Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Vandana Kalia"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/e13267b43af945d19181c656b7d5cab8
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Robust T cell responses are crucial for effective anti-tumor responses and often dictate patient survival. However, in the context of solid tumors, both endogenous T cell responses and current adoptive T cell therapies are impeded by the immunosuppre
Externí odkaz:
https://doaj.org/article/6befbc96514b41deb5717327eeee432c
Autor:
Vandana Kalia, Surojit Sarkar
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Interleukin-2 (IL-2) regulates key aspects of CD8 T cell biology–signaling through distinct pathways IL-2 triggers critical metabolic and transcriptional changes that lead to a spectrum of physiological outcomes such as cell survival, proliferation
Externí odkaz:
https://doaj.org/article/79cc87b0390940d781d8a3f7a245e026
Autor:
David E Place, David R Williamson, Yevgeniy Yuzefpolskiy, Bhuvana Katkere, Surojit Sarkar, Vandana Kalia, Girish S Kirimanjeswara
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0190384 (2017)
Progress towards a safe and effective vaccine for the prevention of tularemia has been hindered by a lack of knowledge regarding the correlates of protective adaptive immunity and a lack of tools to generate this knowledge. CD8+ T cells are essential
Externí odkaz:
https://doaj.org/article/a7458847cf2a4c4b90ebbd711dbeeda2
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162674 (2016)
MicroRNAs constitute a major post-transcriptional mechanism for controlling protein expression, and are emerging as key regulators during T cell development and function. Recent reports of augmented CD8 T cell activation and effector differentiation,
Externí odkaz:
https://doaj.org/article/86a76029019c40ed97ea5e620ef7020d
Autor:
Smita Singhal, Kedar P. Purnapatre, Vandana Kalia, Smita Dube, Deepti Nair, Monorama Deb, Pushpa Aggarwal, Sunil Gupta, Dilip J. Upadhyay, Awdhesh Kalia, V. Samuel Raj
Publikováno v:
Emerging Infectious Diseases, Vol 13, Iss 10, Pp 1614-1616 (2007)
Decreased susceptibility of Neisseria meningitidis isolates to ciprofloxacin emerged from an outbreak in Delhi, India. Results of antimicrobial susceptibility testing of the meningococcal isolates to ciprofloxacin and further sequencing of DNA gyrase
Externí odkaz:
https://doaj.org/article/b86d544e61c4472888c10ed6d14237be
Autor:
Vandana Kalia, Jim Reed, Asheema Khanna, Ryma Toumi, Hanxi Xiao, Thomas Pulliam, Rucha Deo, Paul Nghiem, Surojit Sarkar
Stem-like progenitor exhausted CD8 T cells are critical for maintaining long-term resistance during chronic infections and cancer, and represent an important checkpoint blockade immunotherapy target for functional reinvigoration and disease control.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb337dcc1c17ddedf01d49c5271a601b
https://doi.org/10.1101/2023.05.25.541936
https://doi.org/10.1101/2023.05.25.541936
Autor:
Allison R Hanaford, Asheema Khanna, Katerina James, Yihan Chen, Michael Mulholland, Bernhard Kayser, Vivian Truong, Margaret Sedensky, Phil Morgan, Vandana Kalia, Nathan Baerchst, Surojit Sarkar, Simon C Johnson
Subacute necrotizing encephalopathy, or Leigh syndrome (LS), is the most common paediatric presentation of genetic mitochondrial disease. LS is a multi-system disorder with severe neurologic, metabolic, and musculoskeletal symptoms. The presence of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2605f8a2e68efa1e4d3edadc622be15d
https://doi.org/10.1101/2023.01.27.525842
https://doi.org/10.1101/2023.01.27.525842
Autor:
Tarani Kanta Barman, Manoj Kumar, Tridib Chaira, Smita Singhal, Tarun Mathur, Vandana Kalia, Ramkumar Gangadharan, Madhvi Rao, Manisha Pandya, Pragya Bhateja, Ruchi Sood, Dilip J. Upadhyay, Shibu Varughese, Ajay Yadav, Lalima Sharma, Naresh Kumar, Jitendra Sattigeri, Pradip K. Bhatnagar, V. Samuel Raj
Development of a novel inhibitor targeting Gyrase B and Topoisomerase IV offers a potential opportunity to combat the drug resistance. In the present study, we extensively investigated the efficacy of RBx 10080758, a novel fluorobenzothiazole, agains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5bc2363635c3362ea23e722bbc23d1b
https://doi.org/10.1101/2022.09.08.507076
https://doi.org/10.1101/2022.09.08.507076
Autor:
Adithya Vegaraju, Vandana Kalia, Candice D. Church, Yevgeniy Yuzefpolskiy, Paul Nghiem, Florian M. Baumann, Surojit Sarkar, Martin Prlic, Abhishek Jha, Hanxi Xiao, Shashank Jatav, Stanley R. Riddell
Publikováno v:
Sci Transl Med
Inhibitory signaling in dysfunctional CD8 T cells through the programmed cell death 1 (PD-1) axis is well established in chronic viral infections and cancers. PD-1 is also transiently induced to high concentrations during priming of acute infections