Card9/neutrophil signalling axis promotes IL-17A-mediated ankylosing spondylitis.

Autor: Rosenzweig HL; Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, Oregon, USA.; Portland VA Medical Center, Portland, Oregon, USA., Vance EE; Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, Oregon, USA.; Portland VA Medical Center, Portland, Oregon, USA., Asare-Konadu K; Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, Oregon, USA., Koney KV; Portland VA Medical Center, Portland, Oregon, USA., Lee EJ; Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, Oregon, USA.; Portland VA Medical Center, Portland, Oregon, USA., Deodhar AA; Div Arthritis/Rheumatic Diseases, Oregon Health & Science University, Portland, Oregon, USA., Sen R; University of Colorado, Denver, Colorado, USA.; VA Eastern Colorado Health Care System, Aurora, Colorado, USA., Caplan L; VA Eastern Colorado Health Care System, Aurora, Colorado, USA.; Rheumatology Division, University of Colorado, Denver, Colorado, USA., Napier RJ; Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, Oregon, USA napier@ohsu.edu.; Portland VA Medical Center, Portland, Oregon, USA.; Div Arthritis/Rheumatic Diseases, Oregon Health & Science University, Portland, Oregon, USA.

Publikováno v: Annals of the rheumatic diseases [Ann Rheum Dis] 2024 Jan 11; Vol. 83 (2), pp. 214-222. Date of Electronic Publication: 2024 Jan 11.

T cell-intrinsic role for Nod2 in protection against Th17-mediated uveitis.

Autor: Napier RJ; VA Portland Health Care System, Portland, OR, 97239, USA.; Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR, 97239, USA., Lee EJ; VA Portland Health Care System, Portland, OR, 97239, USA.; Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR, 97239, USA., Davey MP; VA Portland Health Care System, Portland, OR, 97239, USA.; Department of Medicine, Oregon Health and Science University, Portland, OR, 97239, USA., Vance EE; VA Portland Health Care System, Portland, OR, 97239, USA.; Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR, 97239, USA., Furtado JM; Division of Ophthalmology, Ribeirão Preto Medical School, University of São Paulo, Butanta, Ribeirão Preto, Brazil., Snow PE; Department of Public Health, Oregon Health and Science University, Portland, OR, 97239, USA., Samson KA; Providence Cancer Institute, Portland, OR, 97213, USA., Lashley SJ; VA Portland Health Care System, Portland, OR, 97239, USA.; Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR, 97239, USA., Brown BR; Providence Medical Group, Portland, OR, 97213, USA., Horai R; Laboratory of Immunology, NEI, NIH, Bethesda, MD, 20814, USA., Mattapallil MJ; Laboratory of Immunology, NEI, NIH, Bethesda, MD, 20814, USA., Xu B; Laboratory of Immunology, NEI, NIH, Bethesda, MD, 20814, USA., Callegan MC; Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma, OK, 73104, USA.; Dean A. McGee Institute, Oklahoma City, OK, 73104, USA., Uebelhoer LS; Department of Pediatrics, Oregon Health and Science University, Portland, OR, 97239, USA., Lancioni CL; Department of Pediatrics, Oregon Health and Science University, Portland, OR, 97239, USA., Vehe RK; Department of Pediatrics, University of Minnesota and the University of Minnesota Masonic Children's Hospital, Minneapolis, MN, 55455, USA., Binstadt BA; Department of Pediatrics, University of Minnesota and the University of Minnesota Masonic Children's Hospital, Minneapolis, MN, 55455, USA.; Center for Immunology and Department of Pediatrics, University of Minnesota, Minneapolis, MN, 55455, USA., Smith JR; College of Medicine and Public Health, Flinders University, Adelaide, SA, 5042, Australia., Caspi RR; Laboratory of Immunology, NEI, NIH, Bethesda, MD, 20814, USA., Rosenzweig HL; VA Portland Health Care System, Portland, OR, 97239, USA. rosenzwh@ohsu.edu.; Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR, 97239, USA. rosenzwh@ohsu.edu.

Publikováno v: Nature communications [Nat Commun] 2020 Oct 26; Vol. 11 (1), pp. 5406. Date of Electronic Publication: 2020 Oct 26.

Fungal-derived cues promote ocular autoimmunity through a Dectin-2/Card9-mediated mechanism.

Autor: Brown BR; VA Portland Health Care System, Portland, OR, USA.; School of Medicine, Oregon Health and Science University, Portland, OR, USA., Lee EJ; VA Portland Health Care System, Portland, OR, USA.; Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR, USA., Snow PE; VA Portland Health Care System, Portland, OR, USA., Vance EE; VA Portland Health Care System, Portland, OR, USA.; Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR, USA., Iwakura Y; Research Institute for Biomedical Sciences, Tokyo University of Science, Tokyo, Japan., Ohno N; Tokyo University of Pharmacy and Life Science, Tokyo, Japan., Miura N; Tokyo University of Pharmacy and Life Science, Tokyo, Japan., Lin X; Department of Molecular and Cellular Oncology, University of Texas, MD Anderson Cancer Center, Houston, TX, USA., Brown GD; Aberdeen Fungal Group, MRC Centre for Medical Mycology, Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK., Wells CA; The University of Melbourne Centre for Stem Cell Systems, University of Melbourne, Parkville, Victoria, Australia., Smith JR; Eye and Vision Health, Flinders University School of Medicine, Adelaide, Australia., Caspi RR; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD, USA., Rosenzweig HL; VA Portland Health Care System, Portland, OR, USA.; Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR, USA.

Publikováno v: Clinical and experimental immunology [Clin Exp Immunol] 2017 Dec; Vol. 190 (3), pp. 293-303. Date of Electronic Publication: 2017 Aug 30.

Mincle Activation and the Syk/Card9 Signaling Axis Are Central to the Development of Autoimmune Disease of the Eye.

Autor: Lee EJ; VA Portland Health Care System, Portland, OR 97239; Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR 97239;, Brown BR; VA Portland Health Care System, Portland, OR 97239;, Vance EE; VA Portland Health Care System, Portland, OR 97239; Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR 97239;, Snow PE; VA Portland Health Care System, Portland, OR 97239;, Silver PB; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD 20892;, Heinrichs D; VA Portland Health Care System, Portland, OR 97239;, Lin X; Department of Molecular and Cellular Oncology, University of Texas, MD Anderson Cancer Center, Houston, TX 77030;, Iwakura Y; Tokyo University of Science, Tokyo 278-0022, Japan; and., Wells CA; University of Queensland, Brisbane, Queensland 4072, Australia., Caspi RR; Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD 20892;, Rosenzweig HL; VA Portland Health Care System, Portland, OR 97239; Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR 97239; rosenzwh@ohsu.edu.

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2016 Apr 01; Vol. 196 (7), pp. 3148-58. Date of Electronic Publication: 2016 Feb 26.

NOD2 reduces the chemoresistance of melanoma by inhibiting the TYMS/PLK1 signaling axis.

Autor: Yun, Fang, Wu, Na, Yi, Xiaojia, Zhang, Xuedan, Feng, Yu, Ni, Qinxuan, Gai, Yanlong, Li, Enjiang, Yang, Zhe, Zhang, Qiao, Sai, Buqing, Kuang, Yingmin, Zhu, Yuechun

Publikováno v: Cell Death & Disease; Oct2024, Vol. 15 Issue 10, p1-17, 17p