Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Van Iperen, Erik PA"'
Autor:
Schmidt, Amand F., Swerdlow, Daniel I, Holmes, Michael V, Patel, Riyaz S., Fairhurst-Hunter, Zammy, Lyall, Donald M, Hartwig, Fernando Pires, Horta, Bernardo Lessa, Hyppönen, Elina, Power, Christine, Moldovan, Max, van Iperen, Erik Pa, Hovingh, G. Kees, Demuth, Ilja, Norman, Kristina, Steinhagen-Thiessen, Elisabeth, Demuth, Juri, Bertram, Lars, Liu, Tian, Coassin, Stefan, Willeit, Johann, Kiechl, Stefan, Willeit, Karin, Mason, Dan, Wright, John, Morris, Richard W, Wanamethee, Goya, Whincup, Peter H, Ben-Shlomo, Yoav, McLachlan, Stela, Price, Jackie F, Kivimaki, Mika, Welch, Catherine, Sanchez-Galvez, Adelaida, Marques-Vidal, Pedro, Nicolaides, Andrew N., Panayiotou, Andrie G., Onland-Moret, N Charlotte, van der Schouw, Yvonne T, Matullo, Giuseppe, Fiorito, Giovanni, Guarrera, Simonetta, Sacerdote, Carlotta, Wareham, Nicholas J., Langenberg, Claudia, Scott, Robert A, Luan, Jian'an, Smith, Daniel J, Maitland-van der Zee, Anke H, Baranova, Ekaterina V, LifeLines Cohort Study Group
Publikováno v:
The Lancet Diabetes and Endocrinology, 5(2), 97. Elsevier BV
BACKGROUND: Statin treatment and variants in the gene encoding HMG-CoA reductase are associated with reductions in both the concentration of LDL cholesterol and the risk of coronary heart disease, but also with modest hyperglycaemia, increased bodywe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4ccc5691707b9c9b7d695408b0245213
https://dspace.library.uu.nl/handle/1874/362237
https://dspace.library.uu.nl/handle/1874/362237
Autor:
Nüesch, Eveline, Dale, Caroline, Palmer, Tom M, White, Jon, Keating, Brendan J, van Iperen, Erik Pa, Goel, Anuj, Padmanabhan, Sandosh, Asselbergs, Folkert W, Verschuren, W M, Wijmenga, C, Van der Schouw, Y T, Onland-Moret, N C, Lange, Leslie A, Hovingh, G K, Sivapalaratnam, Suthesh, Morris, Richard W, Whincup, Peter H, Wannamethe, Goya S, Gaunt, Tom R, Ebrahim, Shah, Steel, Laura, Nair, Nikhil, Reiner, Alexander P, Kooperberg, Charles, Strachan, Mark Wj, Robertson, Christine M, Kleber, Marcus E, Delgado, Graciela, März, Winfried, Melander, Olle, Dominiczak, Anna F, Farrall, Martin, Watkins, Hugh, Leusink, Maarten, Maitland-van der Zee, Anke H, de Groot, Mark Ch, Dudbridge, Frank, Hingorani, Aroon, Ben-Shlomo, Yoav, Lawlor, Debbie A, Amuzu, A, Caufield, M, Cavadino, A, Cooper, J, Davies, T L, Wilson, James F, Bolton, Jennifer, McLachlan, Stela, Price, Jacqueline F
Publikováno v:
