Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Vandana Chinwalla"'
Autor:
Clayton W. Naeve, Karen M. Rakestraw, Martin U. Kuefer, Susana C. Raimondi, Vandana Chinwalla, Frederick G. Behm, Nancy J. Zeleznik-Le, Suraj Mukatira, Stephan W. Morris
Publikováno v:
Oncogene. 22:1418-1424
Translocations interrupting the mixed lineage leukemia gene (MLL) occur in 7–10% of acute lymphoblastic leukemia (ALL) and 5–6% of acute myeloid leukemia (AML) cases. One of these translocations, t(11;15)(q23;q14), occurs rarely in both ALL and A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c31149389033f398dc46514960d9fd8
https://doi.org/10.1038/sj.onc.1206272
https://doi.org/10.1038/sj.onc.1206272
Autor:
Janet D. Rowley, María D. Odero, Andy S. Chien, Nancy J. Zeleznik-Le, Vandana Chinwalla, Mary Beth Neilly
Publikováno v:
Oncogene. 22:1400-1410
The mixed lineage leukemia gene (MLL, also known as HRX, ALL-1 and Htrx) located at 11q23 is involved in translocations with over 40 different chromosomal bands in a variety of leukemia subtypes. Here we report our analysis of a rare but recurring tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afdefa481784b1677b2d65ffbc45ff75
https://doi.org/10.1038/sj.onc.1206273
https://doi.org/10.1038/sj.onc.1206273
Publikováno v:
Genes, Chromosomes and Cancer. 29:333-338
Cell lines derived from patients with leukemia are used in many molecular biology studies. Here we report the cytogenetic analysis of the THP-1 cell line using G-banding, fluorescence in situ hybridization (FISH), and spectral karyotyping (SKY), and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b35369e8b5145c1481ee0462a4d5c2e5
https://doi.org/10.1002/1098-2264(2000)9999:9999<::aid-gcc1040>3.0.co
https://doi.org/10.1002/1098-2264(2000)9999:9999<::aid-gcc1040>3.0.co
Publikováno v:
Mechanisms of Development. 52:89-98
We show that maintenance but not initiation of engrailed (en) gene expression in the Drosophila embryo requires trithorax (trx) , which is also required to maintain stable long-term expression of the homeotic genes throughout development. Like the ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f828e4deeedb016f10c5c06452dd7494
https://doi.org/10.1016/0925-4773(95)00393-f
https://doi.org/10.1016/0925-4773(95)00393-f
Publikováno v:
The EMBO Journal. 14:2056-2065
trithorax is required to stably maintain homeotic gene expression patterns established during embryogenesis by the action of the transiently expressed products of the segmentation genes. The large trithorax proteins contain a number of highly conserv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a2f03d6ad4a46cc4d322599d11b31c9
https://doi.org/10.1002/j.1460-2075.1995.tb07197.x
https://doi.org/10.1002/j.1460-2075.1995.tb07197.x
Publikováno v:
Transcription Factors: Normal and Malignant Development of Blood Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3940cdaf111471267433d23e9d0026dd
https://doi.org/10.1002/0471223883.ch26
https://doi.org/10.1002/0471223883.ch26
Autor:
María José Calasanz, Katrin M. Carlson, Idoya Lahortiga, Janet D. Rowley, Vandana Chinwalla, María D. Odero
Publikováno v:
Genes, chromosomescancer. 31(2)
TEL/ETV6 is the first transcription factor identified that is specifically required for hematopoiesis within the bone marrow. This gene has been found to have multiple fusion partners; 35 different chromosome bands have been involved in ETV6 transloc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::178050b73c0ac9d3fab16becea7214b8
https://pubmed.ncbi.nlm.nih.gov/11319801
https://pubmed.ncbi.nlm.nih.gov/11319801
In Drosophila, the maintenance of developmentally important transcription patterns is controlled at the level of chromatin structure. The Polycomb group (PcG) and trithorax group (trxG) genes encode proteins involved in chromatin remodelling. PcG gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04182417240253ae8bad7f0fd3a8c0c6
https://europepmc.org/articles/PMC1170842/
https://europepmc.org/articles/PMC1170842/
Publikováno v:
Mechanisms of development. 52(2-3)
The products of the trithorax gene are required to stably maintain homeotic gene expression patterns established during embryogenesis by the action of the transiently expressed segmentation genes. We have determined the intron/exon structure of the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bfdf1a2f03409c2efe566c2c51d8f46
https://pubmed.ncbi.nlm.nih.gov/8541210
https://pubmed.ncbi.nlm.nih.gov/8541210