Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Vance Handley"'
Autor:
Erin C Jacobs, Samuel D Reyes, Celia W Campagnoni, M Irene Givogri, Kathy Kampf, Vance Handley, Vilma Spreuer, Robin Fisher, Wendy Macklin, Anthony T Campagnoni
Publikováno v:
ASN Neuro, Vol 1 (2009)
Recently, several in vitro studies have shown that the golli-myelin basic proteins regulate Ca 2+ homoeostasis in OPCs (oligodendrocyte precursor cells) and immature OLs (oligodendrocytes), and that a number of the functions of these cells are affect
Externí odkaz:
https://doaj.org/article/6efd1e870c4846948c35393335f5fe77
Autor:
Pablo M Paez, Daniel J Fulton, Vilma Spreuer, Vance Handley, Celia W Campagnoni, Anthony T Campagnoni
Publikováno v:
ASN Neuro, Vol 1 (2009)
OPCs (oligodendrocyte precursor cells) express golli proteins which, through regulation of Ca 2+ influx, appear to be important in OPC process extension/retraction and migration. The aim of the present study was to examine further the role of golli i
Externí odkaz:
https://doaj.org/article/a45df08d017f434a81ff7447389a35b2
Autor:
Anthony T. Campagnoni, D.A. Santiago González, Veronica T. Cheli, Pablo M. Paez, Vance Handley, Vilma Spreuer
Publikováno v:
Molecular Neurobiology. 53:5749-5771
The golli proteins, products of the myelin basic protein gene, are widely expressed in oligodendrocyte progenitor cells and neurons during the postnatal development of the brain. While golli appears to be important for oligodendrocyte migration and d
Autor:
Pablo M. Paez, Vance Handley, Diara A. Santiago González, Geoffrey G. Murphy, Veronica T. Cheli, Tenzing N. Lama, Vilma Spreuer
To determine whether L-type voltage-operated Ca2+channels (L-VOCCs) are required for oligodendrocyte progenitor cell (OPC) development, we generated an inducible conditional knock-out mouse in which the L-VOCC isoform Cav1.2 was postnatally deleted i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e074581507b57dc3e703e2596086cd5
https://europepmc.org/articles/PMC5083013/
https://europepmc.org/articles/PMC5083013/
Publikováno v:
The Journal of Neuroscience. 30:6422-6433
It is becoming increasingly clear that voltage-operated Ca2+channels (VOCCs) play a fundamental role in the development of oligodendrocyte progenitor cells (OPCs). Because direct phosphorylation by different kinases is one of the most important mecha
Autor:
Anthony T. Campagnoni, Vance Handley, Robin S. Fisher, Daniel Fulton, Christopher S. Colwell, Pablo M. Paez
Publikováno v:
Glia. 58:1292-1303
The golli myelin basic proteins are expressed in oligodendroglial precursor cells (OPCs) where they play a role in regulating Ca2+ homeostasis. During depolarization, they influence process outgrowth and migration through their action on voltage-oper
Publikováno v:
Journal of Neurochemistry. 62:1254-1259
The myelin basic protein (MBP) gene expresses several alternatively spliced products with the same 5' and 3' untranslated regions (UTRs). It has been reported that its expression may be regulated not only at the transcriptional level but also at the
Autor:
Ji-Ming Feng, Celia W. Campagnoni, Pablo M. Paez, Anthony T. Campagnoni, Vance Handley, Vilma Spreuer
Publikováno v:
The Journal of Neuroscience. 27:12690-12699
The myelin basic protein (MBP) gene encodes two families of proteins: the classic MBP constituents of myelin and the golli-MBPs, the function of which is less well understood. Previous work suggests that golli proteins may play a role in Ca2+homeosta
Autor:
Anthony T. Campagnoni, Vilma Spreur, Celia W. Campagnoni, Robin S. Fisher, Yuanyun Xie, Samuel D. Reyes, Vikram Kalra, Erin C. Jacobs, Yan Hong-Hu, Vance Handley, Kathy Kampf
Publikováno v:
European Journal of Neuroscience. 25:17-30
The first postmitotic neurons in the developing neocortex establish the preplate layer. These early-born neurons have a significant influence on the circuitry of the developing cortex. However, the exact timing and trajectory of their projections, be
Region-Specific Myelin Pathology in Mice Lacking the Golli Products of the Myelin Basic Protein Gene
Autor:
Timothy D. Hiltner, Ji-Ming Feng, Erin C. Jacobs, Melanie Martin, Albee Messing, Celia W. Campagnoni, T M Pribyl, Robin S. Fisher, Russell E. Jacobs, Kathy Kampf, Vance Handley, Samuel D. Reyes, Carol Readhead, Christopher S. Colwell, Anthony T. Campagnoni, Vilma Spreur
Publikováno v:
The Journal of Neuroscience. 25:7004-7013
The myelin basic protein (MBP) gene encodes two families of proteins, the classic MBP constituents of myelin and the golli-MBPs, the function of which is less well understood. In this study, targeted ablation of the golli-MBPs, but not the classic MB