Zobrazeno 1 - 10 of 859 pro vyhledávání: '"Van den Berg WB"'
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Akademický článek
Secukinumab for rheumatology: development and its potential place in therapy
Autor: Koenders MI, van den Berg WB
Publikováno v: Drug Design, Development and Therapy, Vol 2016, Iss Issue 1, Pp 2069-2080 (2016)
Marije I Koenders, Wim B van den Berg Experimental Rheumatology, Radboud University Medical Center, Nijmegen, the Netherlands Abstract: Rheumatic disease is not a single disorder, but a group of more than 100 diseases that affect joints, connective t
Externí odkaz: https://doaj.org/article/2eb6c6123f5e4bbba6fb06d1a00085c6
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2
Induction of osteoarthritis by intra-articular injection of collagenase in mice. Strain and sex related differences
Autor: van der Kraan Pm, Blankevoort L, Vitters El, van den Berg Wb, van Osch Gj
Publikováno v: Osteoarthritis and cartilage. 1(3)
To study the effects of strain and sex on the development of injury-induced osteoarthritis (OA) in murine knee joints, two doses of highly purified bacterial collagenase (10 units and 30 units) were injected into male and female mice of two closely r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df25ba8de622716bbeb213133b80770b
https://pubmed.ncbi.nlm.nih.gov/15449423
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3
Does TGF-ß Protect Articular Cartilage in Vivo?
Autor: van der Kraan Pm, van Beuningen Hm, Arntz Oj, van den Berg Wb
Publikováno v: Joint Destruction in Arthritis and Osteoarthritis ISBN: 9783034874441
Repeated intraarticular injections of transforming growth factor beta cause stimulation of articular cartilage proteoglycan synthesis, influx of inflammatory cells, fibrosis and osteophyte formation. When injected together with interleukin-1, TGF-bet
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7bf275cb067999e1edf39ce61ad88b46
https://doi.org/10.1007/978-3-0348-7442-7_14
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5
Variable TGF-ß Receptor Expression Regulates TGF-ß Responses of Articular Chondrocytes
Autor: Vitters El, van den Berg Wb, Glansbeek Hl, van der Kraan Pm
Publikováno v: Joint Destruction in Arthritis and Osteoarthritis ISBN: 9783034874441
TGF-beta inhibits the proteoglycan synthesis of freshly isolated articular chondrocytes while TGF-beta stimulates the proteoglycan synthesis of articular chondrocytes cultured for 14 days. To investigate if this differential effect was the result of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0db9ca2c13aaea5cdc3ca2c372265c4e
https://doi.org/10.1007/978-3-0348-7442-7_16
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7
In Vivo Evidence for a Key Role of Il-1 in Cartilage Destruction in Experimental Arthritis
Autor: van den Berg Wb, Otterness I, Leo A. B. Joosten, Arntz Oj, van de Loo Fa
Publikováno v: Drugs in Inflammation ISBN: 9783034874076
Cartilage destruction in murine antigen induced arthritis is characterized by enhanced degradation of proteoglycans and inhibition of chondrocyte proteoglycan synthesis. Within this model common NSAIDs only suppress joint swelling, and to some extent
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::05d027eabc1ee8b130b5eed2cff66e3c
https://doi.org/10.1007/978-3-0348-7405-2_21
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