Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Vanda Lucia Dos Santos"'
1
Akademický článek
The Development and Pre-Clinical Anti-Inflammatory Efficacy of a New Transdermal Ureasil–Polyether Hybrid Matrix Loaded with Flavonoid-Rich Annona muricata Leaf Extract
Autor: Camila Beatriz Barros Araújo, José de Oliveira Alves Júnior, Mariana Rillo Sato, Kammila Martins Nicolau Costa, Jéssica Roberta Lima, Bolívar Ponciano Goulart de Lima Damasceno, Francisco José Batista de Lima Junior, Bruna Galdorfini Chiari Andréo, Vanda Lucia dos Santos, João Augusto Oshiro-Junior
Publikováno v: Pharmaceutics, Vol 16, Iss 8, p 1097 (2024)
This study aimed to develop a novel ureasil–polyether transdermal hybrid matrix (U-PEO) loaded with Annona muricata concentrated extract (AMCE), which exhibits potent anti-inflammatory activity. The extract was obtained by maceration, a method that
Externí odkaz: https://doaj.org/article/25e764aa639045eebe7ebba02002015e
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2
Akademický článek
Anti-Inflammatory Activity of N′-(3-(1H-indol-3-yl)benzylidene)-2-cyanoacetohydrazide Derivative via sGC-NO/Cytokine Pathway
Autor: Pablo Rayff da Silva, Nadjaele de Melo Apolinário, Simone Ângela Soares da Silva, Maria Elaine Cristina Araruna, Thássia Borges Costa, Yvnni M. S. de Medeiros e Silva, Teresinha Gonçalves da Silva, Ricardo Olímpio de Moura, Vanda Lucia dos Santos
Publikováno v: Pharmaceuticals, Vol 16, Iss 10, p 1415 (2023)
The N-acylhydrazone function has been reported as a pharmacophore group of molecules with diverse pharmacological activities, including anti-inflammatory effects. Therefore, this study was designed to evaluate the anti-inflammatory potential of the c
Externí odkaz: https://doaj.org/article/6b05fe073dbc46118837537e5ecd7711
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3
Akademický článek
The Compound (E)-2-Cyano-N,3-diphenylacrylamide (JMPR-01): A Potential Drug for Treatment of Inflammatory Diseases
Autor: Pablo Rayff da Silva, Renan Fernandes do Espírito Santo, Camila de Oliveira Melo, Fábio Emanuel Pachú Cavalcante, Thássia Borges Costa, Yasmim Vilarim Barbosa, Yvnni M. S. de Medeiros e Silva, Natália Ferreira de Sousa, Cristiane Flora Villarreal, Ricardo Olímpio de Moura, Vanda Lucia dos Santos
Publikováno v: Pharmaceutics, Vol 14, Iss 1, p 188 (2022)
The compound (E)-2-cyano-N,3-diphenylacrylamide (JMPR-01) was structurally developed using bioisosteric modifications of a hybrid prototype as formed from fragments of indomethacin and paracetamol. Initially, in vitro assays were performed to determi
Externí odkaz: https://doaj.org/article/85db4375e4404b08839ab18499a6d0a8
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4
Bioguided Isolation of Alkaloids and Pharmacological Effects of the Total Alkaloid Fraction from Aspidosperma pyrifolium Mart. (Apocynaceae)
Autor: Vanessa Farias da Silva, Josean Fechine Tavares, Francisca Sabrina Vieira Lins, Harley da Silva Alves, Vanda Lucia Dos Santos
Publikováno v: Plants
Plants, Vol 10, Iss 2526, p 2526 (2021)
Volume 10
Issue 11
Aspidosperma pyrifolium is used in traditional medicine to treat inflammatory disorders. The aim of the study was to perform phytochemical characterization and evaluate the anti-inflammatory, anti-nociceptive and acute toxicity effects of the total a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae35dd510cf1eac9561afd1099833701
http://europepmc.org/articles/PMC8625095
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5
Tablet of Spondias mombin L. Developed from Nebulized Extract Prevents Gastric Ulcers in Mice via Cytoprotective and Antisecretory Effects
Autor: Ana Cláudia Dantas de Medeiros, Vanda Lucia Dos Santos, Raiff Dantas, Maria do Socorro Oliveira de Almeida, Francinalva Dantas de Medeiros, Hilton Albuquerque, Pablo Rayff Da Silva, Nadjaele Apolinário, Maria Elaine Cristina Araruna, Ingrid Cabral, Renaly Ivyna de Araújo Rêgo
Publikováno v: Molecules
Volume 26
Issue 6
Molecules, Vol 26, Iss 1581, p 1581 (2021)
