Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Vandormael Bart"'
Autor:
Guillemyn Karel, Kleczkowska Patrycja, Novoa Alexandre, Vandormael Bart, Van den Eynde Isabelle, Kosson Piotr, Asim Muhammad, Schiller Peter W, Spetea Mariana, Lipkowski Andrzej W, Tourwé Dirk, Ballet Steven
Publikováno v:
Molecular Brain, Vol 5, Iss 1, p 4 (2012)
Abstract Background An important limiting factor in the development of centrally acting pharmaceuticals is the blood-brain barrier (BBB). Transport of therapeutic peptides through this highly protective physiological barrier remains a challenge for p
Externí odkaz:
https://doaj.org/article/9054f1e05dc644bf96469ce02a006483
Autor:
Guillemyn, Karel, Kleczkowska, Patrycja, Novoa, Alexandre, Vandormael, Bart, Van Den Eynde, Isabelle, Kosson, P., Asim, Muhammad Faheem, Schiller, P.w., Spetea, Mariana, Lipkowski, A.w., Tourwe, Dirk, Ballet, Steven
Background: An important limiting factor in the development of centrally acting pharmaceuticals is the bloodbrain barrier (BBB). Transport of therapeutic peptides through this highly protective physiological barrier remains a challenge for peptide dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3848::03b0f200b685ef2365cba7d9f656c980
https://biblio.vub.ac.be/vubir/(9e50a7fc-6e09-47e2-968e-9ec36cd4b4f3).html
https://biblio.vub.ac.be/vubir/(9e50a7fc-6e09-47e2-968e-9ec36cd4b4f3).html
Autor:
Vandormael, Bart, Fourla, Danai-Dionysia, Gramowski-Voss, Alexandra, Kosson, P., Weiss, Dieter G., Schroder, Olaf, Lipkowski, A.w., Georgoussi, Zafiroula, Tourwe, Dirk
Novel dermorphin tetrapeptides are described in which Tyr(1) is replaced by Dmt(1), where D-Ala(2) and Gly(4) are N-methylated, and where Phe(3)-Gly(4) residue is substituted by the constrained Aba(3)-Gly(4) peptidomimetic. Most of these peptidic lig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3848::1be67ba86d9eabbb220a3c7b41509fbf
https://biblio.vub.ac.be/vubir/superpotent-dmt1dermorphin-tetrapeptides-containing-the-4aminotetrahydro2benzazepin3one-scaffold-with-mixed-mudelta-opioid-receptor-agonistic-properties(f7703b46-a79b-48a1-b5e8-3ebba6ca4d83).html
https://biblio.vub.ac.be/vubir/superpotent-dmt1dermorphin-tetrapeptides-containing-the-4aminotetrahydro2benzazepin3one-scaffold-with-mixed-mudelta-opioid-receptor-agonistic-properties(f7703b46-a79b-48a1-b5e8-3ebba6ca4d83).html
Autor:
Vandormael, Bart, De Wachter, Rien, Martins, Jose C., Hendrickx, Pieter M. S., Keresztes, A., Ballet, Steven, Mallareddy, Jayapal Reddy, Toth, Fanny, Tóth, Géza, Tourwe, Dirk
Dermorphin analogues, containing a (S)- and (R)-4-amino1,2,4,5-tetrahydro-2-benzazepin-3-one scaffold (Aba) and the alpha-methylated analogues as conformationally constrained phenylalanines, were prepared. Asymmetric phase-transfer catalysis was unab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3848::c38dedf6268136f682d382e670db16dd
https://hdl.handle.net/20.500.14017/89807900-6aaa-4ccd-89dd-1781cd04563a
https://hdl.handle.net/20.500.14017/89807900-6aaa-4ccd-89dd-1781cd04563a
Autor:
De Wachter, Rien, De Graaf, Chris, Keresztes, A., Vandormael, Bart, Ballet, Steven, Tóth, Géza, Rognan, Didier, Tourwe, Dirk
The Phe(3) residue of the N-terminal tetrapeptide of dermorphin (H-Dmt-D-Ala-Phe-Gly-NH2) was conformationally constrained using 4- or 5-methyl-substituted 4-amino-1,2,4,5-tetrahydro-2-benzazepin-3-one (Aba) stereoisomeric scaffolds. Several of the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3848::fa5b60c1a58e34deef17a5d86a581186
https://biblio.vub.ac.be/vubir/(dc278902-1ea4-406e-b657-7c695eb00b7c).html
https://biblio.vub.ac.be/vubir/(dc278902-1ea4-406e-b657-7c695eb00b7c).html
Autor:
Vandormael, Bart, Tourwe, Dirk
meeting abstract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3848::f410a81d5c1937749d79ee5253fca362
https://biblio.vub.ac.be/vubir/development-of-a-new-strategy-for-the-synthesis-of-4aminotetrahydro2benzazepin3one-containing-peptides(0dc1222e-34d4-418b-948f-64e3e9a25b85).html
https://biblio.vub.ac.be/vubir/development-of-a-new-strategy-for-the-synthesis-of-4aminotetrahydro2benzazepin3one-containing-peptides(0dc1222e-34d4-418b-948f-64e3e9a25b85).html
Autor:
Vandormael, Bart, De Wachter, Rien, Martins, José C., Hendrickx, Pieter M. S., Keresztes, Attila, Ballet, Steven, Mallareddy, Jayapal R., Tóth, Fanni, Tóth, Géza, Tourwé, Dirk
Publikováno v:
ChemMedChem; Nov2011, Vol. 6 Issue 11, p2035-2047, 13p
Autor:
De Wachter, Rien, de Graaf, Chris, Keresztes, Atilla, Vandormael, Bart, Ballet, Steven, ToÌth, GeÌza, Rognan, Didier, TourweÌ, Dirk
Publikováno v:
Journal of Medicinal Chemistry; Oct2011, Vol. 54 Issue 19, p6538-6547, 10p
Autor:
Vandormael B; Department of Organic Chemistry, Vrije Universiteit Brussel, Pleinlaan 2, B-1050 Brussels, Belgium., Fourla DD, Gramowski-Voss A, Kosson P, Weiss DG, Schröder OH, Lipkowski A, Georgoussi Z, Tourwé D
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2011 Nov 24; Vol. 54 (22), pp. 7848-59. Date of Electronic Publication: 2011 Oct 20.