Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Vandana, Singhal"'
Autor:
Theresa A. Shapiro, Gary H. Posner, Nirbhay Kumar, Bryan T. Mott, Vandana Singhal, Lauren E. Woodard
Publikováno v:
Pharmaceuticals, Vol 2, Iss 3, Pp 228-235 (2009)
Three thermally and hydrolytically stable silylamide trioxanes have been prepared from the natural trioxane artemisinin in only five simple chemical steps and in at least 56% overall yield. Two of these new chemical entities completely cured malariai
Externí odkaz:
https://doaj.org/article/73d88e2847ad49beab26f7b93ff74b1b
Autor:
Ryan E. Tomlinson, Marie Claude Faugere, Angelica J. Herrera, Brian C. Goh, Vandana Singhal, Se-Jin Lee, Douglas J. DiGirolamo, Thomas L. Clemens, Emily L. Germain-Lee, Soo-Hyun Kim
Publikováno v:
Journal of Biological Chemistry. 292:13809-13822
Bone and skeletal muscle mass are highly correlated in mammals, suggesting the existence of common anabolic signaling networks that coordinate the development of these two anatomically adjacent tissues. The activin signaling pathway is an attractive
Autor:
William A. Gahl, John D. Heiss, Vandana Singhal, Joseph A. Shrader, Angela Gruber, John Perreault, Prashant Chittiboina, Christina Slota, Aaron Poliak, Christina Hayes, Carla Ciccone, Marjan Huizing, May Christine V. Malicdan, Jennifer Garland, Joshi Stephen, Bradley Class, Ralitza H. Gavrilova, Galen O. Joe, Nuria Carrillo
Publikováno v:
Molecular Genetics & Genomic Medicine. 5:410-417
Background GNE myopathy is a rare genetic disease characterized by progressive muscle atrophy and weakness. It is caused by biallelic mutations in the GNE gene that encodes for the bifunctional enzyme, uridine diphosphate (UDP)-N-acetylglucosamine (G
Autor:
Jennifer, Garland, Joshi, Stephen, Bradley, Class, Angela, Gruber, Carla, Ciccone, Aaron, Poliak, Christina P, Hayes, Vandana, Singhal, Christina, Slota, John, Perreault, Ralitza, Gavrilova, Joseph A, Shrader, Prashant, Chittiboina, Galen, Joe, John, Heiss, William A, Gahl, Marjan, Huizing, Nuria, Carrillo, May Christine V, Malicdan
Publikováno v:
Molecular Genetics & Genomic Medicine
Background GNE myopathy is a rare genetic disease characterized by progressive muscle atrophy and weakness. It is caused by biallelic mutations in the GNE gene that encodes for the bifunctional enzyme, uridine diphosphate (UDP)‐N‐acetylglucosamin
Autor:
Lauren E. Woodard, Gary H. Posner, Bryan T. Mott, Nirbhay Kumar, Vandana Singhal, Theresa A. Shapiro
Publikováno v:
Pharmaceuticals, Vol 2, Iss 3, Pp 228-235 (2009)
Pharmaceuticals; Volume 2; Issue 3; Pages: 228-235
Pharmaceuticals
Pharmaceuticals; Volume 2; Issue 3; Pages: 228-235
Pharmaceuticals
Three thermally and hydrolytically stable silylamide trioxanes have been prepared from the natural trioxane artemisinin in only five simple chemical steps and in at least 56% overall yield. Two of these new chemical entities completely cured malaria-
Publikováno v:
Bone Research
A large body of literature suggests that bone metabolism is susceptible to the ill effects of reactive species that accumulate in the body and cause cellular dysfunction. One of the body's front lines in defense against such damage is the transcripti
Growth hormone (GH) exerts profound anabolic actions during postnatal skeletal development, in part, through stimulating the production of insulin-like growth factor-1 (IGF-1) in liver and skeletal tissues. To examine the requirement for the GH recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f9573df9c1377becb2e42a3e382f57
https://europepmc.org/articles/PMC4472095/
https://europepmc.org/articles/PMC4472095/
Autor:
Anju Singh, Meixia Gao, Ernst W. Spannhake, Shyam Biswal, Kristin Macri, Vandana Singhal, Curt Reynolds
Publikováno v:
Respiratory Research, Vol 12, Iss 1, p 92 (2011)
Respiratory Research
Respiratory Research
Background The upper respiratory tract functions to protect lower respiratory structures from chemical and biological agents in inspired air. Cellular oxidative stress leading to acute and chronic inflammation contributes to the resultant pathology i
Three new 5-carbon-linked trioxane dimer carboxylate esters have been prepared from the natural trioxane, artemisinin in only 3-steps and 40-50% overall yields. Each one of these new chemical entities is at least as efficacious as the clinically used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05f314a57b059e5a78c5a2df1a5e183b
https://europepmc.org/articles/PMC2913489/
https://europepmc.org/articles/PMC2913489/
Autor:
Amit Sharma, Balaram Ghosh, Vandana Singhal, Reema Roshan, Gopal Waman Rembhotkar, Sarvesh Kumar
Publikováno v:
European journal of pharmacology. 575(1-3)
Piperine displays antipyretic, analgesic, insecticidal and anti-inflammatory activities. It is the first amide to be isolated from Piper species. In the process of identifying non-steroidal anti-inflammatory small molecules from the natural sources,