Genomic oropharyngeal Neisseria surveillance detects MALDI-TOF MS species misidentifications and reveals a novel Neisseria cinerea clade.

Autor: de Block T; Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium., De Baetselier I; Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium., Van den Bossche D; Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium., Abdellati S; Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium., Gestels Z; Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium., Laumen JGE; Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium., Van Dijck C; Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium., Vanbaelen T; Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium., Claes N; EMAT, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium., Vandelannoote K; Bacterial Phylogenomics group, Institut Pasteur du Cambodge, Phnom Penh, Cambodia., Kenyon C; Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium., Harrison O; Nuffield Department of Population Health, Infectious Diseases Epidemiology Unit, University of Oxford, Oxford, UK., Santhini Manoharan-Basil S; Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium.

Publikováno v: Journal of medical microbiology [J Med Microbiol] 2024 Aug; Vol. 73 (8).

High performance Legionella pneumophila source attribution using genomics-based machine learning classification.

Autor: Buultjens AH; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.; Center for Pathogen Genomics, University of Melbourne, Melbourne, Victoria, Australia., Vandelannoote K; Bacterial Phylogenomics Group, Institut Pasteur du Cambodge, Phnom Penh, Cambodia., Mercoulia K; Department of Microbiology and Immunology, Microbiology Diagnostic Unit, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia., Ballard S; Department of Microbiology and Immunology, Microbiology Diagnostic Unit, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia., Sloggett C; Department of Microbiology and Immunology, Microbiology Diagnostic Unit, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia., Howden BP; Center for Pathogen Genomics, University of Melbourne, Melbourne, Victoria, Australia.; Department of Microbiology and Immunology, Microbiology Diagnostic Unit, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.; Department of Infectious Diseases, Austin Health, Heidelberg, Victoria, Australia., Seemann T; Department of Microbiology and Immunology, Microbiology Diagnostic Unit, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia., Stinear TP; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.; Center for Pathogen Genomics, University of Melbourne, Melbourne, Victoria, Australia.

Publikováno v: Applied and environmental microbiology [Appl Environ Microbiol] 2024 Mar 20; Vol. 90 (3), pp. e0129223. Date of Electronic Publication: 2024 Jan 30.

Isoniazid resistance levels of Mycobacterium tuberculosis can largely be predicted by high-confidence resistance-conferring mutations.

Autor: Lempens, P., Meehan, Conor J., Vandelannoote, K., Fissette, K., de Rijk, P., Van Deun, A., Rigouts, L., de Jong, B.C.

Yes
The majority of Mycobacterium tuberculosis isolates resistant to isoniazid harbour a mutation in katG. Since these mutations cause a wide range of minimum inhibitory concentrations (MICs), largely below the serum level reached with higher do

Externí odkaz: http://hdl.handle.net/10454/17278

Multiple Introductions and Recent Spread of the Emerging Human Pathogen Mycobacterium ulcerans across Africa

Autor: Vandelannoote, K., Meehan, Conor J., Eddyani, M., Affolabi, D., Phanzu, D.M., Eyangoh, S., Jordaens, K., Portaels, F., Mangas, K., Seemann, T., Marsollier, L., Marion, E., Chauty, A., Landier, J., Fontanet, A., Leirs, H., Stinear, T.P., de Jong, B.C.

Yes
Buruli ulcer (BU) is an insidious neglected tropical disease. Cases are reported around the world but the rural regions of West and Central Africa are most affected. How BU is transmitted and spreads has remained a mystery, even though the c

Externí odkaz: http://hdl.handle.net/10454/17302

Statistical modeling based on structured surveys of Australian native possum excreta harboring Mycobacterium ulcerans predicts Buruli ulcer occurrence in humans.

Autor: Vandelannoote K; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Australia.; Bacterial Phylogenomics Group, Institut Pasteur du Cambodge, Phnom Penh, Cambodia., Buultjens AH; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Australia., Porter JL; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Australia., Velink A; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Australia., Wallace JR; Department of Biology, Millersville University, Millersville, United States., Blasdell KR; Health and Biosecurity, Commonwealth Scientific and Industrial Research Organisation, Geelong, Australia., Dunn M; Health and Biosecurity, Commonwealth Scientific and Industrial Research Organisation, Geelong, Australia., Boyd V; Health and Biosecurity, Commonwealth Scientific and Industrial Research Organisation, Geelong, Australia., Fyfe JAM; Victorian Infectious Diseases Reference Laboratory, Doherty Institute for Infection and Immunity, Melbourne, Australia., Tay EL; Health Protection branch, Department of Health, Victoria, Australia., Johnson PDR; North Eastern Public Health Unit (NEPHU), Austin Health, Melbourne, Australia., Windecker SM; School of Ecosystem and Forest Sciences, University of Melbourne, Melbourne, Australia., Golding N; Telethon Kids Institute, Perth Children's Hospital, Nedlands, Australia.; Curtin School of Population Health, Curtin University, Bentley, Australia.; Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia., Stinear TP; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Australia.

Publikováno v: ELife [Elife] 2023 Apr 14; Vol. 12. Date of Electronic Publication: 2023 Apr 14.