Nüesch, E, Dale, C, Palmer, T M, White, J, Keating, B J, van Iperen, E P, Goel, A, Padmanabhan, S, Asselbergs, F W, Verschuren, W M, Wijmenga, C, Van der Schouw, Y T, Onland-Moret, N C, Lange, L A, Hovingh, G K, Sivapalaratnam, S, Morris, R W, Whincup, P H, Wannamethe, G S, Gaunt, T R, Ebrahim, S, Steel, L, Nair, N, Reiner, A P, Kooperberg, C, Strachan, M W, Robertson, C M, Kleber, M E, Delgado, G, März, W, Melander, O, Dominiczak, A F, Farrall, M, Watkins, H, Leusink, M, Maitland-van der Zee, A H, de Groot, M C, Dudbridge, F, Hingorani, A, Ben-Shlomo, Y, Lawlor, D A, Amuzu, A, Caufield, M, Cavadino, A, Cooper, J, Davies, T L, Wilson, J F, Bolton, J & McLachlan, S & Price, J F 2015, ' Adult height, coronary heart disease and stroke : a multi-locus Mendelian randomization meta-analysis ', International Journal of Epidemiology . https://doi.org/10.1093/ije/dyv074
BACKGROUND: We investigated causal effect of completed growth, measured by adult height, on coronary heart disease (CHD), stroke and cardiovascular traits, using instrumental variable (IV) Mendelian randomization meta-analysis.METHODS: We developed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3094::b93cb897e19af40fb11ae83e94c2531e
https://hdl.handle.net/20.500.11820/9c53d039-bd9e-4cc0-b60b-855f657e5b23
https://hdl.handle.net/20.500.11820/9c53d039-bd9e-4cc0-b60b-855f657e5b23
Autor:
Ganesh, Santhi K, Tragante, Vinicius, Guo, Wei, Guo, Yiran, Lanktree, Matthew B, Smith, Erin N, Johnson, Toby, Castillo, Berta Almoguera, Barnard, John, Baumert, Jens, Chang, Yen-Pei Christy, Elbers, Clara C, Farrall, Martin, Fischer, Mary E, Franceschini, Nora, Gaunt, Tom R, Gho, Johannes MIH, Gieger, Christian, Gong, Yan, Isaacs, Aaron, Kleber, Marcus E, Mateo Leach, Irene, McDonough, Caitrin W, Meijs, Matthijs FL, Mellander, Olle, Molony, Cliona M, Nolte, Ilja M, Padmanabhan, Sandosh, Price, Tom S, Rajagopalan, Ramakrishnan, Shaffer, Jonathan, Shah, Sonia, Shen, Haiqing, Soranzo, Nicole, van der Most, Peter J, Van Iperen, Erik PA, Van Setten, Jessica, Vonk, Judith M, Zhang, Li, Beitelshees, Amber L, Berenson, Gerald S, Bhatt, Deepak L, Boer, Jolanda MA, Boerwinkle, Eric, Burkley, Ben, Burt, Amber, Chakravarti, Aravinda, Chen, Wei, Cooper-Dehoff, Rhonda M, Curtis, Sean P, Dreisbach, Albert, Duggan, David, Ehret, Georg B, Fabsitz, Richard R, Fornage, Myriam, Fox, Ervin, Furlong, Clement E, Gansevoort, Ron T, Hofker, Marten H, Hovingh, G Kees, Kirkland, Susan A, Kottke-Marchant, Kandice, Kutlar, Abdullah, Lacroix, Andrea Z, Langaee, Taimour Y, Li, Yun R, Lin, Honghuang, Liu, Kiang, Maiwald, Steffi, Malik, Rainer, CARDIOGRAM, METASTROKE, Murugesan, Gurunathan, Newton-Cheh, Christopher, O'Connell, Jeffery R, Onland-Moret, N Charlotte, Ouwehand, Willem H, Palmas, Walter, Penninx, Brenda W, Pepine, Carl J, Pettinger, Mary, Polak, Joseph F, Ramachandran, Vasan S, Ranchalis, Jane, Redline, Susan, Ridker, Paul M, Rose, Lynda M, Scharnag, Hubert, Schork, Nicholas J, Shimbo, Daichi, Shuldiner, Alan R, Srinivasan, Sathanur R, Stolk, Ronald P, Taylor, Herman A, Thorand, Barbara, Trip, Mieke D, van Duijn, Cornelia M, Verschuren, W Monique, Wijmenga, Cisca, Winkelmann, Bernhard R, Wyatt, Sharon
