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Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci

Autor: Asselbergs, Folkert W., Guo, Yiran, Van Iperen, Erik P. A., Sivapalaratnam, Suthesh, Tragante, Vinicius, Lanktree, Matthew B., Lange, Leslie A., Almoguera, Berta, Appelman, Yolande E., Barnard, John, Baumert, Jens, Beitelshees, Amber L., Bhangale, Tushar R., Chen, Yii-Der Ida, Gaunt, Tom R., Gong, Yan, Hopewell, Jemma C., Johnson, Toby, Kleber, Marcus E., Langaee, Taimour Y., Li, Mingyao, Li, Yun R., Liu, Kiang, McDonough, Caitrin W., Meijs, Matthijs F. L., Middelberg, Rita P. S., Musunuru, Kiran, Nelson, Christopher P., O’Connell, Jeffrey R., Padmanabhan, Sandosh, Pankow, James S., Pankratz, Nathan, Rafelt, Suzanne, Rajagopalan, Ramakrishnan, Romaine, Simon P. R., Schork, Nicholas J., Shaffer, Jonathan, Shen, Haiqing, Smith, Erin N., Tischfield, Sam E., Van Der Most, Peter J., Van Vliet-Ostaptchouk, Jana V., Verweij, Niek, Volcik, Kelly A., Zhang, Li, Bailey, Kent R., Bailey, Kristian M., Bauer, Florianne, Boer, Jolanda M. A., Braund, Peter S., Burt, Amber, Burton, Paul R., Buxbaum, Sarah G., Chen, Wei, Cooper-DeHoff, Rhonda M., Cupples, L. Adrienne, DeJong, Jonas S., Delles, Christian, Duggan, David, Fornage, Myriam, Furlong, Clement E., Glazer, Nicole, Gums, John G., Hastie, Claire, Holmes, Michael V., Illig, Thomas, Kirkland, Susan A., Kivimaki, Mika, Klein, Ronald, Klein, Barbara E., Kooperberg, Charles, Kottke-Marchant, Kandice, Kumari, Meena, LaCroix, Andrea Z., Mallela, Laya, Murugesan, Gurunathan, Ordovas, Jose, Ouwehand, Willem H., Post, Wendy S., Saxena, Richa, Scharnagl, Hubert, Schreiner, Pamela J., Shah, Tina, Shields, Denis C., Shimbo, Daichi, Srinivasan, Sathanur R., Stolk, Ronald P., Swerdlow, Daniel I., Taylor Jr., Herman A., Topol, Eric J., Toskala, Elina, Van Pelt, Joost L., Van Setten, Jessica, Yusuf, Salim, Whittaker, John C., Zwinderman, A. H., Anand, Sonia S., Balmforth, Anthony J., Berenson, Gerald S., Bezzina, Connie R., Boehm, Bernhard O., Boerwinkle, Eric, Casas, Juan P., Caulfield, Mark J., Clarke, Robert, Connell, John M., Cruickshanks, Karen J., Davidson, Karina W., Day, Ian N. M., De Bakker, Paul I. W., Doevendans, Pieter A., Dominiczak, Anna F., Hall, Alistair S., Hartman, Catharina A., Hengstenberg, Christian, Hillege, Hans L., Hofker, Marten H., Humphries, Steve E., Jarvik, Gail P., Johnson, Julie A., Kaess, Bernhard M., Kathiresan, Sekar, Koenig, Wolfgang, Lawlor, Debbie A., Marz, Winfried, Melander, Olle, Mitchell, Braxton D., Montgomery, Grant W., Munroe, Patricia B., Murray, Sarah S., Newhouse, Stephen J., Onland-Moret, N. Charlotte, Poulter, Neil, Psaty, Bruce, Redline, Susan, Rich, Stephen S., Rotter, Jerome I., Schunkert, Heribert, Sever, Peter, Shuldiner, Alan R., Silverstein, Roy L., Stanton, Alice, Thorand, Barbara, Trip, Mieke D., Tsai, Michael Y., Van Der Harst, Pim, Van Der Schoot, Ellen, Van Der Schouw, Yvonne T., Verschuren, W. M. Monique, Watkins, Hugh, Wilde, Arthur A. M., Wolffenbuttel, Bruce H. R., Whitfield, John B., Hovingh, G. Kees, Ballantyne, Christie M., Wijmenga, Cisca, Reilly, Muredach P., Martin, Nicholas G., LifeLines Cohort Study

Genome-wide association studies (GWASs) have identified many SNPs underlying variations in plasma-lipid levels. We explore whether additional loci associated with plasma-lipid phenotypes, such as high-density lipoprotein cholesterol (HDL-C), low-dens

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::df0bcd7469da48d4849819b64897ee44