings and identification of a 12p-amplicon

Autor: Mostert, MMC, vandePol, M, Weghuis, DO, Suijkerbuijk, RF, vanKessel, AG, vanEchten, J, Looijenga, LHJ

Publikováno v: Cancer Genetics and Cytogenetics, 89(2), 146-152. ELSEVIER SCIENCE INC

Comparative genomic hybridization (CGH) was carried out on 15 primary testicular germ cell tumors (TGCT) of adolescents and adults and two metastatic residual tumors after chemotherapeutic treatment. The results were compared with karyotypic data obt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::124554a5a232c09a1ddba4b135110322
https://research.rug.nl/en/publications/62dca74f-2b9f-44e1-b507-f1f1c62d7cb9

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Mixed testicular germ cell tumors: Monoclonal or polyclonal

Autor: vanEchten, J, Looijenga, LHJ, Sleijfer, DT, deJong, B, Schraffordt Koops, H., Dam, A.

Publikováno v: Modern Pathology, 9(4), 371-374. Nature Publishing Group

Testicular germ cell tumors (TGCT) of adolescents and adults are, for clinical and pathological reasons, divided in seminomas (SE) and nonseminomatous germ cell tumors (NS). Whether and to what degree these two entities are pathogenetically related i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::85c2e7ac5519ffe9cf20ea1b8152c8ad
https://research.rug.nl/en/publications/58bb35d9-0549-4be1-aa15-514b3e1ce528

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Fluorescence in situ hybridization-based approaches for detection of 12p overrepresentation, in particular i(12p), in cell lines of human testicular germ cell tumors of adults

Autor: Mostert, MMC, vandePol, M, vanEchten, J, Weghuis, DO, vanKessel, AG, Looijenga, LHJ

Publikováno v: Cancer Genetics and Cytogenetics, 87(2), 95-102. ELSEVIER SCIENCE INC

Overrepresentation of the short arm of chromosome 12 is frequently detected in human testicular germ cell tumors of adolescents and adults (TGCT). This overrepresentation mostly results from the formation of an isochromosome: i(12p). Whether the over

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::ad95cb92e81372cb8d6573318bd379bb
https://research.rug.nl/en/publications/8fe28e21-a688-4324-a0e3-22e513acb1dc

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DEFINITION OF A NEW ENTITY OF MALIGNANT EXTRAGONADAL GERM-CELL TUMORS

Autor: VANECHTEN, J, DEJONG, B, SINKE, RJ, WEGHUIS, DO, SLEIJFER, DT, OOSTERHUIS, JW

Publikováno v: GENES CHROMOSOMES & CANCER, 12(1), 8-15. Wiley

Two malignant extragonadal germ cell tumors are reponed, histologically classified as immature teratomas, having pseudodiploid karyotypes with complex structural rearrangements but lacking isochromosome 12p or other rearrangements involving 12p. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::bd2444d26fb1a9be8c5fd0cc74daa481
https://research.rug.nl/en/publications/c9b6201f-e0cc-4f49-b7d9-be6c409a9f7a

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OVERREPRESENTATION OF CHROMOSOME 12P SEQUENCES AND KARYOTYPIC EVOLUTION IN I(12P)-NEGATIVE TESTICULAR GERM-CELL TUMORS REVEALED BY FLUORESCENCE IN-SITU HYBRIDIZATION

Autor: SUIJKERBUIJK, RF, SINKE, RJ, MELONI, AM, PARRINGTON, JM, VANECHTEN, J, DEJONG, B, OOSTERHUIS, JW, SANDBERG, AA, VANKESSEL, AG

Publikováno v: Cancer Genetics and Cytogenetics, 70(2), 85-93. ELSEVIER SCIENCE INC

Human testicular germ-cell tumors (TGCTs) comprise a heterogeneous group of solid neoplasms. These tumors are characterized by the presence of a highly specific chromosomal abnormality, i.e., an isochromosome of the short arm of chromosome 12. At pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::2fc40a8ebee0afd433ac5a41d4c17609
https://research.rug.nl/en/publications/4a16a6e2-2daf-44d5-ad64-80292aff65c8

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DEMONSTRATION OF THE GENUINE ISO-12P CHARACTER OF THE STANDARD MARKER CHROMOSOME OF TESTICULAR GERM-CELL TUMORS AND IDENTIFICATION OF FURTHER CHROMOSOME-12 ABERRATIONS BY COMPETITIVE INSITU HYBRIDIZATION

Autor: SUIJKERBUIJK, RF, VANDEVEEN, AY, VANECHTEN, J, BUYS, CHCM, DEJONG, B, OOSTERHUIS, JW, WARBURTON, DA, CASSIMAN, JJ, SCHONK, D, VANKESSEL, AG

Publikováno v: American Journal of Human Genetics, 48(2), 269-273. CELL PRESS

The recently developed competitive in situ hybridization (CISH) strategy was applied to the analysis of chromosome 12 aberrations in testicular germ cell tumors (TGCTs). DNAs from two rodent-human somatic cell hybrids, containing either a normal chro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::0c85af32ab509eeb7b9571e3e4c62973
https://research.rug.nl/en/publications/a4039525-b671-4db4-add1-de2ff7974093

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Lymphomas with testicular localisation show a consistent BCL-2 expression without a translocation (14;18): a molecular and immunohistochemical study

Autor: AC LAMBRECHTS, LHJ LOOIJENGA, MB VANTVEER, Vanechten, J., Wim Timens, JW OOSTERHUIS

Publikováno v: ResearcherID
British Jounal of Cancer, 71(1), 73-77. Nature Publishing Group
Scopus-Elsevier
University of Groningen

The presence of the BCL-2 protein was studied in nine non-Hodgkin's lymphomas with testicular localisation. A consistent presence of the BCL-2 protein was found. The chromosomal translocation (14;18) was seen neither by cytogenetic analysis (n = 4) n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::470ea6f1785aa7ad81f3e4d014221ad6
https://www.ncbi.nlm.nih.gov/pubmed/7819053

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