Publikováno v:
Human molecular genetics, vol 22, iss 8
Blood pressure (BP) is a heritable determinant of risk for cardiovascular disease (CVD). To investigate genetic associations with systolic BP (SBP), diastolic BP (DBP), mean arterial pressure (MAP) and pulse pressure (PP), we genotyped ∼50 000 sing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1273710eb6287dcc440e8c23006a5ea2
https://escholarship.org/uc/item/16d246b2
https://escholarship.org/uc/item/16d246b2
Autor:
Lanktree, Matthew B, Guo, Yiran, Murtaza, Muhammed, Glessner, Joseph T, Bailey, Swneke D, Onland-Moret, N Charlotte, Lettre, Guillaume, Ongen, Halit, Rajagopalan, Ramakrishnan, Johnson, Toby, Shen, Haiqing, Nelson, Christopher P, Klopp, Norman, Baumert, Jens, Padmanabhan, Sandosh, Pankratz, Nathan, Pankow, James S, Shah, Sonia, Taylor, Kira, Barnard, John, Peters, Bas J, Maloney, Cliona M, Lobmeyer, Maximilian T, Stanton, Alice, Zafarmand, M Hadi, Romaine, Simon PR, Mehta, Amar, van Iperen, Erik PA, Gong, Yan, Price, Tom S, Smith, Erin N, Kim, Cecilia E, Li, Yun R, Asselbergs, Folkert W, Atwood, Larry D, Bailey, Kristian M, Bhatt, Deepak, Bauer, Florianne, Behr, Elijah R, Bhangale, Tushar, Boer, Jolanda MA, Boehm, Bernhard O, Bradfield, Jonathan P, Brown, Morris, Braund, Peter S, Burton, Paul R, Carty, Cara, Chandrupatla, Hareesh R, Chen, Wei, Connell, John, Dalgeorgou, Chrysoula, Boer, Anthonius de, Drenos, Fotios, Elbers, Clara C, Fang, James C, Fox, Caroline S, Frackelton, Edward C, Fuchs, Barry, Furlong, Clement E, Gibson, Quince, Gieger, Christian, Goel, Anuj, Grobbee, Diederik E, Hastie, Claire, Howard, Philip J, Huang, Guan-Hua, Johnson, W Craig, Li, Qing, Kleber, Marcus E, Klein, Barbara EK, Klein, Ronald, Kooperberg, Charles, Ky, Bonnie, Lacroix, Andrea, Lanken, Paul, Lathrop, Mark, Li, Mingyao, Marshall, Vanessa, Melander, Olle, Mentch, Frank D, Meyer, Nuala J, Monda, Keri L, Montpetit, Alexandre, Murugesan, Gurunathan, Nakayama, Karen, Nondahl, Dave, Onipinla, Abiodun, Rafelt, Suzanne, Newhouse, Stephen J, Otieno, F George, Patel, Sanjey R, Putt, Mary E, Rodriguez, Santiago, Safa, Radwan N, Sawyer, Douglas B, Schreiner, Pamela J, Simpson, Claire, Sivapalaratnam, Suthesh, Srinivasan, Sathanur R, Suver, Christine
Publikováno v:
American journal of human genetics, vol 88, iss 1
Height is a classic complex trait with common variants in a growing list of genes known to contribute to the phenotype. Using a genecentric genotyping array targeted toward cardiovascular-related loci, comprising 49,320 SNPs across approximately 2000
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::03ab7ce20d81b047f2050106093d63cf
https://escholarship.org/uc/item/9mk379qd
https://escholarship.org/uc/item/9mk379qd
A genetic risk score is associated with statin-induced low-density lipoprotein cholesterol lowering.
