Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Vanasa Nageswaran"'
Autor:
Paul-Lennard Mendez, Leon Obendorf, Jerome Jatzlau, Wiktor Burdzinski, Maria Reichenbach, Vanasa Nageswaran, Arash Haghikia, Verena Stangl, Christian Hiepen, Petra Knaus
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background Fluid shear stress enhances endothelial SMAD1/5 signaling via the BMP9-bound ALK1 receptor complex supported by the co-receptor Endoglin. While moderate SMAD1/5 activation is required to maintain endothelial quiescence, excessive
Externí odkaz:
https://doaj.org/article/f21e33dc96904caabcbae15c6de679ca
Autor:
Harsha V. Renikunta, Katina Lazarow, Yiqi Gong, Praphulla Chandra Shukla, Vanasa Nageswaran, Hector Giral, Adelheid Kratzer, Lennart Opitz, Felix B. Engel, Arash Haghikia, Sarah Costantino, Francesco Paneni, Jens Peter von Kries, Katrin Streckfuss-Bömeke, Ulf Landmesser, Philipp Jakob
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106593- (2023)
Summary: Ischemic cardiomyopathy, driven by loss of cardiomyocytes and inadequate proliferative response, persists to be a major global health problem. Using a functional high-throughput screening, we assessed differential proliferative potential of
Externí odkaz:
https://doaj.org/article/0397c180ca2842079b4aa0e59e2381c0
Autor:
Martina Gast, Vanasa Nageswaran, Andreas W. Kuss, Ana Tzvetkova, Xiaomin Wang, Liliana H. Mochmann, Pegah Ramezani Rad, Stefan Weiss, Stefan Simm, Tanja Zeller, Henry Voelzke, Wolfgang Hoffmann, Uwe Völker, Stefan B. Felix, Marcus Dörr, Antje Beling, Carsten Skurk, David-Manuel Leistner, Bernhard H. Rauch, Tetsuro Hirose, Bettina Heidecker, Karin Klingel, Shinichi Nakagawa, Wolfram C. Poller, Filip K. Swirski, Arash Haghikia, Wolfgang Poller
Publikováno v:
Cells, Vol 11, Iss 24, p 3970 (2022)
The evolutionary conserved NEAT1-MALAT1 gene cluster generates large noncoding transcripts remaining nuclear, while tRNA-like transcripts (mascRNA, menRNA) enzymatically generated from these precursors translocate to the cytosol. Whereas functions ha
Externí odkaz:
https://doaj.org/article/ec8ff563749948efa86a683c898e23a4
Autor:
Martina Gast, Vanasa Nageswaran, Andreas Kuss, Ana Tzvetkova, Xiaomin Wang, Liliana Mochmann, Pegah Ramezani-Rad, Stefan Weiss, Stefan Simm, Tanja Zeller, Henry Voelzke, Wolfgang Hoffmann, Uwe Völker, Stefan Felix, Marcus Dörr, Antje Beling, Carsten Skurk, David-Manuel Leistner, Bernhard Rauch, Tetsuro Hirose, Bettina Heidecker, Karin Klingel, Shinichi Nakagawa, Wolfram Poller, Filip Swirski, Arash Haghikia, Wolfgang Poller
The evolutionary conserved NEAT1-MALAT1 gene cluster generates large noncoding transcripts remaining nuclear, while tRNA-like transcripts (mascRNA, menRNA) enzymatically generated from these precursors translocate to the cytosol. NEAT1-/- and MALAT1-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a7a42e75f290709b2a3e0362feecb5
https://doi.org/10.21203/rs.3.rs-1540419/v2
https://doi.org/10.21203/rs.3.rs-1540419/v2
Autor:
Chinmay Kumar Dwibedi, Ahmed N. Hegazy, Johannes Kaisler, David M. Leistner, Annette Aigner, Aiden Haghikia, Stanley L. Hazen, Yvonne Döring, Valentina Tremaroli, Arash Haghikia, Nicolle Kränkel, David Schmidt, Markus M. Heimesaat, Paul Schumann, Christopher M. Strauch, Andrzej Jasina, Stefan Bereswill, Philipp Heinze, Ute Seeland, Dominik N. Müller, Geraldine Rauch, Ina Nemet, Fredrik Bäckhed, Johann Roessler, Uta Ceglarek, Oliver Soehnlein, Ralf Gold, Emiel P. C. van der Vorst, Ulf Landmesser, Friederike Zimmermann, Roodline Cineus, Vanasa Nageswaran
Publikováno v:
European Heart Journal, 43(6). Oxford University Press
