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pro vyhledávání: '"Vandana B. Sharma"'
Supplementary Figure Legend from Defective Repair of Oxidative DNA Damage in Triple-Negative Breast Cancer Confers Sensitivity to Inhibition of Poly(ADP-Ribose) Polymerase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825796f8e8887667911592147ed54e97
https://doi.org/10.1158/0008-5472.22379531.v1
https://doi.org/10.1158/0008-5472.22379531.v1
Subtypes of breast cancer that represent the two major types of epithelial cells in the breast (luminal and basal) carry distinct histopathologic profiles. Breast cancers of the basal-like subtype, which include the majority of hereditary breast canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceba044c816f3ab65ed125bdc5ddd451
https://doi.org/10.1158/0008-5472.c.6499271.v1
https://doi.org/10.1158/0008-5472.c.6499271.v1
Supplementary Figure 1 from Defective Repair of Oxidative DNA Damage in Triple-Negative Breast Cancer Confers Sensitivity to Inhibition of Poly(ADP-Ribose) Polymerase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71ed45364d3a4ca413f62a8b5b42c367
https://doi.org/10.1158/0008-5472.22379534
https://doi.org/10.1158/0008-5472.22379534
Autor:
Erich J. Schwartz, Elizabeth A. Schackmann, Adrian M. Fernandez, Elizabeth Alli, Allison W. Kurian, Ani Kardashian, Meredith A. Mills, Ashley D. Staton, James M. Ford, Vandana B. Sharma, Shaveta Vinayak, Melinda L. Telli, Lisa A. McPherson, Jafi A. Lipson, Kristin C. Jensen
Pre-clinical and epidemiologic studies provide rationale for evaluating lipophilic statins for breast cancer prevention. We conducted a single-arm, biomarker modulation trial of lovastatin among women with increased risk of breast cancer. Eligibility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9917ed5bc5dec49b3bb243bd31122546
https://europepmc.org/articles/PMC5508753/
https://europepmc.org/articles/PMC5508753/
Enhanced sensitivity to cisplatin and gemcitabine in Brca1-deficient murine mammary epithelial cells
Autor:
Patrick S. Lin, Elizabeth Alli, Lisa A. McPherson, James M. Ford, Vandana B. Sharma, Anne-Renee Hartman
Publikováno v:
BMC Pharmacology
Background Breast cancers due to germline mutations or altered expression of the BRCA1 gene associate with an aggressive clinical course and frequently exhibit a "triple-negative" phenotype, i.e. lack of expression of the estrogen and progesterone ho
Publikováno v:
Cancer research. 69(8)
Subtypes of breast cancer that represent the two major types of epithelial cells in the breast (luminal and basal) carry distinct histopathologic profiles. Breast cancers of the basal-like subtype, which include the majority of hereditary breast canc
Autor:
German Gil, Raphaël Métivier, Kendall W. Nettles, Geoffrey L. Greene, Jason Nowak, Vandana B. Sharma
Publikováno v:
Molecular Endocrinology-Baltimore
Molecular Endocrinology-Baltimore-, Endocrine Society, 2008, 22 (2), pp.263-272. ⟨10.1210/me.2007-0324⟩
Molecular Endocrinology-Baltimore-, 2008, 22 (2), pp.263-272. ⟨10.1210/me.2007-0324⟩
Molecular Endocrinology-Baltimore-, Endocrine Society, 2008, 22 (2), pp.263-272. ⟨10.1210/me.2007-0324⟩
Molecular Endocrinology-Baltimore-, 2008, 22 (2), pp.263-272. ⟨10.1210/me.2007-0324⟩
International audience; The estrogen receptor (ER) protects against debilitating effects of the inflammatory response by inhibiting the proinflammatory transcription factor nuclear factor-kappaB (NFkappaB). Heretofore cAMP response element-binding pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca97c2462961105434047bd32bad0848
https://europepmc.org/articles/PMC2234588/
https://europepmc.org/articles/PMC2234588/
Publikováno v:
Journal of Clinical Oncology. 25:10606-10606
10606 Introduction: The BRCA1 tumor suppressor protein has been implicated in many cellular processes, including several different DNA repair pathways. Inherited mutations in the BRCA1 gene result in an increased risk for developing breast and ovaria