Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Vance L Mack"'
Autor:
Paul Y Kim, Audrey Y Kim, Jamie J Newman, Eleonora Cella, Thomas C Bishop, Peter J Huwe, Olga N Uchakina, Robert J McKallip, Vance L Mack, Marnie P Hill, Ifedayo Victor Ogungbe, Olawale Adeyinka, Samuel Jones, Gregory Ware, Jennifer Carroll, Jarrod F Sawyer, Kenneth H Densmore, Michael Foster, Lescia Valmond, John Thomas, Taj Azarian, Krista Queen, Jeremy P Kamil
Publikováno v:
PLOS Global Public Health, Vol 3, Iss 7, p e0001935 (2023)
The lack of routine viral genomic surveillance delayed the initial detection of SARS-CoV-2, allowing the virus to spread unfettered at the outset of the U.S. epidemic. Over subsequent months, poor surveillance enabled variants to emerge unnoticed. Ag
Externí odkaz:
https://doaj.org/article/cfc3ae84ac184d048187f70809359a05
Autor:
Paul Y. Kim, Audrey Y. Kim, Jamie J. Newman, Eleonora Cella, Thomas C. Bishop, Peter J. Huwe, Olga N. Uchakina, Robert J. McKallip, Vance L. Mack, Marnie P. Hill, Ifedayo Victor Ogungbe, Olawale Adeyinka, Samuel Jones, Gregory Ware, Jennifer Carroll, Jarrod F. Sawyer, Kenneth H. Densmore, Michael Foster, Lescia Valmond, John Thomas, Taj Azarian, Krista Queen, Jeremy P. Kamil
The lack of routine viral genomic surveillance delayed the initial detection of SARS-CoV-2, allowing the virus to spread unfettered at the outset of the U.S. epidemic. Over subsequent months, poor surveillance enabled variants to emerge unnoticed. Ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff4a6723f6817aabde5104a0407765fe
https://doi.org/10.1101/2022.10.19.512816
https://doi.org/10.1101/2022.10.19.512816
Autor:
Matthew E Halbert, Jenny H. Pham, Kevin M. Bucholtz, Catherine M. Will, Vance L. Mack, James L. Thomas, Edward Alexander Conner
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 174
3β-Hydroxysteroid dehydrogenase type 1 (3β-HSD1) is selectively expressed in human placenta, mammary glands and breast tumors in women. Human 3β-HSD2 is selectively expressed in adrenal glands and ovaries. Based on AutoDock 3 and 4 results, we hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1f66c68c92268133a97ce20d2f6b00a
https://pubmed.ncbi.nlm.nih.gov/29031687
https://pubmed.ncbi.nlm.nih.gov/29031687
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 120:192-199
In postmenopausal women, human 3beta-hydroxysteroid dehydrogenase type 1 (3beta-HSD1) is a critical enzyme in the conversion of DHEA to estradiol in breast tumors, while 3beta-HSD2 participates in the production of cortisol and aldosterone in the hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3ce5e5083ef0784e6f232f9d216691
https://doi.org/10.1016/j.jsbmb.2010.04.015
https://doi.org/10.1016/j.jsbmb.2010.04.015
Autor:
Ryan C. Stoner, James L. Thomas, Robert Huether, Vance L. Mack, Launa A. Scaccia, William L. Duax
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 107:80-87
The human type 1 (placenta, breast tumors) and type 2 (gonads, adrenals) isoforms of 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD) are key enzymes in steroidogenic pathways leading to the production of all active steroid hormones. Kinetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f089833061b1f4bdd6544309cea6c4c
https://doi.org/10.1016/j.jsbmb.2007.02.003
https://doi.org/10.1016/j.jsbmb.2007.02.003
Autor:
Geneva A. DeMars, Vance L. Mack, Maheshinie Rajapaksha, James L. Thomas, Himangshu S. Bose, Joseph A. Majzoub
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 352(1)
In human adrenarche during childhood, the secretion of dehydroepiandrosterone (DHEA) from the adrenal gland increases due to its increased synthesis and/or decreased metabolism. DHEA is synthesized by 17α-hydroxylase/17,20-lyase, and is metabolized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bce9005cc3ae90ff83820ffee5e4835
https://pubmed.ncbi.nlm.nih.gov/25355646
https://pubmed.ncbi.nlm.nih.gov/25355646
Publikováno v:
Molecular and cellular endocrinology. 301(1-2)
Human 3beta-hydroxysteroid dehydrogenase/isomerase type 1 (3beta-HSD1) is a critical enzyme in the conversion of DHEA to estradiol in breast tumors and may be a target enzyme for inhibition in the treatment of breast cancer in postmenopausal women. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::879dda99466419091c6705b773ff6626
https://pubmed.ncbi.nlm.nih.gov/18955108
https://pubmed.ncbi.nlm.nih.gov/18955108
Autor:
James L. Thomas, Kevin M. Bucholtz, J. Ross Terrell, Delaram Moshkelani, Jason A. Glow, Vance L. Mack
The human type 1 (placenta, breast tumors) and type 2 (gonads, adrenals) isoforms of 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD) are key enzymes in biosynthesis of all active steroid hormones. Human 3beta-HSD1 is a critical enzyme in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8ec8907b8b615cc985e979ff43fc77f
https://europepmc.org/articles/PMC2580795/
https://europepmc.org/articles/PMC2580795/