Spondias mombin L. (Anacardiaceae) has a worldwide distribution and is present in all regions of Brazil. Its leaves, flowers and bark are used as teas in folk medicine to treat diseases of the digestive system. This study aimed to evaluate the acute
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b24b6086a42da17fc598cb33e101c77e
http://europepmc.org/articles/PMC8001497
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6
(E)-2-Cyano-3-(1H-Indol-3-yl)-N-Phenylacrylamide, a Hybrid Compound Derived from Indomethacin and Paracetamol: Design, Synthesis and Evaluation of the Anti-Inflammatory Potential
Autor: Maria do Socorro Oliveira de Almeida, Maria Lima, Jamire Muriel Da Silva, Pablo Rayff Da Silva, Cristiane Flora Villarreal, Vanda Lucia Dos Santos, Sonaly Lima Albino, Renan Fernandes do Espírito-Santo, Ricardo Olímpio de Moura
Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 2591, p 2591 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 7
The compound (E)-2-cyano-3-(1H-indol-3-yl)-N-phenylacrylamide (ICMD-01) was designed and developed based on the structures of clinically relevant drugs indomethacin and paracetamol through the molecular hybridization strategy. This derivative was obt
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35982e46ef15788f45bca46f7f692dc9
https://www.mdpi.com/1422-0067/21/7/2591
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8
Spondias purpureaL. (Anacardiaceae): Antioxidant and Antiulcer Activities of the Leaf Hexane Extract
Autor: Teresinha Gonçalves da Silva, Almir Gonçalves Wanderley, Vanda Lucia Dos Santos, Samara Alves Brito, Márcia Vanusa da Silva, Larissa Araújo Rolim, Temístocles Italo de Santana, Carlson Helder Reis de Carvalho Júnior, Cynthia Layse Ferreira de Almeida, Lécio Leone de Almeida, Henrique Bandeira Alves Costa
Publikováno v: Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2017 (2017)
Spondias purpureais used in folk medicine to treat diarrhea and diuresis. The objective of this study was to evaluate the phytochemical profile and antioxidant and antiulcer activities of the hexane extract of the leaves ofS. purpurea(SpHE). Phytoche
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::356ca9c3e15536d98dc8060fc6fb3101
https://doi.org/10.1155/2017/6593073
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9
Evaluation of the Interaction between the Poincianella pyramidalis (Tul.) LP Queiroz Extract and Antimicrobials Using Biological and Analytical Models
Autor: Delcio de Castro Felismino, Cleildo P. Santana, Jocimar Silva Santos, Thiago Pereira Chaves, Felipe Hugo Alencar Fernandes, Henrique Douglas Melo Coutinho, Francinalva Dantas de Medeiros, Ana Cláudia Dantas de Medeiros, Raïssa Mayer Ramalho Catão, Vanda Lucia Dos Santos
Publikováno v: PLoS ONE, Vol 11, Iss 5, p e0155532 (2016)
Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
PLoS ONE
Made available in DSpace on 2018-11-26T15:29:37Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-05-18 State University of Paraiba, Brazil Poincianella pyramidalis (Tul.) LP Queiroz (Fabaceae) is an endemic tree of northeastern Brazil, occurrin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50272079c9e4edaf505d35655fdf8817
http://europepmc.org/articles/PMC4871567?pdf=render
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10
Study Bioprospecting of Medicinal Plant Extracts of the Semiarid Northeast: Contribution to the Control of Oral Microorganisms
Autor: Thiago Pereira Chaves, Deysiane Oliveira Brandão, Maria Suênia Pereira da Silva, Edja Maria Melo de Brito Costa, Ana Cláudia Dantas de Medeiros, Vanda Lucia Dos Santos, Amaro Lafayette Nobre Formiga Filho
Publikováno v: Evidence-Based Complementary and Alternative Medicine, Vol 2012 (2012)
Evidence-based Complementary and Alternative Medicine : eCAM
Dental pathologies can be caused by plaque-forming bacteria and yeast, which reside in the oral cavity. The bacteria growing in dental plaque, a naturally occurring biofilm, display increased resistance to antimicrobial agents. The objective was the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8248e36b077ddefaf17046ac428ec2b9
https://doi.org/10.1155/2012/681207
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