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ORAI3 silencing alters cell proliferation and promotes mitotic catastrophe and apoptosis in pancreatic adenocarcinoma

Autor: ZIENTAL GELUS , Nathalie, Vanden Abeele, Fabien, DUBOIS, Charlotte, Kondratska, Kateryna, Kondratskyi, Artem, MORABITO, Angela, MESILMANY, Lina, Farfariello, Valerio, Toillon, Robert-Alain, Gelus, Nathalie, LAURENGE, Emilie, Lemonnier, Loic, Prevarskaya, Natalia

Publikováno v: Biochimica et Biophysica Acta-Molecular Cell Research
Biochimica et Biophysica Acta-Molecular Cell Research, Elsevier, 2021, 1868 (7), pp.119023. ⟨10.1016/j.bbamcr.2021.119023⟩
Biochimica et Biophysica Acta-Molecular Cell Research, 2021, 1868 (7), pp.119023. ⟨10.1016/j.bbamcr.2021.119023⟩

International audience; Changes in cytosolic free Ca2+ concentration play a central role in many fundamental cellular processes including muscle contraction, neurotransmission, cell proliferation, differentiation, gene transcription and cell death. M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4753983f6c2641b8187c918189bd1010
https://pubmed.ncbi.nlm.nih.gov/33798603

TRPV1 variants impair intracellular Ca2+ signaling and may confer susceptibility to malignant hyperthermia

Autor: Vanden Abeele, Fabien, Lotteau, Sabine, Ducreux, Sylvie, Dubois, charlotte, Monnier, Nicole, Amy, Hanna, Gkika, Dimitra, Romestaing, Caroline, Lucile, Noyer, Flourakis, Matthieu, Tessier, Nolwenn, Al-Mawla, Ribal, Chouabe, Christophe, Lefai, Etienne, Joël, Lunardi, Hamilton, Susan, Faure, Julien, Van Coppenolle, Fabien, Prevarskaya, Natalia

Publikováno v: Genetics in Medicine
Genetics in Medicine, Nature Publishing Group, 2019, 21, pp.441-450. ⟨10.1038/s41436-018-0066-9⟩
Genetics in Medicine, Nature Publishing Group, 2019, 21 (2), pp.441-450. ⟨10.1038/s41436-018-0066-9⟩
Genetics in Medicine, 2019, 21 (2), pp.441-450. ⟨10.1038/s41436-018-0066-9⟩

International audience; Purpose: Malignant hyperthermia (MH) is a pharmacogenetic disorder arising from uncontrolled muscle calcium release due to an abnormality in the sarcoplasmic reticulum (SR) calcium-release mechanism triggered by halogenated in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ca3aec0a73e261ee01235f351c06c708
https://hal-univ-lyon1.archives-ouvertes.fr/hal-02060779

Differential effects of thapsigargin analogues on apoptosis of prostate cancer cells.

Autor: Dubois, Charlotte^1,2, Vanden Abeele, Fabien¹, Sehgal, Pankaj^2,3, Olesen, Claus^2,3, Junker, Steffen³, Christensen, Søren B.⁴, Prevarskaya, Natalia¹, Møller, Jesper V.^2,3

Publikováno v: FEBS Journal. Nov2013, Vol. 280 Issue 21, p5430-5440. 11p.