Sprouty-4 inhibits transformed cell growth, migration and invasion, and EMT and is regulated by Wnt7A through PPARγ in non-small cell lung cancer

Autor: Tennis, MA, Van Scoyk, MM, Freeman, SV, Vandervest, KM, Nemenoff, RA, Winn, RA

Sprouty proteins are potent receptor tyrosine kinase inhibitors that antagonize growth factor signaling and are involved in lung development. However, little is known about the regulation or targets of Sprouty-4 (Spry4) in lung cancer. Our study aime

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::46745c8438abd0455a97c646d0110f10
https://europepmc.org/articles/PMC2888899/

Sprouty-4 inhibits transformed cell growth, migration and invasion, and epithelial-mesenchymal transition, and is regulated by Wnt7A through PPARgamma in non-small cell lung cancer.

Autor: Tennis MA; University of Colorado at Denver and Health Sciences Center, 12700 East 19th Avenue, Box C272, RC2 9th Floor, Aurora, CO 80045, USA. Meredith.tennis@ucdenver.edu, Van Scoyk MM, Freeman SV, Vandervest KM, Nemenoff RA, Winn RA

Publikováno v: Molecular cancer research : MCR [Mol Cancer Res] 2010 Jun; Vol. 8 (6), pp. 833-43. Date of Electronic Publication: 2010 May 25.