The effect of Tyloxapol on the metabolome of Mycobacterium tuberculosis.

Autor: Opperman M; Human Metabolomics, North-West University, Potchefstroom, South Africa. Electronic address: monique.opperman@nwu.ac.za., Pietersen RD; DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, SAMRC Centre for TB Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa. Electronic address: ray@sun.ac.za., Loots DT; Human Metabolomics, North-West University, Potchefstroom, South Africa. Electronic address: dutoit.loots@nwu.ac.za., van Reenen M; Human Metabolomics, North-West University, Potchefstroom, South Africa. Electronic address: 12791733@nwu.ac.za., Beukes D; Human Metabolomics, North-West University, Potchefstroom, South Africa. Electronic address: 13128531@nwu.ac.za., Baker B; DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, SAMRC Centre for TB Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa. Electronic address: brubaker@sun.ac.za., du Preez I; Human Metabolomics, North-West University, Potchefstroom, South Africa. Electronic address: ilse.dupreez@nwu.ac.za.

Publikováno v: Journal of microbiological methods [J Microbiol Methods] 2024 Nov; Vol. 226, pp. 107028. Date of Electronic Publication: 2024 Sep 06.

Protein kinase C-delta (PKCδ), a marker of inflammation and tuberculosis disease progression in humans, is important for optimal macrophage killing effector functions and survival in mice

Autor: Parihar, S P, Ozturk, M, Marakalala, M J, Loots, D T, Hurdayal, R, Maasdorp, D Beukes, Van Reenen, M, Zak, D E, Darboe, F, Penn-Nicholson, A, Hanekom, W A, Leitges, M, Scriba, T J, Guler, R, Brombacher, F

Publikováno v: In Mucosal Immunology March 2018 11(2):496-511

Characterizing poorly controlled type 2 diabetes using ¹ H-NMR metabolomics.

Autor: Theron IJ; Human Metabolomics, Department of Biochemistry, Faculty of Natural and Agricultural Sciences, North-West University, Potchefstroom, South Africa., Mason S; Human Metabolomics, Department of Biochemistry, Faculty of Natural and Agricultural Sciences, North-West University, Potchefstroom, South Africa., van Reenen M; Human Metabolomics, Department of Biochemistry, Faculty of Natural and Agricultural Sciences, North-West University, Potchefstroom, South Africa., Stander Z; Human Metabolomics, Department of Biochemistry, Faculty of Natural and Agricultural Sciences, North-West University, Potchefstroom, South Africa., Kleynhans L; DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Stellenbosch University, Cape Town, South Africa.; Mater Research Institute, The University of Queensland, Translational Research Institute, Brisbane, Australia., Ronacher K; DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Stellenbosch University, Cape Town, South Africa.; Mater Research Institute, The University of Queensland, Translational Research Institute, Brisbane, Australia.; Australian Infectious Diseases Research Centre, The University of Queensland, Brisbane, Australia., Loots DT; Human Metabolomics, Department of Biochemistry, Faculty of Natural and Agricultural Sciences, North-West University, Potchefstroom, South Africa. dutoit.loots@nwu.ac.za.

Publikováno v: Metabolomics : Official journal of the Metabolomic Society [Metabolomics] 2024 May 11; Vol. 20 (3), pp. 54. Date of Electronic Publication: 2024 May 11.

Metabolic Alterations in Mothers Living with HIV and Their HIV-Exposed, Uninfected Infants.

Autor: du Toit LDV; Department of Immunology, Faculty of Health Sciences, University of Pretoria, Pretoria 0001, South Africa.; UP Research Centre for Maternal, Fetal, Newborn and Child Health Care Strategies, University of Pretoria, Pretoria 0001, South Africa.; Maternal and Infant Health Care Strategies Research Unit, South African Medical Research Council, Pretoria 0001, South Africa., Mason S; Human Metabolomics, Faculty of Natural and Agricultural Sciences, North-West University, Potchefstroom 2520, South Africa., van Reenen M; Human Metabolomics, Faculty of Natural and Agricultural Sciences, North-West University, Potchefstroom 2520, South Africa., Rossouw TM; Department of Immunology, Faculty of Health Sciences, University of Pretoria, Pretoria 0001, South Africa.; UP Research Centre for Maternal, Fetal, Newborn and Child Health Care Strategies, University of Pretoria, Pretoria 0001, South Africa.; Maternal and Infant Health Care Strategies Research Unit, South African Medical Research Council, Pretoria 0001, South Africa., Louw R; Human Metabolomics, Faculty of Natural and Agricultural Sciences, North-West University, Potchefstroom 2520, South Africa.

Publikováno v: Viruses [Viruses] 2024 Feb 19; Vol. 16 (2). Date of Electronic Publication: 2024 Feb 19.

Phenylalanine metabolism and tetrahydrobiopterin bio-availability in COVID-19 and HIV.

Autor: Mason S; Human Metabolomics, Faculty of Natural and Agricultural Sciences, North-West University, Potchefstroom, South Africa., van Reenen M; Human Metabolomics, Faculty of Natural and Agricultural Sciences, North-West University, Potchefstroom, South Africa., Rossouw T; Department of Immunology, University of Pretoria, Pretoria, South Africa., Lindeque Z; Human Metabolomics, Faculty of Natural and Agricultural Sciences, North-West University, Potchefstroom, South Africa., Louw R; Human Metabolomics, Faculty of Natural and Agricultural Sciences, North-West University, Potchefstroom, South Africa.

Publikováno v: Heliyon [Heliyon] 2023 Apr; Vol. 9 (4), pp. e15010. Date of Electronic Publication: 2023 Mar 28.