Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Vandana M. Sharma"'
Publikováno v:
Journal of Cell Science. 120:748-757
The microtubule-associated protein tau interacts with the SH3 domain of non-receptor Src family protein tyrosine kinases. A potential consequence of the SH3 interaction is the upregulation of tyrosine kinase activity. Here we investigated the activat
Autor:
Rita Christopher, Taranath K. Shetty, Y. Ramamohan, Pavankumar A. Shetty, Momin M. Shareef, Savitha Kalidas, Vandana M. Sharma, Harish C. Pant, Kiran Bhaskar
Publikováno v:
Neurochemistry International. 47:225-234
Munc18-1, also referred to as p67, co-purifies with Cdk5 and has an important role in neurotransmitter release. The role of Munc18-1 for functional connectivity of the nervous system was demonstrated by gene knockout experiments in mice, wherein accu
Autor:
Kiran Bhaskar, Hanna Ksiezak-Reding, Gary W. Van Hoesen, Ramasamy Thangavel, Lana H. Do, Vandana M. Sharma, Gloria Lee, Joel M. Litersky, Athena Andreadis, Sandy M. Fang
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 24(9)
The abnormal phosphorylation of tau protein on serines and threonines is a hallmark characteristic of the neurofibrillary tangles of Alzheimer's disease (AD). The discovery that tau could be phosphorylated on tyrosine and evidence that Aβ signal tra
Autor:
Kiran Bhaskar, A. Pavan Kumar Shetty, Harish C. Pant, Mohammed Momin Shareef, Trichur R. Raju, Y. Ramamohan, Vandana M. Sharma, K. Taranath Shetty
Publikováno v:
Neurochemistry international. 44(1)
Munc18-1 (p67, nSec1, rbSec1), a neuron-specific 67 kDa protein was independently identified as a syntaxin-binding protein, and as a component that co-purifies with, and regulates the kinase activity of cyclin dependent kinase (Cdk5). Gene knockout s
Publikováno v:
Neurobiology of Aging. 25:S174