Autor:
Leusink, Maarten, Maitland-van der Zee, Anke H, Ding, Bo, Drenos, Fotios, van Iperen, Erik PA, Warren, Helen R, Caulfield, Mark J, Cupples, L Adrienne, Cushman, Mary, Hingorani, Aroon D, Hoogeveen, Ron C, Hovingh, G Kees, Kumari, Meena, Lange, Leslie A, Munroe, Patricia B, Nyberg, Fredrik, Schreiner, Pamela J, Sivapalaratnam, Suthesh, de Bakker, Paul IW, de Boer, Anthonius
Publikováno v:
Pharmacogenomics; Apr2016, Vol. 17 Issue 6, p583-591, 9p
Autor:
Nüesch E; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.; CTU Bern, Department of Clinical Research and Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland., Dale C; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK., Palmer TM; Warwick Medical School, University of Warwick, Coventry, UK.; Department of Mathematics and Statistics, Lancaster University, Lancaster, UK., White J; UCL Genetics Institute, Department of Genetics, Evolution and Environment, University College London, London, UK., Keating BJ; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Surgery.; Division of Genetics, University of Pennsylvania, Philadelphia., van Iperen EP; Department of Biostatistics, Academic Medical Center Amsterdam, Amsterdam, The Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, The Netherlands., Goel A; Wellcome Trust Centre for Human Genetics and Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Padmanabhan S; Institute of Cardiovascular and Medical Sciences, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Asselbergs FW; Department of Cardiology, Division Heart and Lungs, University Medical Centre Utrecht, Utrecht, The Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, The Netherlands.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK., Verschuren WM, Wijmenga C, Van der Schouw YT, Onland-Moret NC; EPIC-NL, Bilthoven and Utrecht, The Netherlands., Lange LA; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Hovingh GK; Department of Vascular Medicine, Academic Medical Center Amsterdam, Amsterdam, The Netherlands., Sivapalaratnam S; Department of Vascular Medicine, Academic Medical Center Amsterdam, Amsterdam, The Netherlands., Morris RW; Department of Primary Care & Population Health, University College London, London, UK., Whincup PH; Population Health Research Institute, St George's, University of London, London, UK., Wannamethe GS; Department of Primary Care & Population Health, University College London, London, UK., Gaunt TR; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK.; School of Social and Community Medicine, University of Bristol, Bristol, UK., Ebrahim S; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK., Steel L; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Nair N; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Reiner AP; Department of Epidemiology, University of Washington, Seattle, WA, USA / Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Wilson JF; Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Bolton JL; Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., McLachlan S; Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Price JF; Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Strachan MW; Metabolic Unit, Western General Hospital, Edinburgh, UK., Robertson CM; Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Kleber ME; Fifth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany., Delgado G; Fifth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany., März W; Medical Clinic V (Nephrology, Hypertensiology, Endocrinology, Diabetolgy, and Rheumatology), Mannheim Medical Faculty, University of Heidelberg, Germany, Synlab Academy, Synlab Services GmbH, Mannheim and Augsburg, Germany, Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Austria., Melander O; Lund University, Sweden., Dominiczak AF; Institute of Cardiovascular and Medical Sciences, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Farrall M; Wellcome Trust Centre for Human Genetics and Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Watkins H; Wellcome Trust Centre for Human Genetics and Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Leusink M; Division of Pharmacoepidemiology & Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands., Maitland-van der Zee AH; Division of Pharmacoepidemiology & Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands., de Groot MC; Division of Pharmacoepidemiology & Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands., Dudbridge F; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK., Hingorani A; Department of Epidemiology and Public Health, University College London Medical School, London, UK., Ben-Shlomo Y; School of Social and Community Medicine, University of Bristol, Bristol, UK., Lawlor DA; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK.; School of Social and Community Medicine, University of Bristol, Bristol, UK., Amuzu A, Caufield M, Cavadino A, Cooper J, Davies TL, Drenos F, Engmann J, Finan C, Giambartolomei C, Hardy R, Humphries SE, Hypponen E, Kivimaki M, Kuh D, Kumari M, Ong K, Plagnol V, Power C, Richards M, Shah S, Shah T, Sofat R, Talmud PJ, Wareham N, Warren H, Whittaker JC, Wong A, Zabaneh D; UCLEB, London, Edinburgh and Bristol, UK., Davey Smith G; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK.; School of Social and Community Medicine, University of Bristol, Bristol, UK., Wells JC; Childhood Nutrition Research Centre, UCL Institute of Child Health, London, UK., Leon DA; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.; Department of Community Medicine, Arctic University of Norway, UiT., Holmes MV; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK.; Department of Surgery and Clinical Epidemiology Unit, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK., Casas JP; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK.
Publikováno v:
International journal of epidemiology [Int J Epidemiol] 2016 Dec 01; Vol. 45 (6), pp. 1927-1937.