Beyond DNA binding - a review of the potential mechanisms mediating quinacrine's therapeutic activities in parasitic infections, inflammation, and cancers

Autor: Van Waes Carter, Ehsanian Reza, Feller Stephan M

Publikováno v: Cell Communication and Signaling, Vol 9, Iss 1, p 13 (2011)

Abstract This is an in-depth review of the history of quinacrine as well as its pharmacokinetic properties and established record of safety as an FDA-approved drug. The potential uses of quinacrine as an anti-cancer agent are discussed with particula

Externí odkaz: https://doaj.org/article/158873d0bd4c4131a276901ac7760feb

Pharmacological Inhibition of HSP90 Radiosensitizes Head and Neck Squamous Cell Carcinoma Xenograft by Inhibition of DNA Damage Repair, Nucleotide Metabolism, and Radiation-Induced Tumor Vasculogenesis

Autor: Naz, Sarwat ^*, Leiker, Andrew J. ^*, Choudhuri, Rajani ^*, Preston, Olivia ^*, Sowers, Anastasia L. ^*, Gohain, Sangeeta ^*, Gamson, Janet ^*, Mathias, Askale ^*, Van Waes, Carter, Cook, John A. ^*, Mitchell, James B. ^*

Publikováno v: In International Journal of Radiation Oncology, Biology, Physics 1 August 2021 110(5):1295-1305

Cisplatin and oxaliplatin induce similar immunogenic changes in preclinical models of head and neck cancer

Autor: Park, So-Jin, Ye, Wenda, Xiao, Roy, Silvin, Christopher, Padget, Michelle, Hodge, James W., Van Waes, Carter, Schmitt, Nicole C.

Publikováno v: In Oral Oncology August 2019 95:127-135

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

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Publikováno v: In Cell Reports 3 April 2018 23(1):194-212

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