SiglecF(HI) Marks Late-Stage Neutrophils of the Infarcted Heart: A Single-Cell Transcriptomic Analysis of Neutrophil Diversification

Autor: Aaron D. Aguirre, Van Kim Ninh, Zhenxing Fu, Claire Zhang, Joan Heller Brown, Kevin R. King, David M Calcagno, Shigeki Miyamoto, Avinash Toomu, Kenneth Huang

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 4 (2021)

Background Neutrophils are thought to be short‐lived first responders to tissue injuries such as myocardial infarction (MI), but little is known about their diversification or dynamics. Methods and Results We permanently ligated the left anterior d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d99f273805f977a57f0998aa087441
https://pubmed.ncbi.nlm.nih.gov/33525909

NLRP3 Inflammasome Products IL‐1beta and IL‐18 Have A Direct Effect on Cardiomyocytes

Autor: Joan Heller Brown, Jacqueline Bella Anderson Enni, Van Kim Ninh, Shigeki Miyamoto

Publikováno v: The FASEB Journal. 34:1-1

Author(s): Anderson Enni, Jacqueline Bella | Advisor(s): Heller Brown, Joan | Abstract: We previously demonstrated a significant role for NLRP3 inflammasome activation in cardiomyocytes in cardiac inflammation, remodeling and contractile dysfunction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c931c637d0b384d21c27c143d458ee22
https://doi.org/10.1096/fasebj.2020.34.s1.06628

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