Mechanisms Regulating Early Mesendodermal Differentiation of Human Embryonic Stem Cells: A Dissertation

Autor: VanOudenhove, Jennifer J.

Publikováno v: Morningside Graduate School of Biomedical Sciences Dissertations and Theses.

Key regulatory events take place at very early stages of human embryonic stem cell (hESC) differentiation to accommodate their ability to differentiate into different lineages; this work examines two separate regulatory events. To investigate precise

Externí odkaz: https://escholarship.umassmed.edu/gsbs_diss/849
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1853&context=gsbs_diss

Precocious Phenotypic Transcription-Factor Expression during Early Development

Autor: VanOudenhove, Jennifer J., Medina, Ricardo, Ghule, Prachi N., Lian, Jane B., Stein, Janet L., Zaidi, Sayyed K., Stein, Gary

A novel role for phenotypic transcription factors in very early differentiation was recently observed and merits further study to elucidate what role this precocious expression may have in development. The RUNX1 transcription factor exhibits selectiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d55b46c183ce359ff79e3ea3c1cc7b30
https://europepmc.org/articles/PMC5336526/

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Precocious Phenotypic Transcription-Factor Expression During Early Development.

Autor: VanOudenhove JJ; Department of Biochemistry and University of Vermont Cancer Center, University of Vermont College of Medicine, 89 Beaumont Avenue, Burlington, Vermont 05405.; Department of Cell and Developmental Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655., Medina R; Department of Cell and Developmental Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655., Ghule PN; Department of Biochemistry and University of Vermont Cancer Center, University of Vermont College of Medicine, 89 Beaumont Avenue, Burlington, Vermont 05405., Lian JB; Department of Biochemistry and University of Vermont Cancer Center, University of Vermont College of Medicine, 89 Beaumont Avenue, Burlington, Vermont 05405., Stein JL; Department of Biochemistry and University of Vermont Cancer Center, University of Vermont College of Medicine, 89 Beaumont Avenue, Burlington, Vermont 05405., Zaidi SK; Department of Biochemistry and University of Vermont Cancer Center, University of Vermont College of Medicine, 89 Beaumont Avenue, Burlington, Vermont 05405., Stein GS; Department of Biochemistry and University of Vermont Cancer Center, University of Vermont College of Medicine, 89 Beaumont Avenue, Burlington, Vermont 05405.

Publikováno v: Journal of cellular biochemistry [J Cell Biochem] 2017 May; Vol. 118 (5), pp. 953-958. Date of Electronic Publication: 2017 Jan 11.