Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Vandana Deora"'
Autor:
Vandana Deora, Trent M. Woodruff, Richard D. Gordon, Eduardo A. Albornoz, Cyril J. Jagaraj, John D. Lee, Avril A. B. Robertson, Justin J. Yerbury, Julie D. Atkin, Kate Schroder, Mark E. Cooper, Luke McAlary
Publikováno v:
Glia. 68:407-421
Microglial NLRP3 inflammasome activation is emerging as a key contributor to neuroinflammation during neurodegeneration. Pathogenic protein aggregates such as β-amyloid and α-synuclein trigger microglial NLRP3 activation, leading to caspase-1 activ
Publikováno v:
Journal of Neuroimmune Pharmacology. 12:568-574
Parkinson's disease (PD) is recognized as the most common neurodegenerative movement disorder and results in debilitating motor deficits. The accumulation and spread of neurotoxic synuclein aggregates in the form of Lewy bodies is a key pathological
Autor:
Fabio Pereira Gomes, Peter J. Cabot, Kye Gregory, Vandana Deora, Nan Xie, Paul N. Shaw, Tharindu Vithanage, Zeyad D. Nassar, Marie-Odile Parat, David Sturgess
Publikováno v:
Brain, behavior, and immunity. 61
In this study, we quantified the ability of opioids present in biological samples to activate the μ-opioid receptor and TLR4 using cell-based assays. Each assay was standardised, in the presence of plasma, using morphine, its μ receptor-active meta
Autor:
Trent M. Woodruff, John D. Lee, Susanna Mantovani, Richard J. Clark, Richard D. Gordon, Vandana Deora, Justin J. Yerbury, Julie D. Atkin
Publikováno v:
Molecular Immunology. 89:168