Large variability in plasma efavirenz concentration in Papua New Guinea HIV/AIDS patients associated with high frequency of CYP2B6 516T allele.

Autor: Bordin Andriguetti N; Discipline of Pharmacology, Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia., Van Schalkwyk HK; Discipline of Pharmacology, Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia., Barratt DT; Discipline of Physiology, Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia., Tucci J; Department of Pharmacy & Biomedical Sciences, La Trobe University Bendigo Campus, Bendigo, Victoria, Australia., Pumuye P; School of Medicine and Health Sciences, University of Papua New Guinea, National Capital District, Papua New Guinea., Somogyi AA; Discipline of Pharmacology, Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia.

Publikováno v: Clinical and translational science [Clin Transl Sci] 2021 Nov; Vol. 14 (6), pp. 2521-2531. Date of Electronic Publication: 2021 Aug 20.