Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Vandestienne A"'
Autor:
Mouna Chajadine, Ludivine Laurans, Tobias Radecke, Nirmala Mouttoulingam, Rida Al-Rifai, Emilie Bacquer, Clara Delaroque, Héloïse Rytter, Marius Bredon, Camille Knosp, José Vilar, Coralie Fontaine, Nadine Suffee, Marie Vandestienne, Bruno Esposito, Julien Dairou, Jean Marie Launay, Jacques Callebert, Alain Tedgui, Hafid Ait-Oufella, Harry Sokol, Benoit Chassaing, Soraya Taleb
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Tryptophan (Trp) is an essential amino acid, whose metabolism is a key gatekeeper of intestinal homeostasis. Yet, its systemic effects, particularly on atherosclerosis, remain unknown. Here we show that high-fat diet (HFD) increases the acti
Externí odkaz:
https://doaj.org/article/23e8da68ab054d8cb1eca0785be8840f
Autor:
Yujiao Zhang, Marie Vandestienne, Jean-Rémi Lavillegrand, Jeremie Joffre, Icia Santos-Zas, Aonghus Lavelle, Xiaodan Zhong, Wilfried Le Goff, Maryse Guérin, Rida Al-Rifai, Ludivine Laurans, Patrick Bruneval, Coralie Guérin, Marc Diedisheim, Melanie Migaud, Anne Puel, Fanny Lanternier, Jean-Laurent Casanova, Clément Cochain, Alma Zernecke, Antoine-Emmanuel Saliba, Michal Mokry, Jean-Sebastien Silvestre, Alain Tedgui, Ziad Mallat, Soraya Taleb, Olivia Lenoir, Cécile Vindis, Stéphane M. Camus, Harry Sokol, Hafid Ait-Oufella
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Caspase recruitment-domain containing protein 9 (CARD9) is a key signaling pathway in macrophages but its role in atherosclerosis is still poorly understood. Global deletion of Card9 in Apoe -/- mice as well as hematopoietic deletion in Ldlr
Externí odkaz:
https://doaj.org/article/b269b498eb06438890385181c12ba8bb
Akademický článek
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Akademický článek
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Autor:
Rida Al-Rifai, Marie Vandestienne, Jean-Rémi Lavillegrand, Tristan Mirault, Julie Cornebise, Johanne Poisson, Ludivine Laurans, Bruno Esposito, Chloé James, Olivier Mansier, Pierre Hirsch, Fabrizia Favale, Rayan Braik, Camille Knosp, Jose Vilar, Giuseppe Rizzo, Alma Zernecke, Antoine-Emmanuel Saliba, Alain Tedgui, Maxime Lacroix, Lionel Arrive, Ziad Mallat, Soraya Taleb, Marc Diedisheim, Clément Cochain, Pierre-Emmanuel Rautou, Hafid Ait-Oufella
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
JAK2V617F mutation is associated with an increased risk for athero-thrombotic cardiovascular disease, but its role in aortic disease development remains unknown. Here, the authors show that JAK2V617F mutation drives vascular resident macrophages towa
Externí odkaz:
https://doaj.org/article/31496f4b830e45869494a64a4bd6994e
Autor:
Khadhraoui, Nahed, Prola, Alexandre, Vandestienne, Aymeline, Blondelle, Jordan, Guillaud, Laurent, Courtin, Guillaume, Bodak, Maxime, Prost, Bastien, Huet, Hélène, Wintrebert, Mélody, Péchoux, Christine, Solgadi, Audrey, Relaix, Frédéric, Tiret, Laurent, Pilot-Storck, Fanny
Publikováno v:
In Molecular Metabolism March 2023 69
Akademický článek
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Autor:
Marie Vandestienne, Rayan Braik, Jean-Rémi Lavillegrand, Geoffroy Hariri, Zoe Demailly, Nadine Ben Hamouda, Fabienne Tamion, Thomas Clavier, Hafid Ait-Oufella
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundCardiopulmonary bypass (CPB) during cardiac surgery leads to deleterious systemic inflammation. We hypothesized that TREM-1, a myeloid receptor shed after activation, drives systemic inflammation during CPB.MethodsProspective observational
Externí odkaz:
https://doaj.org/article/06fd94eae5314b8db2c72a0a15ba044e
Autor:
Nahed Khadhraoui, Alexandre Prola, Aymeline Vandestienne, Jordan Blondelle, Laurent Guillaud, Guillaume Courtin, Maxime Bodak, Bastien Prost, Hélène Huet, Mélody Wintrebert, Christine Péchoux, Audrey Solgadi, Frédéric Relaix, Laurent Tiret, Fanny Pilot-Storck
Publikováno v:
Molecular Metabolism, Vol 69, Iss , Pp 101677- (2023)
Objective: Mitochondria fuel most animal cells with ATP, ensuring proper energetic metabolism of organs. Early and extensive mitochondrial dysfunction often leads to severe disorders through multiorgan failure. Hacd2 gene encodes an enzyme involved i
Externí odkaz:
https://doaj.org/article/6744384a329344d9a39e57dd6832e45f
Autor:
Icia Santos-Zas, Jeremie Lemarié, Ivana Zlatanova, Marine Cachanado, Jean-Christophe Seghezzi, Hakim Benamer, Pascal Goube, Marie Vandestienne, Raphael Cohen, Maya Ezzo, Vincent Duval, Yujiao Zhang, Jin-Bo Su, Alain Bizé, Lucien Sambin, Philippe Bonnin, Maxime Branchereau, Christophe Heymes, Corinne Tanchot, José Vilar, Clement Delacroix, Jean-Sebastien Hulot, Clement Cochain, Patrick Bruneval, Nicolas Danchin, Alain Tedgui, Ziad Mallat, Tabassome Simon, Bijan Ghaleh, Jean-Sébastien Silvestre, Hafid Ait-Oufella
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Immune cells contribute to adverse remodeling following myocardial infarction. Here the authors show in mice and pigs that CD8+ lymphocytes release Granzyme B in the infarcted heart leading to cardiomyocyte death, enhanced inflammation and deteriorat
Externí odkaz:
https://doaj.org/article/d22cf22ea4844f0bb37075c442f362fe