Aims Atherosclerotic cardiovascular disease (ACVD) is a major cause of mortality and morbidity worldwide, and increased low-density lipoproteins (LDLs) play a critical role in development and progression of atherosclerosis. Here, we examined for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce082ae98013c4c937e3c28c224c445a
https://doi.org/10.1093/eurheartj/ehab644
https://doi.org/10.1093/eurheartj/ehab644
Autor:
Antje Beling, Martina Gast, A Tzvetkova, L Mochmann, Bernhard H. Rauch, Arash Haghikia, Andreas W. Kuss, Karin Klingel, Xiaomin Wang, Ulf Landmesser, Vanasa Nageswaran, Stefan Weiss, C Poller, Tanja Zeller, Shinichi Nakagawa
Publikováno v:
European Heart Journal. 42
Background The evolutionary conserved NEAT1-MALAT1 gene cluster encounters high interest in cardiovascular medicine and oncology. The cluster generates large primary transcripts which remain nuclear, whereas novel tRNA-like transcripts (mascRNA, menR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31f2f0df7d99f339ba1e355ab6d5898e
https://doi.org/10.1093/eurheartj/ehab724.3357
https://doi.org/10.1093/eurheartj/ehab724.3357
Autor:
Fabrizio Montecucco, Thomas F. Lüscher, Luca Liberale, Daniel S. Gaul, Giacomo Giacalone, Daria Vdovenko, Sarah Costantino, Julien Weber, Jürgen Pahla, Urs Eriksson, Maria Sessa, Giovanni G. Camici, Vanasa Nageswaran, Vera Fehr, Gerd A. Kullak-Ublick, Alexander Akhmedov, Aurora Semerano, Frank Ruschitzka, Christian M. Matter, Jürg H. Beer, Nicole R. Bonetti, Francesco Paneni
Publikováno v:
European Heart Journal. 41:1575-1587
Aims Aging is an established risk factor for stroke; genes regulating longevity are implicated in the pathogenesis of ischaemic stroke where to date, therapeutic options remain limited. The blood–brain barrier (BBB) is crucially involved in ischaem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bdf56c4e49b9522a247eb1254f9b1e3
https://doi.org/10.1093/eurheartj/ehz712
https://doi.org/10.1093/eurheartj/ehz712
Autor:
Frank Ruschitzka, Kimon Stamatelopoulos, Luca Liberale, Giovanni G. Camici, Melroy X. Miranda, Nicole R. Bonetti, Vanasa Nageswaran, Konstantinos Stellos, Francesco Paneni, Jürg H. Beer, Alexander Akhmedov, Nikolaos I. Vlachogiannis, Fabrizio Montecucco, Thomas F. Lüscher, Sarah Costantino, Yustina M. Puspitasari, Lena Schwarz
AIMS Arterial thrombosis as a result of plaque rupture or erosion is a key event in acute cardiovascular events. Sirtuin 5 (SIRT5) belongs to the lifespan-regulating sirtuin superfamily and has been implicated in acute ischemic stroke and cardiac hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ebda8ee2d276530ca3818d24aab3c8b
Autor:
Patricia Wüst, Fabrizio Montecucco, Thomas F. Lüscher, Jürg H. Beer, Candela Diaz-Cañestro, Luca Liberale, Johannes Bohacek, Giovanni G. Camici, Nicole R. Bonetti, Vanasa Nageswaran
BACKGROUND Endothelial cells regulate the formation of blood clots thus, genes selectively expressed in these cells could primarily determine thrombus formation. Apold1(apolipoprotein L domain containing 1) is a gene expressed by endothelial cells; w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77594541e2c8e3787f24f05f6d298aa
https://doi.org/10.5167/uzh-180309
https://doi.org/10.5167/uzh-180309
Autor:
Nikolaos I. Vlachogiannis, Fabrizio Montecucco, Thomas F. Lüscher, Melroy X. Miranda, Konstantinos Stellos, Kimon Stamatelopoulos, Luca Liberale, J H Beer, Nicole R. Bonetti, Vanasa Nageswaran, Alexander Akhmedov, Giovanni G. Camici
Publikováno v:
Atherosclerosis. 315:e78-e79
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5edf40ce89a291bab02fd4f3e4f1a075
https://doi.org/10.1016/j.atherosclerosis.2020.10.242
https://doi.org/10.1016/j.atherosclerosis.2020.10.242