Loss of STING impairs lactogenic differentiation.

Autor: Vickers, Ramiah R., Wyatt, Garhett L., Sanchez, Lilia, VanPortfliet, Jordyn J., West, A. Phillip, Porter, Weston W.

Publikováno v: Development (09501991); Oct2024, Vol. 151 Issue 19, p1-16, 16p

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Assessing Mitochondrial DNA Release into the Cytosol and Subsequent Activation of Innate Immune-related Pathways in Mammalian Cells.

Autor: Bryant, Joshua D., Yuanjiu Lei, VanPortfliet, Jordyn J., Winters, Ashley D., West, A. Phillip

Publikováno v: Current Protocols; Feb2022, Vol. 2 Issue 2, p1-31, 31p

Caspase-11 drives macrophage hyperinflammation in models of Polg-related mitochondrial disease.

Autor: VanPortfliet JJ; The Jackson Laboratory, Bar Harbor, Maine 04609, USA.; Department of Microbial Pathogenesis and Immunology, School of Medicine, Texas A&M University, Bryan, Texas 77807, USA., Lei Y; Department of Microbial Pathogenesis and Immunology, School of Medicine, Texas A&M University, Bryan, Texas 77807, USA.; Department of Pathology, Yale School of Medicine, New Haven, CT 06520, USA., Martinez CG; Department of Microbial Pathogenesis and Immunology, School of Medicine, Texas A&M University, Bryan, Texas 77807, USA., Wong J; The Jackson Laboratory, Bar Harbor, Maine 04609, USA., Pflug K; Department of Cell Biology and Genetics, School of Medicine, Texas A&M University, Bryan, Texas 77807, USA., Sitcheran R; Department of Cell Biology and Genetics, School of Medicine, Texas A&M University, Bryan, Texas 77807, USA., Kneeland SC; The Jackson Laboratory, Bar Harbor, Maine 04609, USA., Murray SA; The Jackson Laboratory, Bar Harbor, Maine 04609, USA., McGuire PJ; Metabolism, Infection and Immunity Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, 20892, USA., Cannon CL; Department of Microbial Pathogenesis and Immunology, School of Medicine, Texas A&M University, Bryan, Texas 77807, USA., West AP; The Jackson Laboratory, Bar Harbor, Maine 04609, USA.; Department of Microbial Pathogenesis and Immunology, School of Medicine, Texas A&M University, Bryan, Texas 77807, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 May 25. Date of Electronic Publication: 2024 May 25.