The mSQUASH is a feasible and valid measurement tool to uniformly assess daily physical activity in patients with rheumatic diseases

Autor: Suzanne Arends, Anneke Spoorenberg, Hendrika Bootsma, Kornelis S M van der Geest, Davy Paap, Lianne Gensler, Karina de Leeuw, Yvonne M van der Kraan, Ellen Thovmasyan, Noa Ausma, Helene Kokol, Marlies Carbo, Stan C Kieskamp

Publikováno v: RMD Open, Vol 10, Iss 4 (2024)

Background The modified Short QUestionnaire to ASsess Health-enhancing physical activity (mSQUASH) was originally developed and validated in Dutch patients with axial spondyloarthritis (axSpA). To support world-wide distribution, applicability and co

Externí odkaz: https://doaj.org/article/08fe5685c46a4e93b91c8ed34a3e9b91

CD64 as novel molecular imaging marker for the characterization of synovitis in rheumatoid arthritis

Autor: Wessel F. Theeuwes, Irene Di Ceglie, Daphne N. Dorst, Arjen B. Blom, Desiree L. Bos, Thomas Vogl, Sander W. Tas, Pilar Jimenez-Royo, Mats Bergstrom, Matthew Cleveland, Peter M. van der Kraan, Peter Laverman, Marije I. Koenders, Peter L. van Lent, Martijn H. J. van den Bosch

Publikováno v: Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-15 (2023)

Abstract Background Rheumatoid arthritis (RA) is one of the most prevalent and debilitating joint diseases worldwide. RA is characterized by synovial inflammation (synovitis), which is linked to the development of joint destruction. Magnetic resonanc

Externí odkaz: https://doaj.org/article/2aad6123f8ac4ee5adcf05a7f4fb72f2

Tailored anticoagulant treatment after a first venous thromboembolism: protocol of the Leiden Thrombosis Recurrence Risk Prevention (L-TRRiP) study - cohort-based randomised controlled trial

Autor: Saskia le Cessie, Nick van Es, Michiel Coppens, Karina Meijer, Suzanne C Cannegieter, Saskia Middeldorp, Menno V Huisman, Frederikus A Klok, Geert-Jan Geersing, Annette W G van der Velden, Elske M van den Akker-van Marle, Albert T A Mairuhu, M Elske van den Akker-van Marle, Laura M Faber, Tjerk de Nijs, Remy H H Bemelmans, Coen van Guldener, Marcel A van de Ree, Marieke J.H. Wermer, Tessa Elling, Carolien van Netten, Milou A M Stals, Rick Roos, J Louise I Burggraaf-van Delft, Nienke van Rein, Jan-Willem K van den Berg, Coty Y Bruggeman, Marissa Cloos-van Balen, Matthijs Eefting, Yvonne Ende-Verhaar, Wouter K de Jong, Fleur Kleijwegt, Ted Koster, Cees Kroon, Saskia Kuipers, Jenneke Leentjens, Dieuwke Luijten, Ilse Schrover, Janneke Swart-Heikens, Yavuz Bilgin, Marleen Goddrie, Pieter Jobse, Suzanne Jong, Brianne Murphy, Carla Boekholt, Danick Werner, Laura Kratz, Marjolein Kremers, Monique Schilders, Gideon Hajer, Bas Langeveld, Saskia Teunisse-de Recht, Annemiek Bogerd, Ymke Broers, Stan Kolman, Sanjay Sankatsing, Lenneke van Tol, Edith Beishuizen, Shantie Bharatsingh, Edith Boersma, Annemarie van der Kraan-Donker, Sabine van Arnhem, Fransien Croon-de Boer, Ad Dees, J P (Hanneke) van Embden, Roxane Heller, Merel Hoogendorp, Roel Jonkhoff, Roel J J M van de Laar, Corry Leunis-de Ruiter, Patricia Scherpenisse-Klopstra, Tom L H Stellema, Kim Warink, Lizanne E van den Akker, Eleonora C Camilleri, Tess R C Huibregtse, Ingeborg de Jonge, Ruben Y Kok, Inger N Kunnekes, Lejla Mahic, Hinke C Nagtegaal, Petra J Noordijk, Hülya Oztürk, Alexia M van der Ploeg, Vibeke Schmidt, Anne-Marie Schuitemaker, Vera C Slootweg, Mark J R Smeets, Milou Thibaudier, Marco Dam, Swopkje de Jong, Hanneke van der Velde, Evertine Abbink, Carlinda Bresser, Simone Sissing, Soerajja Bhoelan, Èmese Heijkoop, Francien Huisman, Mark Lenssen, Anja B U Makelburg, Karen H Thedinga, Marja A J Voskuilen, Femke Yspeerd, Sandra Brookman, Titia Lamberts, Inge Paas, Janneke Swart Heikens, Janneke van den Brink, Aline van de Vendel, Ellis S. van Etten

Publikováno v: BMJ Open, Vol 14, Iss 3 (2024)

Introduction Patients with a first venous thromboembolism (VTE) are at risk of recurrence. Recurrent VTE (rVTE) can be prevented by extended anticoagulant therapy, but this comes at the cost of an increased risk of bleeding. It is still uncertain whe

Externí odkaz: https://doaj.org/article/a64444f5ad18406f879dce721db0685e

P146: BeginNGS, an artificial intelligence-enabled genome sequencing system for newborn screening of 409 childhood genetic disorders

Autor: Jennifer Schleit, Meredith Wright, Lauren Olsen, Eric Blincow, Sara Caylor, Christina Chambers, Guillermo del Angel, Katarzyna (Kasia) Ellsworth, Annette Feigenbaum, Erwin Frise, Lucia Guidugli, Kevin Hall, Christian Hansen, Charlotte Hobbs, Mark Kiel, Chad Krilow, Chris Kunard, YongHyun Kwon, Rao Madhavrao, Shyamal Mehtalia, William Mowrey, Jennie Le, Jeremy Leipzig, Yupu Liang, Rebecca Mardach, Danny Oh, Mallory Owen, Liana Protopsaltis, Erica Sanford Kobayashi, Gunter Scharer, Brandon Schultz, Seth Shelnutt, Laurie Smith, Duke Tran, Lucita Van Der Kraan, Kristen Wigby, Mary Willis, Aaron Wolen, Mark Yandell, Thomas Defay, Stephen Kingsmore

Publikováno v: Genetics in Medicine Open, Vol 2, Iss , Pp 101043- (2024)

Externí odkaz: https://doaj.org/article/5daec32c1b634cde9bb11add9157b198

Scalable, high quality, whole genome sequencing from archived, newborn, dried blood spots

Autor: Yan Ding, Mallory Owen, Jennie Le, Sergey Batalov, Kevin Chau, Yong Hyun Kwon, Lucita Van Der Kraan, Zaira Bezares-Orin, Zhanyang Zhu, Narayanan Veeraraghavan, Shareef Nahas, Matthew Bainbridge, Joe Gleeson, Rebecca J. Baer, Gretchen Bandoli, Christina Chambers, Stephen F. Kingsmore

Publikováno v: npj Genomic Medicine, Vol 8, Iss 1, Pp 1-9 (2023)

Abstract Universal newborn screening (NBS) is a highly successful public health intervention. Archived dried bloodspots (DBS) collected for NBS represent a rich resource for population genomic studies. To fully harness this resource in such studies,

Externí odkaz: https://doaj.org/article/d52683be3c8840f3a3efba386f5f9b2e