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pro vyhledávání: '"Van Hilburn"'
Autor:
Li Yu, Lyudmila Bazhenova, Kathryn Gold, Lisa Tran, Van Hilburn, Peter Vu, Sandip Pravin Patel
Publikováno v:
Translational lung cancer research, vol 11, iss 3
BackgroundSmall cell lung cancer (SCLC) transformation is one of the mechanisms of drug resistance to tyrosine kinase inhibitors (TKIs) in advanced epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC) and represents an i
Publikováno v:
Expert opinion on pharmacotherapy. 22(14)
Introduction: Alectinib is a second-generation inhibitor of anaplastic lymphoma kinase (ALK) and RET. Phase III clinical trials have established its superiority to crizotinib in the first-line ALK inhibitor-naive setting. Studies also support its use